Activating corticotropin releasing factor (CRF) systems in nucleus accumbens, amygdala, and bed nucleus of stria terminalis: Incentive motivation or aversive motivation?

Revisiting the Stress Concept: Implications for Affective Disorders

(2020) Bruce S. McEwen et al.   JOURNAL OF NEUROSCIENCE

Desire or Dread from Nucleus Accumbens Inhibitions: Reversed by Same-Site Optogenetic Excitations

(2020) H.M. Baumgartner et al.   JOURNAL OF NEUROSCIENCE

The central amygdala recruits mesocorticolimbic circuitry for pursuit of reward or pain

(2020) Shelley M. Warlow et al.   Nature Communications

Inactivation of a CRF-dependent amygdalofugal pathway reverses addiction-like behaviors in alcohol-dependent rats

(2019) Giordano de Guglielmo et al.   Nature Communications

New viral-genetic mapping uncovers an enrichment of corticotropin-releasing hormone-expressing neuronal inputs to the nucleus accumbens from stress-related brain regions

(2019) Christy A. Itoga et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Striatal cholinergic interneurons are a novel target of corticotropin releasing factor

(2019) Julia C. Lemos et al.   JOURNAL OF NEUROSCIENCE

The upside of stress: a mechanism for the positive motivational role of corticotropin releasing factor

(2019) Julia C. Lemos et al.   NEUROPSYCHOPHARMACOLOGY

Corticotropin-Releasing Factor (CRF) circuit modulation of cognition and motivation

(2019) Sofiya Hupalo et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Manipulations of central amygdala neurotensin neurons alter the consumption of ethanol and sweet fluids in mice

(2019) María Luisa Torruella-Suárez et al.   JOURNAL OF NEUROSCIENCE

Dissecting the Roles of GABA and Neuropeptides from Rat Central Amygdala CRF Neurons in Anxiety and Fear Learning

(2019) Matthew B. Pomrenze et al.   Cell Reports

Amygdalar corticotropin-releasing factor mediates stress-induced anxiety

(2019) Ana Paula Ventura-Silva et al.   BRAIN RESEARCH

Parallel circuits from the bed nuclei of stria terminalis to the lateral hypothalamus drive opposing emotional states

(2018) William J. Giardino et al.   NATURE NEUROSCIENCE

Addiction and stress: An allostatic view

(2018) George F. Koob et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Enhanced CRFR1-Dependent Regulation of a Ventral Tegmental Area to Prelimbic Cortex Projection Establishes Susceptibility to Stress-Induced Cocaine Seeking

(2018) Oliver Vranjkovic et al.   JOURNAL OF NEUROSCIENCE

A CORTICOTROPIN RELEASING FACTOR NETWORK IN THE EXTENDED AMYGDALA FOR ANXIETY

(2018) Matthew B. Pomrenze et al.   JOURNAL OF NEUROSCIENCE

Optogenetic central amygdala stimulation intensifies and narrows motivation for cocaine

(2017) Shelley M. Warlow et al.   JOURNAL OF NEUROSCIENCE

Optogenetic silencing of a corticotropin-releasing factor pathway from the central amygdala to the bed nucleus of the stria terminalis disrupts sustained fear

(2017) A Asok et al.   MOLECULAR PSYCHIATRY

A competitive inhibitory circuit for selection of active and passive fear responses

(2017) Jonathan P. Fadok et al.   NATURE

Basolateral to Central Amygdala Neural Circuits for Appetitive Behaviors

(2017) Joshua Kim et al.   NEURON

Targeting Corticotropin-Releasing Factor Projections from the Oval Nucleus of the Bed Nucleus of the Stria Terminalis Using Cell-Type Specific Neuronal Tracing Studies in Mouse and Rat Brain

(2016) J. Dabrowska et al.   JOURNAL OF NEUROENDOCRINOLOGY

Stress increases GABAergic neurotransmission in CRF neurons of the central amygdala and bed nucleus stria terminalis

(2016) John G. Partridge et al.   NEUROPHARMACOLOGY

Lost in Translation: CRF1 Receptor Antagonists and Addiction Treatment

(2016) Yavin Shaham et al.   NEUROPSYCHOPHARMACOLOGY

The CRF1 Antagonist Verucerfont in Anxious Alcohol-Dependent Women: Translation of Neuroendocrine, But not of Anti-Craving Effects

(2016) Melanie L Schwandt et al.   NEUROPSYCHOPHARMACOLOGY

Activation of D2 dopamine receptor-expressing neurons in the nucleus accumbens increases motivation

(2016) Carina Soares-Cunha et al.   Nature Communications

Stress-Induced Reinstatement of Drug Seeking: 20 Years of Progress

(2015) John R Mantsch et al.   NEUROPSYCHOPHARMACOLOGY

A Transgenic Rat for Investigating the Anatomy and Function of Corticotrophin Releasing Factor Circuits

(2015) Matthew B. Pomrenze et al.   Frontiers in Neuroscience

Corticotropin releasing factor: A key role in the neurobiology of addiction

(2014) Eric P. Zorrilla et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Optogenetic Excitation of Central Amygdala Amplifies and Narrows Incentive Motivation to Pursue One Reward Above Another

(2014) M. J. F. Robinson et al.   JOURNAL OF NEUROSCIENCE

The CRH1 Antagonist GSK561679 Increases Human Fear But Not Anxiety as Assessed by Startle

(2014) Christian Grillon et al.   NEUROPSYCHOPHARMACOLOGY

The Corticotropin Releasing Hormone-1 (CRH1) Receptor Antagonist Pexacerfont in Alcohol Dependence: A Randomized Controlled Experimental Medicine Study

(2014) Laura E Kwako et al.   NEUROPSYCHOPHARMACOLOGY

Central CRF neurons are not created equal: phenotypic differences in CRF-containing neurons of the rat paraventricular hypothalamus and the bed nucleus of the stria terminalis

(2013) Joanna Dabrowska et al.   Frontiers in Neuroscience

Addiction is a Reward Deficit and Stress Surfeit Disorder

(2013) George F. Koob   Frontiers in Psychiatry

Severe stress switches CRF action in the nucleus accumbens from appetitive to aversive

(2012) Julia C. Lemos et al.   NATURE

Stressful life events predict eating disorder relapse following remission: Six-year prospective outcomes

(2011) Carlos M. Grilo et al.   INTERNATIONAL JOURNAL OF EATING DISORDERS

RNAscope

(2011) Fay Wang et al.   JOURNAL OF MOLECULAR DIAGNOSTICS

Glutamatergic and Dopaminergic Neurons Mediate Anxiogenic and Anxiolytic Effects of CRHR1

(2011) D. Refojo et al.   SCIENCE