Genetics of sexually dimorphic adipose distribution in humans

LDAK-GBAT: Fast and powerful gene-based association testing using summary statistics

(2022) Takiy-Eddine Berrandou et al.   AMERICAN JOURNAL OF HUMAN GENETICS

A regulatory variant at 3q21.1 confers an increased pleiotropic risk for hyperglycemia and altered bone mineral density

(2021) Nasa Sinnott-Armstrong et al.   Cell Metabolism

A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci

(2021) Amelia C. Joslin et al.   Nature Communications

Functional characterization of T2D-associated SNP effects on baseline and ER stress-responsive β cell transcriptional activation

(2021) Shubham Khetan et al.   Nature Communications

Use ggbreak to Effectively Utilize Plotting Space to Deal With Large Datasets and Outliers

(2021) Shuangbin Xu et al.   Frontiers in Genetics

Sex and gender: modifiers of health, disease, and medicine

(2020) Franck Mauvais-Jarvis et al.   LANCET

The impact of sex on gene expression across human tissues

(2020) Meritxell Oliva et al.   SCIENCE

Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution

(2019) Anne E. Justice et al.   NATURE GENETICS

Identification of a mesenchymal progenitor cell hierarchy in adipose tissue

(2019) David Merrick et al.   SCIENCE

Open Chromatin Profiling in Adipose Tissue Marks Genomic Regions with Functional Roles in Cardiometabolic Traits

(2019) Maren E. Cannon et al.   G3-Genes Genomes Genetics

CommonMind Consortium provides transcriptomic and epigenomic data for Schizophrenia and Bipolar Disorder

(2019) Gabriel E. Hoffman et al.   Scientific Data

Activity-by-contact model of enhancer–promoter regulation from thousands of CRISPR perturbations

(2019) Charles P. Fulco et al.   NATURE GENETICS

Causal relationships between obesity and the leading causes of death in women and men

(2019) Jenny C. Censin et al.   PLoS Genetics

Regulatory variants at KLF14 influence type 2 diabetes risk via a female-specific effect on adipocyte size and body composition

(2018) Kerrin S. Small et al.   NATURE GENETICS

Loss-of-function variants in ADCY3 increase risk of obesity and type 2 diabetes

(2018) Niels Grarup et al.   NATURE GENETICS

Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

(2018) Hilary K. Finucane et al.   NATURE GENETICS

Meta-analysis of genome-wide association studies for height and body mass index in ∼700000 individuals of European ancestry

(2018) Loic Yengo et al.   HUMAN MOLECULAR GENETICS

Meta-analysis of genome-wide association studies for body fat distribution in 694,649 individuals of European ancestry

(2018) Sara L Pulit et al.   HUMAN MOLECULAR GENETICS

The epidemiology of obesity

(2018) Yu Chung Chooi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Retinoids Regulate Adipogenesis Involving the TGFβ/SMAD and Wnt/β-Catenin Pathways in Human Bone Marrow Mesenchymal Stem Cells

(2017) Jun Cao et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

SGBS cells as a model of human adipocyte browning: A comprehensive comparative study with primary human white subcutaneous adipocytes

(2017) Chia Rou Yeo et al.   Scientific Reports

Systematic Functional Dissection of Common Genetic Variation Affecting Red Blood Cell Traits

(2016) Jacob C. Ulirsch et al.   CELL

Metabolic acceleration and the evolution of human brain size and life history

(2016) Herman Pontzer et al.   NATURE

Integrative approaches for large-scale transcriptome-wide association studies

(2016) Alexander Gusev et al.   NATURE GENETICS

Regulatory evolution of innate immunity through co-option of endogenous retroviruses

(2016) E. B. Chuong et al.   SCIENCE

Systematic mapping of functional enhancer–promoter connections with CRISPR interference

(2016) Charles P. Fulco et al.   SCIENCE

Fast and efficient QTL mapper for thousands of molecular phenotypes

(2015) Halit Ongen et al.   BIOINFORMATICS

The sexual dimorphism of obesity

(2015) Biff F. Palmer et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

New genetic loci link adipose and insulin biology to body fat distribution

(2015) Dmitry Shungin et al.   NATURE

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

Partitioning heritability by functional annotation using genome-wide association summary statistics

(2015) Hilary K Finucane et al.   NATURE GENETICS

An atlas of genetic correlations across human diseases and traits

(2015) Brendan Bulik-Sullivan et al.   NATURE GENETICS

Ancient Transposable Elements Transformed the Uterine Regulatory Landscape and Transcriptome during the Evolution of Mammalian Pregnancy

(2015) Vincent J. Lynch et al.   Cell Reports

Osteopetrorickets due to Snx10 Deficiency in Mice Results from Both Failed Osteoclast Activity and Loss of Gastric Acid-Dependent Calcium Absorption

(2015) Liang Ye et al.   PLoS Genetics

Visceral adipose tissue as a source of inflammation and promoter of atherosclerosis

(2014) Nikolaos Alexopoulos et al.   ATHEROSCLEROSIS

Activating transcription factor 4 regulates adipocyte differentiation via altering the coordinate expression of CCATT/enhancer binding protein β and peroxisome proliferator-activated receptor γ

(2014) Kaifan Yu et al.   FEBS Journal

Transcriptional Regulation of Adipocyte Differentiation: A Central Role for CCAAT/Enhancer-binding Protein (C/EBP) β

(2014) Liang Guo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Bayesian Test for Colocalisation between Pairs of Genetic Association Studies Using Summary Statistics

(2014) Claudia Giambartolomei et al.   PLoS Genetics

The Genotype-Tissue Expression (GTEx) project

(2013) John Lonsdale et al.   NATURE GENETICS

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Genome-wide association studies of obesity and metabolic syndrome

(2012) Tove Fall et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Genome-wide localization and expression profiling establish Sp2 as a sequence-specific transcription factor regulating vitally important genes

(2012) Gloria Terrados et al.   NUCLEIC ACIDS RESEARCH

Differential expression analysis of multifactor RNA-Seq experiments with respect to biological variation

(2012) Davis J. McCarthy et al.   NUCLEIC ACIDS RESEARCH

Transcriptional Control of Adipose Lipid Handling by IRF4

(2011) Jun Eguchi et al.   Cell Metabolism

edgeR: a Bioconductor package for differential expression analysis of digital gene expression data

(2009) M. D. Robinson et al.   BIOINFORMATICS

Thyroid hormone receptors regulate adipogenesis and carcinogenesis via crosstalk signaling with peroxisome proliferator-activated receptors

(2009) Changxue Lu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Distribution of body fat and risk of coronary heart disease in men and women

(2008) Dexter Canoy   CURRENT OPINION IN CARDIOLOGY

1000 Genomes project

(2008) Nayanah Siva   NATURE BIOTECHNOLOGY

The orphan nuclear receptor chicken ovalbumin upstream promoter-transcription factor II is a critical regulator of adipogenesis

(2008) Z. Xu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA