Programming inactive RNA-binding small molecules into bioactive degraders
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Programming inactive RNA-binding small molecules into bioactive degraders
Authors
Keywords
-
Journal
NATURE
Volume 618, Issue 7963, Pages 169-179
Publisher
Springer Science and Business Media LLC
Online
2023-05-25
DOI
10.1038/s41586-023-06091-8
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Chemical Evolution of Natural Product Structure
- (2022) Michael Grigalunas et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- PROTAC targeted protein degraders: the past is prologue
- (2022) Miklós Békés et al. NATURE REVIEWS DRUG DISCOVERY
- Reprogramming of Protein-Targeted Small-Molecule Medicines to RNA by Ribonuclease Recruitment
- (2021) Peiyuan Zhang et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Small-molecule targeted recruitment of a nuclease to cleave an oncogenic RNA in a mouse model of metastatic cancer
- (2020) Matthew G. Costales et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- How We Think about Targeting RNA with Small Molecules
- (2020) Matthew G. Costales et al. JOURNAL OF MEDICINAL CHEMISTRY
- Design of a small molecule that stimulates vascular endothelial growth factor A enabled by screening RNA fold–small molecule interactions
- (2020) Hafeez S. Haniff et al. Nature Chemistry
- Perspectives on targeting RNA with small molecules to capture opportunities at the intersection of chemistry, biology, and medicine
- (2019) Matthew D. Disney JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Fluorescent indicator displacement assays to identify and characterize small molecule interactions with RNA
- (2019) Sarah L. Wicks et al. METHODS
- A cross-linking approach to map small molecule-RNA binding sites in cells
- (2019) Sai Pradeep Velagapudi et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- BAF complex vulnerabilities in cancer demonstrated via structure-based PROTAC design
- (2019) William Farnaby et al. Nature Chemical Biology
- Targeting RNA with Small Molecules: Identification of Selective, RNA-Binding Small Molecules Occupying Drug-Like Chemical Space
- (2019) Noreen F. Rizvi et al. SLAS Discovery
- Long non-coding RNA XIST inhibited breast cancer cell growth, migration, and invasion via miR-155/CDX1 axis
- (2018) Ruinian Zheng et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Modulating PCAF/GCN5 Immune Cell Function through a PROTAC Approach
- (2018) Zuni I. Bassi et al. ACS Chemical Biology
- ScanFold: an approach for genome-wide discovery of local RNA structural elements—applications to Zika virus and HIV
- (2018) Ryan J. Andrews et al. PeerJ
- Defining RNA–Small Molecule Affinity Landscapes Enables Design of a Small Molecule Inhibitor of an Oncogenic Noncoding RNA
- (2017) Sai Pradeep Velagapudi et al. ACS Central Science
- Inforna 2.0: A Platform for the Sequence-Based Design of Small Molecules Targeting Structured RNAs
- (2016) Matthew D. Disney et al. ACS Chemical Biology
- Analysis of secondary structural elements in human microRNA hairpin precursors
- (2016) Biao Liu et al. BMC BIOINFORMATICS
- eIF3d is an mRNA cap-binding protein that is required for specialized translation initiation
- (2016) Amy S. Y. Lee et al. NATURE
- Antisense Oligonucleotides Targeting Influenza A Segment 8 Genomic RNA Inhibit Viral Replication
- (2016) Elzbieta Lenartowicz et al. Nucleic Acid Therapeutics
- Studying a Drug-like, RNA-Focused Small Molecule Library Identifies Compounds That Inhibit RNA Toxicity in Myotonic Dystrophy
- (2015) Suzanne G. Rzuczek et al. ACS Chemical Biology
- Selective Small Molecule Induced Degradation of the BET Bromodomain Protein BRD4
- (2015) Michael Zengerle et al. ACS Chemical Biology
- A Remarkably Simple Hybrid Surfactant-NHC Ligand, Its Gold-Complex, and Application in Micellar Catalysis
- (2015) Andreas Rühling et al. CHEMISTRY-A EUROPEAN JOURNAL
- A Remarkably Simple Class of Imidazolium-Based Lipids and Their Biological Properties
- (2015) Da Wang et al. CHEMISTRY-A EUROPEAN JOURNAL
- eIF3 targets cell-proliferation messenger RNAs for translational activation or repression
- (2015) Amy S. Y. Lee et al. NATURE
- MYC, Metabolism, and Cancer
- (2015) Z. E. Stine et al. Cancer Discovery
- Why is Tanimoto index an appropriate choice for fingerprint-based similarity calculations?
- (2015) Dávid Bajusz et al. Journal of Cheminformatics
- Predicting effective microRNA target sites in mammalian mRNAs
- (2015) Vikram Agarwal et al. eLife
- Early miR-155 upregulation contributes to neuroinflammation in Alzheimer's disease triple transgenic mouse model
- (2014) Joana R. Guedes et al. HUMAN MOLECULAR GENETICS
- Structure of Human RNase L Reveals the Basis for Regulated RNA Decay in the IFN Response
- (2014) Y. Han et al. SCIENCE
- Antisense Oligonucleotide Therapies
- (2014) Kendall S. Frazier TOXICOLOGIC PATHOLOGY
- Covalent Small-Molecule-RNA Complex Formation Enables Cellular Profiling of Small-Molecule-RNA Interactions
- (2013) Lirui Guan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- MiR-155-mediated loss of C/EBPβ shifts the TGF-β response from growth inhibition to epithelial-mesenchymal transition, invasion and metastasis in breast cancer
- (2013) J Johansson et al. ONCOGENE
- Upregulation of miRNA-155 promotes tumour angiogenesis by targeting VHL and is associated with poor prognosis and triple-negative breast cancer
- (2013) W Kong et al. ONCOGENE
- Sweating the Small Stuff
- (2013) Siuwah Tang et al. PANCREAS
- The Oncogenic Role of miR-155 in Breast Cancer
- (2012) S. Mattiske et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Dynamic Change of Chromatin Conformation in Response to Hypoxia Enhances the Expression of GLUT3 (SLC2A3) by Cooperative Interaction of Hypoxia-Inducible Factor 1 and KDM3A
- (2012) I. Mimura et al. MOLECULAR AND CELLULAR BIOLOGY
- Identifying the preferred RNA motifs and chemotypes that interact by probing millions of combinations
- (2012) Tuan Tran et al. Nature Communications
- Analysis of microRNA turnover in mammalian cells following Dicer1 ablation
- (2011) Michael P. Gantier et al. NUCLEIC ACIDS RESEARCH
- Deep Sequencing of MYC DNA-Binding Sites in Burkitt Lymphoma
- (2011) Volkhard Seitz et al. PLoS One
- MicroRNA-155 Functions as an OncomiR in Breast Cancer by Targeting the Suppressor of Cytokine Signaling 1 Gene
- (2010) S. Jiang et al. CANCER RESEARCH
- Egr1 mediates p53-independent c-Myc-induced apoptosis via a noncanonical ARF-dependent transcriptional mechanism
- (2010) D. N. Boone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- RNA and Disease
- (2009) Thomas A. Cooper et al. CELL
- Global Identification of Myc Target Genes Reveals Its Direct Role in Mitochondrial Biogenesis and Its E-Box Usage In Vivo
- (2008) Jonghwan Kim et al. PLoS One
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowCreate your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create Now