Thorium(IV) triggers ferroptosis through disrupting iron homeostasis and heme metabolism in the liver following oral ingestion

Molecular Imaging of Labile Heme in Living Cells Using a Small Molecule Fluorescent Probe

(2022) Kanta Kawai et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

HOIP modulates the stability of GPx4 by linear ubiquitination

(2022) Kangyun Dong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Estimation of Inhaled Effective Doses of Uranium and Thorium for Workers in Bayan Obo Ore and the Surrounding Public, Inner Mongolia, China

(2021) Yao Zhang et al.   International Journal of Environmental Research and Public Health

Mechanism of thorium-nitrate and thorium-dioxide induced cytotoxicity in normal human lung epithelial cells (WI26): Role of oxidative stress, HSPs and DNA damage

(2021) Sourav Kumar Das et al.   ENVIRONMENTAL POLLUTION

HO-1: A new potential therapeutic target to combat osteoporosis

(2021) Jingmin Che et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

China prepares to test thorium-fuelled nuclear reactor

(2021) Smriti Mallapaty   NATURE

Thorium inhibits human respiratory chain complex IV (cytochrome c oxidase)

(2021) Libing Yu et al.   JOURNAL OF HAZARDOUS MATERIALS

Saussurea lappa root extract ameliorates the hazards effect of thorium induced oxidative stress and neuroendocrine alterations in adult male rats

(2020) Mona Abdel-Rahman et al.   ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH

Transferrin Receptor Is a Specific Ferroptosis Marker

(2020) Huizhong Feng et al.   Cell Reports

Ferroptosis and Cancer: Mitochondria Meet the “Iron Maiden” Cell Death

(2020) Anna Martina Battaglia et al.   Cells

Size-dependent toxicity of ThO2 nanoparticles to green algae Chlorella pyrenoidosa

(2019) Xingxing He et al.   AQUATIC TOXICOLOGY

FSP1 is a glutathione-independent ferroptosis suppressor

(2019) Sebastian Doll et al.   NATURE

Reactive Oxygen Species-Induced Lipid Peroxidation in Apoptosis, Autophagy, and Ferroptosis

(2019) Lian-Jiu Su et al.   Oxidative Medicine and Cellular Longevity

Ferroptosis-inducing agents compromise in vitro human islet viability and function

(2018) Antonio Bruni et al.   Cell Death & Disease

Role of Mitochondria in Ferroptosis

(2018) Minghui Gao et al.   MOLECULAR CELL

Characterization of ferroptosis in murine models of hemochromatosis

(2017) Hao Wang et al.   HEPATOLOGY

Influence of Speciation of Thorium on Toxic Effects to Green Algae Chlorella pyrenoidosa

(2017) Can Peng et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Thorium impact on tobacco root transcriptome

(2017) Kateřina Mazari et al.   JOURNAL OF HAZARDOUS MATERIALS

Neuronal Death After Hemorrhagic Stroke In Vitro and In Vivo Shares Features of Ferroptosis and Necroptosis

(2017) Marietta Zille et al.   STROKE

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

The interaction of actinide and lanthanide ions with hemoglobin and its relevance to human and environmental toxicology

(2016) Amit Kumar et al.   JOURNAL OF HAZARDOUS MATERIALS

Atmospheric thorium pollution and inhalation exposure in the largest rare earth mining and smelting area in China

(2016) Lingqing Wang et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death

(2015) Scott J. Dixon et al.   ACS Chemical Biology

Disruption of iron homeostasis and resultant health effects upon exposure to various environmental pollutants: A critical review

(2015) Wenli Guo et al.   JOURNAL OF ENVIRONMENTAL SCIENCES

Separation of uranium and thorium from rare earths for rare earth production – A review

(2015) Zhaowu Zhu et al.   MINERALS ENGINEERING

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Development of a non-denaturing 2D gel electrophoresis protocol for screening in vivo uranium-protein targets in Procambarus clarkii with laser ablation ICP MS followed by protein identification by HPLC–Orbitrap MS

(2014) Ming Xu et al.   TALANTA

NLRP3 inflammasome activation in d-galactosamine and lipopolysaccharide-induced acute liver failure: Role of heme oxygenase-1

(2013) Seok-Joo Kim et al.   FREE RADICAL BIOLOGY AND MEDICINE

Heme Levels Are Increased in Human Failing Hearts

(2013) Arineh Khechaduri et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Receptor recognition of transferrin bound to lanthanides and actinides: a discriminating step in cellular acquisition of f-block metals

(2013) Gauthier J.-P. Deblonde et al.   Metallomics

The porphyrias: advances in diagnosis and treatment

(2012) M. Balwani et al.   BLOOD

Synthesis, radiometal labeling and in vitro evaluation of a targeted PPIX derivative

(2011) Babak Behnam Azad et al.   APPLIED RADIATION AND ISOTOPES

Decorporation and therapeutic efficacy of liposomal-DTPA against thorium-induced toxicity in the Wistar rat

(2011) Amit Kumar et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Biochemistry, cytogenetics and bioaccumulation in silver catfish (Rhamdia quelen) exposed to different thorium concentrations

(2008) Lizelia M. Correa et al.   AQUATIC TOXICOLOGY

Thorium-induced oxidative stress mediated toxicity in mice and its abrogation by Diethylenetriamine pentaacetate

(2008) Amit Kumar et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Elemental transfer from Chinese soil via the diet to the whole human body

(2008) Hong-da Zhu et al.   JOURNAL OF RADIOLOGICAL PROTECTION