Enhancing Methotrexate Delivery in the Brain by Mesoporous Silica Nanoparticles Functionalized with Cell-Penetrating Peptide using in Vivo and ex Vivo Monitoring

Smart Nanomedicine to Enable Crossing Blood–Brain Barrier Delivery of Checkpoint Blockade Antibody for Immunotherapy of Glioma

(2022) Hairong Wang et al.   ACS Nano

Incorporation of Endosomolytic Peptides with Varying Disruption Mechanisms into EGFR-Targeted Protein Conjugates: The Effect on Intracellular Protein Delivery and EGFR Specificity in Breast Cancer Cells

(2022) Rachel M. Lieser et al.   MOLECULAR PHARMACEUTICS

Polysorbate-coated mesoporous silica nanoparticles as an efficient carrier for improved rivastigmine brain delivery

(2022) Samaneh Fateh Basharzad et al.   BRAIN RESEARCH

Research Progress on Nanoplatforms and Nanotherapeutic Strategies in Treating Glioma

(2022) Li Qiao et al.   MOLECULAR PHARMACEUTICS

Enhancing Doxorubicin Delivery in Solid Tumor by Superhydrophobic Amorphous Calcium Carbonate–Doxorubicin Silica Nanoparticles with Focused Ultrasound

(2022) Pei-Hua Chiang et al.   MOLECULAR PHARMACEUTICS

Recent Advancements in the Design of Nanodelivery Systems of siRNA for Cancer Therapy

(2022) Dokkari Nagalaxmi Yadav et al.   Molecular Pharmaceutics

Designing Mesoporous Silica Nanoparticles to Overcome Biological Barriers by Incorporating Targeting and Endosomal Escape

(2021) Miguel Gisbert-Garzarán et al.   ACS Applied Materials & Interfaces

NanoClick: A High Throughput, Target-Agnostic Peptide Cell Permeability Assay

(2021) Andrea Peier et al.   ACS Chemical Biology

Mesoporous Silica Nanoparticles as pH-Responsive Carrier for the Immune-Activating Drug Resiquimod Enhance the Local Immune Response in Mice

(2021) Julia Wagner et al.   ACS Nano

Controlled drug release: On the evolution of physically entrapped drug inside the electrospun poly(lactic-co-glycolic acid) matrix

(2021) Jiaen Wu et al.   JOURNAL OF CONTROLLED RELEASE

A new FTIR method for estimating the firing temperature of ceramic bronze-casting moulds from early China

(2021) Bichen Yan et al.   Scientific Reports

Nanoscale Visualization of Morphological Alteration of Live-Cell Membranes by the Interaction with Oligoarginine Cell-Penetrating Peptides

(2021) Hiroki Ida et al.   ANALYTICAL CHEMISTRY

Mesoporous silica MCM-41 and HMS as advanced drug delivery carriers for bicalutamide

(2021) Teodora Popova et al.   JOURNAL OF DRUG DELIVERY SCIENCE AND TECHNOLOGY

Bioactive injectable composites based on insulin-functionalized silica particles reinforced polymeric hydrogels for potential applications in bone tissue engineering

(2021) Aleksandra Krajcer et al.   JOURNAL OF MATERIALS SCIENCE & TECHNOLOGY

Guanidinylated Cyclic Synthetic Polypeptides Can Effectively Deliver siRNA by Mimicking the Biofunctions of Both Cell-Penetrating Peptides and Nuclear Localization Signal Peptides

(2021) Xinlin Jiang et al.   ACS Macro Letters

Nucleoside transporter-guided cytarabine-conjugated liposomes for intracellular methotrexate delivery and cooperative choriocarcinoma therapy

(2021) Weidong Fei et al.   JOURNAL OF NANOBIOTECHNOLOGY

Engineered Solid Lipid Nanoparticles and Nanostructured Lipid Carriers as New Generations of Blood–Brain Barrier Transmitters

(2021) Mahtab Amiri et al.   ACS Chemical Neuroscience

Amine-β-cyclodextrin-based nanosponges. The role of cyclodextrin amphiphilicity in the imidacloprid uptake

(2021) Gianluca Utzeri et al.   COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS

Emulsions of hydrolyzable oils for the zero-order release of hydrophobic drugs

(2021) Laura Tebcharani et al.   JOURNAL OF CONTROLLED RELEASE

Design of Smart Size‐, Surface‐, and Shape‐Switching Nanoparticles to Improve Therapeutic Efficacy

(2021) Xiaoyun Li et al.   Small

Highly sensitive and selective detection of glutathione using ultrasonic aided synthesis of graphene quantum dots embedded over amine-functionalized silica nanoparticles

(2021) Reshma Kaimal et al.   ULTRASONICS SONOCHEMISTRY

siRNA delivery using intelligent chitosan-capped mesoporous silica nanoparticles for overcoming multidrug resistance in malignant carcinoma cells

(2021) Razieh Heidari et al.   Scientific Reports

Preparation, Optimization, and Evaluation of Methoxy Poly(ethylene glycol)-co-Poly(ε-caprolactone) Nanoparticles Loaded by Rivastigmine for Brain Delivery

(2020) Hamed Mohamadpour et al.   ACS Chemical Neuroscience

Microengineered human blood–brain barrier platform for understanding nanoparticle transport mechanisms

(2020) Song Ih Ahn et al.   Nature Communications

Nanoarchitectured Structure and Surface Biofunctionality of Mesoporous Silica Nanoparticles

(2020) Ranjith Kumar Kankala et al.   ADVANCED MATERIALS

Radiolabeling, In Vitro Cell Uptake, and In Vivo Photodynamic Therapy Potential of Targeted Mesoporous Silica Nanoparticles Containing Zinc Phthalocyanine

(2020) Ozge Er et al.   MOLECULAR PHARMACEUTICS

Simultaneous Single-particle Tracking and Dynamic pH Sensing Reveal Lysosome-targetable Mesoporous Silica Nanoparticles Pathways

(2020) Rong-Lin Chang et al.   ACS Applied Materials & Interfaces

Effect of Colloidal Aqueous Solution of Fullerene (C60) in the Presence of a P-Glycoprotein Inhibitor (Verapamil) on Spatial Memory and Hippocampal Expression of Sirtuin6, SELADIN1, and AQP1 Genes in a Rat Model of Alzheimer’s Disease

(2020) Mehrnoosh Nikpour et al.   ACS Chemical Neuroscience

Natural-Killer-Cell-Inspired Nanorobots with Aggregation-Induced Emission Characteristics for Near-Infrared-II Fluorescence-Guided Glioma Theranostics

(2020) Guanjun Deng et al.   ACS Nano

Investigating the optimum size of nanoparticles for their delivery into the brain assisted by focused ultrasound-induced blood–brain barrier opening

(2020) Seiichi Ohta et al.   Scientific Reports

Angiopep-2 modified lipid-coated mesoporous silica nanoparticles for glioma targeting therapy overcoming BBB

(2020) Jingjing Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Preparation of Sub-50 nm Colloidal Monodispersed Hollow Siloxane-Based Nanoparticles with Controlled Shell Structures

(2020) Tenkai Watanabe et al.   LANGMUIR

Subtoxic cell responses to silica particles with different size and shape

(2020) Markus Kersting et al.   Scientific Reports

Construction of a pH-responsive drug delivery platform based on the hybrid of mesoporous silica and chitosan

(2020) Keliang Zhang et al.   Journal of Saudi Chemical Society

Rational design of metal-organic frameworks to deliver methotrexate for targeted rheumatoid arthritis therapy

(2020) Lina Guo et al.   JOURNAL OF CONTROLLED RELEASE

Enhanced cytotoxic activity of curcumin on cancer cell lines by incorporating into gold/chitosan nanogels

(2019) N. Amanlou et al.   MATERIALS CHEMISTRY AND PHYSICS

NANOSCALE LIPOPHILIC PRODRUGS OF DEXAMETHASONE WITH ENHANCED PHARMACOKINETICS

(2019) Mathilde Lorscheider et al.   MOLECULAR PHARMACEUTICS

Mesoporous Silica‐Based Materials with Bactericidal Properties

(2019) Andrea Bernardos et al.   Small

In Situ Synthesis of Fluorescent Mesoporous Silica–Carbon Dot Nanohybrids Featuring Folate Receptor-Overexpressing Cancer Cell Targeting and Drug Delivery

(2019) Shuai Zhao et al.   Nano-Micro Letters

Red Blood Cell Membrane Bioengineered Zr-89 Labelled Hollow Mesoporous Silica Nanosphere for Overcoming Phagocytosis

(2019) Jun Young Lee et al.   Scientific Reports

Reduction of intratumoral brain perfusion by noninvasive transcranial electrical stimulation

(2019) G. Sprugnoli et al.   Science Advances

Amino Acid-functionalized hollow mesoporous silica nanospheres as efficient biocompatible drug carriers for anticancer applications

(2019) Nasim Ezzati et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

New Advances in In Vivo Applications of Gated Mesoporous Silica as Drug Delivery Nanocarriers

(2019) Alba García‐Fernández et al.   Small

Gold modified polydopamine coated mesoporous silica nano-structures for synergetic chemo-photothermal effect

(2018) Nahla Rahoui et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Amine decorated 2d hexagonal and 3d cubic mesoporous silica nanoparticles: A comprehensive dissolution kinetic study in simulated and biorelevant media

(2018) Priya Shah et al.   JOURNAL OF DISPERSION SCIENCE AND TECHNOLOGY

Supersaturation Potential of Ordered Mesoporous Silica Delivery Systems. Part 1: Dissolution Performance and Drug Membrane Transport Rates

(2018) Tahnee Jade Dening et al.   MOLECULAR PHARMACEUTICS

Drug Delivery to the Brain across the Blood-Brain Barrier Using Nanomaterials

(2018) Yung-Hao Tsou et al.   Small

Machine Learning To Predict Cell-Penetrating Peptides for Antisense Delivery

(2018) Justin M. Wolfe et al.   ACS Central Science

in vitro- and in vivo Evaluation of Methotrexate-Loaded Hydrogel Nanoparticles Intended to Treat Primary CNS Lymphoma via Intranasal Administration

(2018) Leila Pourtalebi Jahromi et al.   JOURNAL OF PHARMACY AND PHARMACEUTICAL SCIENCES

Brain Delivery of Curcumin Using Solid Lipid Nanoparticles and Nanostructured Lipid Carriers: Preparation, Optimization, and Pharmacokinetic Evaluation

(2018) Soroor Sadegh Malvajerd et al.   ACS Chemical Neuroscience

Mesoporous silica materials: From physico-chemical properties to enhanced dissolution of poorly water-soluble drugs

(2017) Aziz Maleki et al.   JOURNAL OF CONTROLLED RELEASE

Intracellular pH-responsive and rituximab-conjugated mesoporous silica nanoparticles for targeted drug delivery to lymphoma B cells

(2017) Shoubing Zhou et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Cleavable Multifunctional Targeting Mixed Micelles with Sequential pH-Triggered TAT Peptide Activation for Improved Antihepatocellular Carcinoma Efficacy

(2017) Jinming Zhang et al.   MOLECULAR PHARMACEUTICS

Functionalized Lipid–Polymer Hybrid Nanoparticles Mediated Codelivery of Methotrexate and Aceclofenac: A Synergistic Effect in Breast Cancer with Improved Pharmacokinetics Attributes

(2017) Neeraj K. Garg et al.   MOLECULAR PHARMACEUTICS

Dendritic Mesoporous Silica Nanoparticles for pH-Stimuli-Responsive Drug Delivery of TNF-Alpha

(2017) Arne Kienzle et al.   Advanced Healthcare Materials

Effects of N-terminal and C-terminal modification on cytotoxicity and cellular uptake of amphiphilic cell penetrating peptides

(2017) Mehdi Soleymani-Goloujeh et al.   Artificial Cells Nanomedicine and Biotechnology

Increased Nanoparticle Delivery to Brain Tumors by Autocatalytic Priming for Improved Treatment and Imaging

(2016) Liang Han et al.   ACS Nano

Adsorption of Microporous Silica Material (mcm-41) on Graphene Sheet as a Nano-Carrier

(2016) Nasim Shadmani et al.   Journal of Computational and Theoretical Nanoscience

Functionalized Mesoporous Silica Nanoparticle for Levodopa Delivery: A Combination with SWCNTs

(2016) N Shadmani et al.   Journal of Computational and Theoretical Nanoscience

Protein-gold clusters-capped mesoporous silica nanoparticles for high drug loading, autonomous gemcitabine/doxorubicin co-delivery, and in-vivo tumor imaging

(2016) Jonas G. Croissant et al.   JOURNAL OF CONTROLLED RELEASE

Effects of different amounts of APTES on physicochemical and structural properties of amino-functionalized MCM-41-MSNs

(2016) William Alejandro Talavera-Pech et al.   JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY

Mechanism of action of methotrexate in rheumatoid arthritis and the search for biomarkers

(2016) Philip M. Brown et al.   Nature Reviews Rheumatology

Advances in Peptide Functionalization on Mesoporous Silica Nanoparticles for Controlled Drug Release

(2016) Jing-Jing Hu et al.   Small

Feasibility Study of the Permeability and Uptake of Mesoporous Silica Nanoparticles across the Blood-Brain Barrier

(2016) Habib Baghirov et al.   PLoS One

Methotrexate Nanoparticles Prepared with Codendrimer from Polyamidoamine (PAMAM) and Oligoethylene Glycols (OEG) Dendrons: Antitumor Efficacy in Vitro and in Vivo

(2016) Yanna Zhao et al.   Scientific Reports

Protein Adsorption From Biofluids on Silica Nanoparticles: Corona Analysis as a Function of Particle Diameter and Porosity

(2015) Alden M. Clemments et al.   ACS Applied Materials & Interfaces

Dissolution enhancement of a model poorly water-soluble drug, atorvastatin, with ordered mesoporous silica: comparison of MSF with SBA-15 as drug carriers

(2015) Aziz Maleki et al.   Expert Opinion on Drug Delivery

Neuropharmacokinetic evaluation of methotrexate-loaded chitosan nanogels

(2015) Amir Azadi et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Synthesis and characterization of micro-mesoporous MCM-41 using various ionic liquids as co-templates

(2015) Haleh Sanaeishoar et al.   MICROPOROUS AND MESOPOROUS MATERIALS

pH dependent chemical stability and release of methotrexate from a novel nanoceramic carrier

(2015) Sayantan Ray et al.   RSC Advances

Stepwise-Acid-Active Multifunctional Mesoporous Silica Nanoparticles for Tumor-Specific Nucleus-Targeted Drug Delivery

(2014) Ze-Yong Li et al.   ACS Applied Materials & Interfaces

Strategies To Deliver Peptide Drugs to the Brain

(2014) Aikaterini Lalatsa et al.   MOLECULAR PHARMACEUTICS

Noncovalent functionalization of mesoporous silica nanoparticles with amphiphilic peptides

(2014) Melis Sardan et al.   Journal of Materials Chemistry B

Overcoming multidrug resistance of cancer cells by direct intranuclear drug delivery using TAT-conjugated mesoporous silica nanoparticles

(2013) Limin Pan et al.   BIOMATERIALS

Multifunctional Mesoporous Silica Nanoparticles as a Universal Platform for Drug Delivery

(2013) Christian Argyo et al.   CHEMISTRY OF MATERIALS

Exploitation of 3D face-centered cubic mesoporous silica as a carrier for a poorly water soluble drug: Influence of pore size on release rate

(2013) Wenquan Zhu et al.   Materials Science & Engineering C-Materials for Biological Applications

Biodistribution and Pharmacokinetics of EGFR-Targeted Thiolated Gelatin Nanoparticles Following Systemic Administration in Pancreatic Tumor-Bearing Mice

(2013) Jing Xu et al.   MOLECULAR PHARMACEUTICS

Delivery of Small Interfering RNA by Peptide-Targeted Mesoporous Silica Nanoparticle-Supported Lipid Bilayers

(2012) Carlee E. Ashley et al.   ACS Nano

Preparation and optimization of surface-treated methotrexate-loaded nanogels intended for brain delivery

(2012) Amir Azadi et al.   CARBOHYDRATE POLYMERS

Large core-expanded triazatruxene-based discotic liquid crystals: synthesis, characterization and physical properties

(2012) Qun Ye et al.   JOURNAL OF MATERIALS CHEMISTRY

Nuclear-Targeted Drug Delivery of TAT Peptide-Conjugated Monodisperse Mesoporous Silica Nanoparticles

(2012) Limin Pan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Multifunctional PEGylated 2C5-immunoliposomes containing pH-sensitive bonds and TAT peptide for enhanced tumor cell internalization and cytotoxicity

(2011) Erez Koren et al.   JOURNAL OF CONTROLLED RELEASE

3D cubic mesoporous silica microsphere as a carrier for poorly soluble drug carvedilol

(2011) Yanchen Hu et al.   MICROPOROUS AND MESOPOROUS MATERIALS

Targeted Delivery of Cargoes into a Murine Solid Tumor by a Cell-Penetrating Peptide and Cleavable Poly(ethylene glycol) Comodified Liposomal Delivery System via Systemic Administration

(2011) Rui Kuai et al.   MOLECULAR PHARMACEUTICS

Mesoporous Silica Microparticles Enhance the Cytotoxicity of Anticancer Platinum Drugs

(2010) Zhimin Tao et al.   ACS Nano

Inclusion of the poorly water-soluble drug simvastatin in mesocellular foam nanoparticles: Drug loading and release properties

(2010) Yanzhuo Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Impacts of Mesoporous Silica Nanoparticle Size, Pore Ordering, and Pore Integrity on Hemolytic Activity

(2010) Yu-Shen Lin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Cancer-Cell-Specific Induction of Apoptosis Using Mesoporous Silica Nanoparticles as Drug-Delivery Vectors

(2010) Jessica M. Rosenholm et al.   Small

Ethenylene-Bridged Periodic Mesoporous Organosilicas: FromEtoZ

(2009) Carl Vercaemst et al.   CHEMISTRY OF MATERIALS

Peptide Synthesis in Aqueous Environments: The Role of Extreme Conditions on Peptide Bond Formation and Peptide Hydrolysis

(2009) Eduard Schreiner et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Intracellulartransduction using cell-penetrating peptides

(2009) Rupa Sawant et al.   Molecular BioSystems

Colloidal Suspensions of Functionalized Mesoporous Silica Nanoparticles

(2008) Johannes Kobler et al.   ACS Nano

Selective Functionalization of the Outer and Inner Surfaces in Mesoporous Silica Nanoparticles

(2008) Johann Kecht et al.   CHEMISTRY OF MATERIALS

The grafting and release behavior of doxorubincin from Fe3O4@SiO2 core–shell structure nanoparticles via an acid cleaving amide bond: the potential for magnetic targeting drug delivery

(2008) F H Chen et al.   NANOTECHNOLOGY

Mesoporous Silica Nanoparticles for Reducing Hemolytic Activity Towards Mammalian Red Blood Cells

(2008) Igor I. Slowing et al.   Small