Immune response and innervation signatures in aseptic hip implant loosening

Osteoarthritis

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Suppression of wear-particle-induced pro-inflammatory cytokine and chemokine production in macrophages via NF-κB decoy oligodeoxynucleotide: A preliminary report

(2014) Tzu-hua Lin et al.   Acta Biomaterialia

Contributions of human tissue analysis to understanding the mechanisms of loosening and osteolysis in total hip replacement

(2014) Jiri Gallo et al.   Acta Biomaterialia

Exposure of polyethylene particles induces interferon-γ expression in a natural killer T lymphocyte and dendritic cell coculture systemin vitro: A preliminary study

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Characterization of macrophage polarizing cytokines in the aseptic loosening of total hip replacements

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Novel biological strategies for treatment of wear particle-induced periprosthetic osteolysis of orthopaedic implants for joint replacement

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On the inflammatory response in metal-on-metal implants

(2014) Ulrike Dapunt et al.   Journal of Translational Medicine

The role of peripheral nerve fibers and their neurotransmitters in cartilage and bone physiology and pathophysiology

(2014) Susanne Grässel   ARTHRITIS RESEARCH & THERAPY

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Osteolysis around total knee arthroplasty: A review of pathogenetic mechanisms

(2013) J. Gallo et al.   Acta Biomaterialia

Macrophages-Key cells in the response to wear debris from joint replacements

(2013) Christophe Nich et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A

Titanium and zirconia particle-induced pro-inflammatory gene expression in cultured macrophages and osteolysis, inflammatory hyperalgesia and edema in vivo

(2013) G.A. Obando-Pereda et al.   LIFE SCIENCES

RANKL in the osteolysis of AES total ankle replacement implants

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Genetic susceptibility to aseptic loosening following total hip arthroplasty: a systematic review

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Particle disease: Biologic mechanisms of periprosthetic osteolysis in total hip arthroplasty

(2012) Jiri Gallo et al.   Innate Immunity

Synovial inflammation, immune cells and their cytokines in osteoarthritis: a review

(2012) B.J.E. de Lange-Brokaar et al.   OSTEOARTHRITIS AND CARTILAGE

Osteoarthritis as an inflammatory disease (osteoarthritis is not osteoarthrosis!)

(2012) F. Berenbaum   OSTEOARTHRITIS AND CARTILAGE

Comparison of Patient and Surgeon Expectations of Total Hip Arthroplasty

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A role for age-related changes in TGFβ signaling in aberrant chondrocyte differentiation and osteoarthritis

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RANKL synthesized by articular chondrocytes contributes to juxta-articular bone loss in chronic arthritis

(2012) Maria J Martínez-Calatrava et al.   ARTHRITIS RESEARCH & THERAPY

Predictors of excellent early outcome after total hip arthroplasty

(2012) George H Smith et al.   Journal of Orthopaedic Surgery and Research

First appearance and location of catecholaminergic cells during experimental arthritis and elimination by chemical sympathectomy

(2011) Silvia Capellino et al.   ARTHRITIS AND RHEUMATISM

Osteoarthritis: an update with relevance for clinical practice

(2011) Johannes WJ Bijlsma et al.   LANCET

Aseptic Lymphocyte-Dominated Vasculitis-Associated Lesion

(2010) Tyler Steven Watters et al.   AMERICAN JOURNAL OF CLINICAL PATHOLOGY

Serum transforming growth factor-beta 1 is not a robust biomarker of incident and progressive radiographic osteoarthritis at the hip and knee: the Johnston County Osteoarthritis Project

(2010) A.E. Nelson et al.   OSTEOARTHRITIS AND CARTILAGE

Soluble neuropilin-2, a nerve repellent receptor, is increased in rheumatoid arthritis synovium and aggravates sympathetic fiber repulsion and arthritis

(2009) Alexander Fassold et al.   ARTHRITIS AND RHEUMATISM

TGF-β and fibrosis in different organs — molecular pathway imprints

(2009) Dirk Pohlers et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Over-expression of receptor activator of nuclear factor-κB ligand (RANKL), inflammatory cytokines, and chemokines in periprosthetic osteolysis of loosened total hip arthroplasty

(2009) Chen-Ti Wang et al.   BIOMATERIALS

The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments

(2009) S. A. Bustin et al.   CLINICAL CHEMISTRY

Comparative toxicity of 24 manufactured nanoparticles in human alveolar epithelial and macrophage cell lines

(2009) Sophie Lanone et al.   Particle and Fibre Toxicology

Differential upregulation of the three transforming growth factor beta isoforms in human osteoarthritic cartilage

(2008) M Pombo-Suarez et al.   ANNALS OF THE RHEUMATIC DISEASES

Macrophages detoxify the genotoxic and cytotoxic effects of surgical cobalt chrome alloy particles but not quartz particles on human cells in vitro

(2008) I. Papageorgiou et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Failure of serum transforming growth factor-beta (TGF-β1) as a biomarker of radiographic osteoarthritis at the knee and hip: a cross-sectional analysis in the Johnston County Osteoarthritis Project

(2008) A.E. Nelson et al.   OSTEOARTHRITIS AND CARTILAGE

Th1 type lymphocyte reactivity to metals in patients with total hip arthroplasty

(2008) Nadim Hallab et al.   Journal of Orthopaedic Surgery and Research

Expression profiling reveals alternative macrophage activation and impaired osteogenesis in periprosthetic osteolysis

(2007) Panagiotis Koulouvaris et al.   JOURNAL OF ORTHOPAEDIC RESEARCH