Nucleation of Biomolecular Condensates from Finite-Sized Simulations

Long term phase separation dynamics in liquid crystal-enriched microdroplets obtained from binary fluid mixtures

(2023) Mehzabin Patel et al.   Soft Matter

On the role of phase separation in the biogenesis of membraneless compartments

(2022) Andrea Musacchio   EMBO JOURNAL

A conceptual framework for understanding phase separation and addressing open questions and challenges

(2022) Tanja Mittag et al.   MOLECULAR CELL

Droplet Microfluidics for the Label‐Free Extraction of Complete Phase Diagrams and Kinetics of Liquid–Liquid Phase Separation in Finite Volumes

(2022) Alessia Villois et al.   Small

A predictive coarse-grained model for position-specific effects of post-translational modifications

(2021) Theodora Myrto Perdikari et al.   BIOPHYSICAL JOURNAL

Dead or alive: DEAD-box ATPases as regulators of ribonucleoprotein complex condensation

(2021) Karsten Weis   BIOLOGICAL CHEMISTRY

A Data-Driven Hydrophobicity Scale for Predicting Liquid–Liquid Phase Separation of Proteins

(2021) Thomas Dannenhoffer-Lafage et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Martini 3: a general purpose force field for coarse-grained molecular dynamics

(2021) Paulo C. T. Souza et al.   NATURE METHODS

Improved coarse‐grained model for studying sequence dependent phase separation of disordered proteins

(2021) Roshan Mammen Regy et al.   PROTEIN SCIENCE

Arginine multivalency stabilizes protein/ RNA condensates

(2021) Matteo Paloni et al.   PROTEIN SCIENCE

Finite-size shifts in simulated protein droplet phase diagrams

(2021) Daniel Nilsson et al.   JOURNAL OF CHEMICAL PHYSICS

A multi-step nucleation process determines the kinetics of prion-like domain phase separation

(2021) Erik W. Martin et al.   Nature Communications

‘RNA modulation of transport properties and stability in phase-separated condensates

(2021) Andrés R. Tejedor et al.   BIOPHYSICAL JOURNAL

Nucleation landscape of biomolecular condensates

(2021) Shunsuke F. Shimobayashi et al.   NATURE

Accurate model of liquid–liquid phase behavior of intrinsically disordered proteins from optimization of single-chain properties

(2021) Giulio Tesei et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TDP-43 α-helical structure tunes liquid–liquid phase separation and function

(2020) Alexander E. Conicella et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Valence and patterning of aromatic residues determine the phase behavior of prion-like domains

(2020) Erik W. Martin et al.   SCIENCE

Unraveling Molecular Interactions in Liquid–Liquid Phase Separation of Disordered Proteins by Atomistic Simulations

(2020) Matteo Paloni et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Simulation of FUS Protein Condensates with an Adapted Coarse-Grained Model

(2020) Zakarya Benayad et al.   Journal of Chemical Theory and Computation

Molecular Details of Protein Condensates Probed by Microsecond Long Atomistic Simulations

(2020) Wenwei Zheng et al.   JOURNAL OF PHYSICAL CHEMISTRY B

How do intrinsically disordered protein regions encode a driving force for liquid–liquid phase separation?

(2020) Wade Borcherds et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Molecular interactions underlying liquid−liquid phase separation of the FUS low-complexity domain

(2019) Anastasia C. Murthy et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

Modelling nucleation from solution with the string method in the osmotic ensemble

(2018) Chengxiang Liu et al.   MOLECULAR PHYSICS

Sequence determinants of protein phase behavior from a coarse-grained model

(2018) Gregory L. Dignon et al.   PLoS Computational Biology

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural and hydrodynamic properties of an intrinsically disordered region of a germ cell-specific protein on phase separation

(2017) Jacob P. Brady et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Liquid phase condensation in cell physiology and disease

(2017) Yongdae Shin et al.   SCIENCE

Intrinsically disordered linkers determine the interplay between phase separation and gelation in multivalent proteins

(2017) Tyler S Harmon et al.   eLife

Overcoming time scale and finite size limitations to compute nucleation rates from small scale well tempered metadynamics simulations

(2016) Matteo Salvalaglio et al.   JOURNAL OF CHEMICAL PHYSICS

Molecular dynamics simulations of solutions at constant chemical potential

(2015) C. Perego et al.   JOURNAL OF CHEMICAL PHYSICS

Nucleation of NaCl from Aqueous Solution: Critical Sizes, Ion-Attachment Kinetics, and Rates

(2015) Nils E. R. Zimmermann et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Residue-by-Residue View of In Vitro FUS Granules that Bind the C-Terminal Domain of RNA Polymerase II

(2015) Kathleen A. Burke et al.   MOLECULAR CELL

Phase Transition of a Disordered Nuage Protein Generates Environmentally Responsive Membraneless Organelles

(2015) Timothy J. Nott et al.   MOLECULAR CELL

The disordered P granule protein LAF-1 drives phase separation into droplets with tunable viscosity and dynamics

(2015) Shana Elbaum-Garfinkle et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular-dynamics simulations of urea nucleation from aqueous solution

(2014) Matteo Salvalaglio et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Reaching One Single and Stable Critical Cluster through Finite-Sized Systems

(2009) Romain Grossier et al.   CRYSTAL GROWTH & DESIGN