Neural engineering with photons as synaptic transmitters

FLInt: single shot safe harbor transgene integration via Fluorescent Landmark Interference

(2023) Nawaphat Malaiwong et al.   G3-Genes Genomes Genetics

Selective control of synaptically-connected circuit elements by all-optical synapses

(2022) Mansi Prakash et al.   Communications Biology

Synthetic cells with self-activating optogenetic proteins communicate with natural cells

(2022) Omer Adir et al.   Nature Communications

Reprogramming the topology of the nociceptive circuit in C. elegans reshapes sexual behavior

(2022) Vladyslava Pechuk et al.   CURRENT BIOLOGY

Volumetric imaging of fast cellular dynamics with deep learning enhanced bioluminescence microscopy

(2022) Luis Felipe Morales-Curiel et al.   Communications Biology

The sex-specific VC neurons are mechanically activated motor neurons that facilitate serotonin-induced egg laying in C. elegans

(2021) Richard J. Kopchock et al.   JOURNAL OF NEUROSCIENCE

Structural and developmental principles of neuropil assembly in C. elegans

(2021) Mark W. Moyle et al.   NATURE

Connectomes across development reveal principles of brain maturation

(2021) Daniel Witvliet et al.   NATURE

A genetically encoded tool for reconstituting synthetic modulatory neurotransmission and reconnect neural circuits in vivo

(2021) Josh D. Hawk et al.   Nature Communications

An asymmetric mechanical code ciphers curvature-dependent proprioceptor activity

(2021) Ravi Das et al.   Science Advances

Plants with genetically encoded autoluminescence

(2020) Tatiana Mitiouchkina et al.   NATURE BIOTECHNOLOGY

Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals

(2020) Yichi Su et al.   NATURE METHODS

Cellular Expression and Functional Roles of All 26 Neurotransmitter GPCRs in the C. elegans Egg-Laying Circuit

(2020) Robert W. Fernandez et al.   JOURNAL OF NEUROSCIENCE

A connectome and analysis of the adult Drosophila central brain

(2020) Louis K Scheffer et al.   eLife

Bioluminescence-Driven Optogenetics

(2020) Macià Sureda-Vives et al.   Life-Basel

Step‐function luminopsins for bimodal prolonged neuromodulation

(2019) Ken Berglund et al.   JOURNAL OF NEUROSCIENCE RESEARCH

An orange calcium-modulated bioluminescent indicator for non-invasive activity imaging

(2019) Younghee Oh et al.   Nature Chemical Biology

A Cellular-Resolution Atlas of the Larval Zebrafish Brain

(2019) Michael Kunst et al.   NEURON

Luciferase-LOV BRET enables versatile and specific transcriptional readout of cellular protein-protein interactions

(2019) Christina K Kim et al.   eLife

Whole-animal connectomes of both Caenorhabditis elegans sexes

(2019) Steven J. Cook et al.   NATURE

How to map the brain

(2019) Sarah DeWeerdt   NATURE

Moving beyond P values: data analysis with estimation graphics

(2019) Joses Ho et al.   NATURE METHODS

High-throughput multicolor optogenetics in microwell plates

(2019) Lukasz J. Bugaj et al.   Nature Protocols

Cortical layer–specific critical dynamics triggering perception

(2019) James H. Marshel et al.   SCIENCE

Quantitation of the neural silencing activity of anion channelrhodopsins in Caenorhabditis elegans and their applicability for long-term illumination

(2019) Taro Yamanashi et al.   Scientific Reports

Neural engineering: the process, applications, and its role in the future of medicine

(2019) Evon S Ereifej et al.   Journal of Neural Engineering

Bioluminescence Profiling of NanoKAZ/NanoLuc Luciferase Using a Chemical Library of Coelenterazine Analogues

(2019) Eloi P Coutant et al.   CHEMISTRY-A EUROPEAN JOURNAL

Reliability of an interneuron response depends on an integrated sensory state

(2019) May Dobosiewicz et al.   eLife

Rhodopsin optogenetic toolbox v2.0 for light-sensitive excitation and inhibition in Caenorhabditis elegans

(2018) Amelie Bergs et al.   PLoS One

An open-source platform for analyzing and sharing worm-behavior data

(2018) Avelino Javer et al.   NATURE METHODS

Architecture of the Mouse Brain Synaptome

(2018) Fei Zhu et al.   NEURON

Exact spike train inference via $\ell_{0}$ optimization

(2018) Sean Jewell et al.   Annals of Applied Statistics

Fast nonconvex deconvolution of calcium imaging data

(2018) Sean W Jewell et al.   BIOSTATISTICS

Pneumatic stimulation of C. elegans mechanoreceptor neurons in a microfluidic trap

(2017) Adam L. Nekimken et al.   LAB ON A CHIP

Silencing Neurons: Tools, Applications, and Experimental Constraints

(2017) J. Simon Wiegert et al.   NEURON

Luminopsins integrate opto- and chemogenetics by using physical and biological light sources for opsin activation

(2016) Ken Berglund et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Five colour variants of bright luminescent protein for real-time multicolour bioimaging

(2016) Kazushi Suzuki et al.   Nature Communications

Activity of the C. elegans egg-laying behavior circuit is controlled by competing activation and feedback inhibition

(2016) Kevin M Collins et al.   eLife

The CNS connectome of a tadpole larva of Ciona intestinalis (L.) highlights sidedness in the brain of a chordate sibling

(2016) Kerrianne Ryan et al.   eLife

Sensitive red protein calcium indicators for imaging neural activity

(2016) Hod Dana et al.   eLife

Luciferins Behave Like Drugs

(2015) David M. Mofford et al.   ACS Chemical Neuroscience

G1/S Inhibitors and the SWI/SNF Complex Control Cell-Cycle Exit during Muscle Differentiation

(2015) Suzan Ruijtenberg et al.   CELL

Illuminating circuitry relevant to psychiatric disorders with optogenetics

(2015) Elizabeth E Steinberg et al.   CURRENT OPINION IN NEUROBIOLOGY

Natural light-gated anion channels: A family of microbial rhodopsins for advanced optogenetics

(2015) E. G. Govorunova et al.   SCIENCE

Modeling the Spatiotemporal Dynamics of Light and Heat Propagation for In Vivo Optogenetics

(2015) Joseph M. Stujenske et al.   Cell Reports

A Circuit for Gradient Climbing in C. elegans Chemotaxis

(2015) Johannes Larsch et al.   Cell Reports

Scalable and Versatile Genome Editing Using Linear DNAs with Microhomology to Cas9 Sites in Caenorhabditis elegans

(2014) Alexandre Paix et al.   GENETICS

Mechanical characterization of bulk Sylgard 184 for microfluidics and microengineering

(2014) I D Johnston et al.   JOURNAL OF MICROMECHANICS AND MICROENGINEERING

Mechanical control of the sense of touch by β-spectrin

(2014) Michael Krieg et al.   NATURE CELL BIOLOGY

Channelrhodopsin-2-XXL, a powerful optogenetic tool for low-light applications

(2014) A. Dawydow et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rewiring neural circuits by the insertion of ectopic electrical synapses in transgenic C. elegans

(2014) Ithai Rabinowitch et al.   Nature Communications

NeuroElectro: a window to the world's neuron electrophysiology data

(2014) Shreejoy J. Tripathy et al.   Frontiers in Neuroinformatics

Modular Control of Glutamatergic Neuronal Identity in C. elegans by Distinct Homeodomain Proteins

(2013) Esther Serrano-Saiz et al.   CELL

Light-Emitting Channelrhodopsins for Combined Optogenetic and Chemical-Genetic Control of Neurons

(2013) Ken Berglund et al.   PLoS One

C. elegans Chemotaxis Assay

(2013) Olivia Margie et al.   Jove-Journal of Visualized Experiments

Basic Caenorhabditis elegans Methods: Synchronization and Observation

(2012) Montserrat Porta-de-la-Riva et al.   Jove-Journal of Visualized Experiments

The Neural Circuits and Synaptic Mechanisms Underlying Motor Initiation in C. elegans

(2011) Beverly J. Piggott et al.   CELL

DEG/ENaC but Not TRP Channels Are the Major Mechanoelectrical Transduction Channels in a C. elegans Nociceptor

(2011) Shana L. Geffeney et al.   NEURON

Optogenetic analysis of synaptic transmission in the central nervous system of the nematode Caenorhabditis elegans

(2011) Theodore H. Lindsay et al.   Nature Communications

Optogenetics

(2010) Karl Deisseroth   NATURE METHODS

The quest for action potentials in C. elegans neurons hits a plateau

(2009) Shawn R Lockery et al.   NATURE NEUROSCIENCE

A Self-Regulating Feed-Forward Circuit Controlling C. elegans Egg-Laying Behavior

(2008) Mi Zhang et al.   CURRENT BIOLOGY