Distinct populations of corticotropin-releasing factor (CRF) neurons mediate divergent yet complementary defensive behaviors in response to a threat

Optogenetic manipulations of CeA-CRF neurons modulate pain- and anxiety-like behaviors in neuropathic pain and control rats

(2022) Mariacristina Mazzitelli et al.   NEUROPHARMACOLOGY

Corticotropin releasing factor (CRF) systems: Promoting cocaine pursuit without distress via incentive motivation

(2022) Hannah M. Baumgartner et al.   PLoS One

Generation of a CRF1-Cre transgenic rat and the role of central amygdala CRF1 cells in nociception and anxiety-like behavior

(2022) Marcus M Weera et al.   eLife

Activating corticotropin releasing factor (CRF) systems in nucleus accumbens, amygdala, and bed nucleus of stria terminalis: Incentive motivation or aversive motivation?

(2021) Hannah M. Baumgartner et al.   BIOLOGICAL PSYCHIATRY

Distinct circuits in rat central amygdala for defensive behaviors evoked by socially signaled imminent versus remote danger

(2021) Karolina Andraka et al.   CURRENT BIOLOGY

Extended amygdala circuits are differentially activated by context fear conditioning in male and female rats

(2021) Louise Urien et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Delineation of an insula-BNST circuit engaged by struggling behavior that regulates avoidance in mice

(2021) Joseph R. Luchsinger et al.   Nature Communications

Neurochemically distinct populations of the bed nucleus of stria terminalis modulate innate fear response to weak threat evoked by predator odor stimuli

(2021) Biborka Bruzsik et al.   Neurobiology of Stress

Paraventricular nucleus CRH neurons encode stress controllability and regulate defensive behavior selection

(2020) Núria Daviu et al.   NATURE NEUROSCIENCE

Persistent activation of central amygdala CRF neurons helps drive the immediate fear extinction deficit

(2020) Yong S. Jo et al.   Nature Communications

The role of central amygdala corticotropin-releasing factor in predator odor stress-induced avoidance behavior and escalated alcohol drinking in rats

(2020) Marcus M. Weera et al.   NEUROPHARMACOLOGY

Dynamic remodeling of a basolateral-to-central amygdala glutamatergic circuit across fear states

(2019) Nolan D. Hartley et al.   NATURE NEUROSCIENCE

Dissecting the Roles of GABA and Neuropeptides from Rat Central Amygdala CRF Neurons in Anxiety and Fear Learning

(2019) Matthew B. Pomrenze et al.   Cell Reports

Amygdalar corticotropin-releasing factor mediates stress-induced anxiety

(2019) Ana Paula Ventura-Silva et al.   BRAIN RESEARCH

Parallel circuits from the bed nuclei of stria terminalis to the lateral hypothalamus drive opposing emotional states

(2018) William J. Giardino et al.   NATURE NEUROSCIENCE

The CRF Family of Neuropeptides and their Receptors - Mediators of the Central Stress Response

(2018) Nina Dedic et al.   Current Molecular Pharmacology

The Central Amygdala Corticotropin-releasing hormone (CRH) Neurons Modulation of Anxiety-like Behavior and Hippocampus-dependent Memory in Mice

(2018) Tanvi Paretkar et al.   NEUROSCIENCE

α2A-Adrenergic Receptor Activation Decreases Parabrachial Nucleus Excitatory Drive onto BNST CRF Neurons and Reduces Their Activity In Vivo

(2018) Tracy L. Fetterly et al.   JOURNAL OF NEUROSCIENCE

A CORTICOTROPIN RELEASING FACTOR NETWORK IN THE EXTENDED AMYGDALA FOR ANXIETY

(2018) Matthew B. Pomrenze et al.   JOURNAL OF NEUROSCIENCE

Endocannabinoid control of the insular-bed nucleus of the stria terminalis circuit regulates negative affective behavior associated with alcohol abstinence

(2018) Samuel W. Centanni et al.   NEUROPSYCHOPHARMACOLOGY

Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear

(2017) A Asok et al.   MOLECULAR PSYCHIATRY

A competitive inhibitory circuit for selection of active and passive fear responses

(2017) Jonathan P. Fadok et al.   NATURE

A Central Amygdala CRF Circuit Facilitates Learning about Weak Threats

(2017) Christina A. Sanford et al.   NEURON

Basolateral to Central Amygdala Neural Circuits for Appetitive Behaviors

(2017) Joshua Kim et al.   NEURON

The roots of empathy: Through the lens of rodent models

(2017) K.Z. Meyza et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

A Quantitative Analysis of the Distribution of CRH Neurons in Whole Mouse Brain

(2017) Jie Peng et al.   Frontiers in Neuroanatomy

Activation of corticotropin releasing factor-containing neurons in the rat central amygdala and bed nucleus of the stria terminalis following exposure to two different anxiogenic stressors

(2016) Ryan K. Butler et al.   BEHAVIOURAL BRAIN RESEARCH

Distribution of corticotropin-releasing factor neurons in the mouse brain: a study using corticotropin-releasing factor-modified yellow fluorescent protein knock-in mouse

(2016) Junko Kono et al.   Brain Structure & Function

Genetic cell targeting uncovers specific neuronal types and distinct subregions in the bed nucleus of the stria terminalis

(2016) Amanda Q. Nguyen et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Targeting Corticotropin-Releasing Factor Projections from the Oval Nucleus of the Bed Nucleus of the Stria Terminalis Using Cell-Type Specific Neuronal Tracing Studies in Mouse and Rat Brain

(2016) J. Dabrowska et al.   JOURNAL OF NEUROENDOCRINOLOGY

Serotonin engages an anxiety and fear-promoting circuit in the extended amygdala

(2016) Catherine A. Marcinkiewcz et al.   NATURE

Hypothalamic CRH neurons orchestrate complex behaviours after stress

(2016) Tamás Füzesi et al.   Nature Communications

Diversity of Reporter Expression Patterns in Transgenic Mouse Lines Targeting Corticotropin-Releasing Hormone-Expressing Neurons

(2015) Yuncai Chen et al.   ENDOCRINOLOGY

Revisiting the Role of Infralimbic Cortex in Fear Extinction with Optogenetics

(2015) F. H. Do-Monte et al.   JOURNAL OF NEUROSCIENCE

A temporal shift in the circuits mediating retrieval of fear memory

(2015) Fabricio H. Do-Monte et al.   NATURE

NPY signaling inhibits extended amygdala CRF neurons to suppress binge alcohol drinking

(2015) Kristen E Pleil et al.   NATURE NEUROSCIENCE

A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits

(2015) Matthew B. Pomrenze et al.   Frontiers in Neuroscience

Importance of CRF Receptor-Mediated Mechanisms of the Bed Nucleus of the Stria Terminalis in the Processing of Anxiety and Pain

(2014) Lee Tran et al.   NEUROPSYCHOPHARMACOLOGY

Grin1 Receptor Deletion within CRF Neurons Enhances Fear Memory

(2014) Georgette Gafford et al.   PLoS One

Coming to terms with fear

(2014) J. E. LeDoux   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Immediate early gene and neuropeptide expression following exposure to the predator odor 2,5-dihydro-2,4,5-trimethylthiazoline (TMT)

(2013) Arun Asok et al.   BEHAVIOURAL BRAIN RESEARCH

Striatal-Enriched Protein Tyrosine Phosphatase—STEPs Toward Understanding Chronic Stress-Induced Activation of Corticotrophin Releasing Factor Neurons in the Rat Bed Nucleus of the Stria Terminalis

(2013) Joanna Dabrowska et al.   BIOLOGICAL PSYCHIATRY

A Corticotropin Releasing Factor Pathway for Ethanol Regulation of the Ventral Tegmental Area in the Bed Nucleus of the Stria Terminalis

(2013) Y. Silberman et al.   JOURNAL OF NEUROSCIENCE

Inhibition of corticotropin releasing factor expression in the central nucleus of the amygdala attenuates stress-induced behavioral and endocrine responses

(2013) Leah B. Callahan et al.   Frontiers in Neuroscience

Central CRF neurons are not created equal: phenotypic differences in CRF-containing neurons of the rat paraventricular hypothalamus and the bed nucleus of the stria terminalis

(2013) Joanna Dabrowska et al.   Frontiers in Neuroscience

Effects of continuously enhanced corticotropin releasing factor expression within the bed nucleus of the stria terminalis on conditioned and unconditioned anxiety

(2012) K S Sink et al.   MOLECULAR PSYCHIATRY

Neuropeptide receptor ligands as drugs for psychiatric diseases: the end of the beginning?

(2012) Guy Griebel et al.   NATURE REVIEWS DRUG DISCOVERY

Cell-type specific deletion of GABA(A) 1 in corticotropin-releasing factor-containing neurons enhances anxiety and disrupts fear extinction

(2012) G. M. Gafford et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The effect of CRF2 receptor antagonists on rat conditioned fear responses and c-Fos and CRF expression in the brain limbic structures

(2011) A. Skórzewska et al.   BEHAVIOURAL BRAIN RESEARCH

Site-Specific Genetic Manipulation of Amygdala Corticotropin-Releasing Factor Reveals Its Imperative Role in Mediating Behavioral Response to Challenge

(2011) Limor Regev et al.   BIOLOGICAL PSYCHIATRY

Comparison of CRF-immunoreactive neurons distribution in mouse and rat brains and selective induction of Fos in rat hypothalamic CRF neurons by abdominal surgery

(2011) Lixin Wang et al.   BRAIN RESEARCH

Sex-dependent and differential responses to acute restraint stress of corticotropin-releasing factor-producing neurons in the rat paraventricular nucleus, central amygdala, and bed nucleus of the stria terminalis

(2011) Linda Sterrenburg et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Neuroanatomical evidence for reciprocal regulation of the corticotrophin-releasing factor and oxytocin systems in the hypothalamus and the bed nucleus of the stria terminalis of the rat: Implications for balancing stress and affect

(2011) Joanna Dabrowska et al.   PSYCHONEUROENDOCRINOLOGY

A Novel Transgenic Mouse for Gene-Targeting Within Cells That Express Corticotropin-Releasing Factor

(2010) Elizabeth I. Martin et al.   BIOLOGICAL PSYCHIATRY

Encoding of conditioned fear in central amygdala inhibitory circuits

(2010) Stephane Ciocchi et al.   NATURE

Transgenic Mice Expressing Green Fluorescent Protein under the Control of the Corticotropin-Releasing Hormone Promoter

(2009) Tamar Alon et al.   ENDOCRINOLOGY

The Central Nucleus of the Amygdala and Corticotropin-Releasing Factor: Insights into Contextual Fear Memory

(2009) M. W. Pitts et al.   JOURNAL OF NEUROSCIENCE

Neural regulation of endocrine and autonomic stress responses

(2009) Yvonne M. Ulrich-Lai et al.   NATURE REVIEWS NEUROSCIENCE

Phasic vs Sustained Fear in Rats and Humans: Role of the Extended Amygdala in Fear vs Anxiety

(2009) Michael Davis et al.   NEUROPSYCHOPHARMACOLOGY

Stressor controllability and Fos expression in stress regulatory regions in mice

(2009) X. Liu et al.   PHYSIOLOGY & BEHAVIOR

Fear potentiation is associated with hypothalamic–pituitary–adrenal axis function in PTSD

(2009) Tanja Jovanovic et al.   PSYCHONEUROENDOCRINOLOGY

Role of the extended amygdala in short-duration versus sustained fear: a tribute to Dr. Lennart Heimer

(2008) David L. Walker et al.   Brain Structure & Function

Novel Aspects of Glutamatergic Signalling in the Neuroendocrine System

(2008) E. Hrabovszky et al.   JOURNAL OF NEUROENDOCRINOLOGY

Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning

(2008) B. J. Kolber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gender differences in corticotropin and corticosterone secretion and corticotropin-releasing factor mRNA expression in the paraventricular nucleus of the hypothalamus and the central nucleus of the amygdala in response to footshock stress or psychological stress in rats

(2008) Azusa Iwasaki-Sekino et al.   PSYCHONEUROENDOCRINOLOGY