Advances in the synthesis of antiviral agents from carbohydrate-derived chiral pools

Review on molnupiravir as a promising oral drug for the treatment of COVID-19

(2022) Elham Zarenezhad et al.   MEDICINAL CHEMISTRY RESEARCH

Concise synthesis of antiviral drug, molnupiravir by direct coupling of fully protected d-Ribose with cytosine

(2022) Tanmoy Sahoo et al.   TETRAHEDRON LETTERS

Carbohydrate-Based Macromolecular Biomaterials

(2021) Lu Su et al.   CHEMICAL REVIEWS

Report of the National Institutes of Health SARS-CoV-2 Antiviral Therapeutics Summit

(2021) Matthew D Hall et al.   JOURNAL OF INFECTIOUS DISEASES

Anti-Covid-19 Drug Analogues: Synthesis of Novel Pyrimidine Thioglycosides as Antiviral Agents Against SARS-COV-2 and Avian Influenza H5N1 Viruses

(2021) Mamdouh A. Abu-Zaied et al.   ACS Omega

The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health — The latest 2019 novel coronavirus outbreak in Wuhan, China

(2020) David S. Hui et al.   INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES

A new coronavirus associated with human respiratory disease in China

(2020) Fan Wu et al.   NATURE

Subunit Vaccines Against Emerging Pathogenic Human Coronaviruses

(2020) Ning Wang et al.   Frontiers in Microbiology

Anti COVID-19 Drugs: Need for More Clinical Evidence and Global Action

(2020) Zakir Khan et al.   ADVANCES IN THERAPY

Covid-19 induced superimposed bacterial infection

(2020) Mohamed A. Hendaus et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Compassionate Use of Remdesivir for Patients with Severe Covid-19

(2020) Jonathan Grein et al.   NEW ENGLAND JOURNAL OF MEDICINE

Synthetic Advancement of Neuraminidase Inhibitor “Tamiflu”

(2020) Bhagirath Limbani et al.   ChemistrySelect

Favipiravir – a Modern Antiviral Drug: Synthesis and Modifications

(2020) Yulia A. Titova et al.   Chemistry of Heterocyclic Compounds

COVID-19: Drug Targets and Potential Treatments

(2020) Carmen Gil et al.   JOURNAL OF MEDICINAL CHEMISTRY

Improvement of the C-glycosylation Step for the Synthesis of Remdesivir

(2020) Fei Xue et al.   ORGANIC PROCESS RESEARCH & DEVELOPMENT

Advances in the development of entry inhibitors for sialic-acid-targeting viruses

(2020) Rick Heida et al.   DRUG DISCOVERY TODAY

COVID-19: An overview and a clinical update

(2020) Arunkumar Krishnan et al.   World Journal of Clinical Cases

Severe Acute Respiratory Syndrome

(2019) David S.C. Hui et al.   INFECTIOUS DISEASE CLINICS OF NORTH AMERICA

Clinical regimens of favipiravir inhibit Zika virus (ZIKV) replication in the Hollow Fiber Infection Model (HFIM)

(2018) Camilly P. Pires de Mello et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Favipiravir as a potential countermeasure against neglected and emerging RNA viruses

(2018) Leen Delang et al.   ANTIVIRAL RESEARCH

Stereoselective Synthesis of Sofosbuvir through Nucleoside Phosphorylation Controlled by Kinetic Resolution

(2018) Elena Cini et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

A new scalable synthesis of entecavir

(2018) Efthymia G. Gioti et al.   TETRAHEDRON

Coronavirus Susceptibility to the Antiviral Remdesivir (GS-5734) Is Mediated by the Viral Polymerase and the Proofreading Exoribonuclease

(2018) Maria L. Agostini et al.   mBio

Ebola viral dynamics in nonhuman primates provides insights into virus immuno-pathogenesis and antiviral strategies

(2018) Vincent Madelain et al.   Nature Communications

Favipiravir inhibits in vitro Usutu virus replication and delays disease progression in an infection model in mice

(2018) Nidya A. Segura Guerrero et al.   ANTIVIRAL RESEARCH

Discovery and Synthesis of a Phosphoramidate Prodrug of a Pyrrolo[2,1-f][triazin-4-amino] Adenine C-Nucleoside (GS-5734) for the Treatment of Ebola and Emerging Viruses

(2017) Dustin Siegel et al.   JOURNAL OF MEDICINAL CHEMISTRY

Stereoselective Synthesis of Anti-Hepatitis B Drug, Entecavir, through Regio- and Stereoselective Epoxide Cleavage

(2017) Young Eum Hyun et al.   Asian Journal of Organic Chemistry

Biological roles of glycans

(2016) Ajit Varki   GLYCOBIOLOGY

Synthesis and Anti-Influenza Activity of Pyridine, Pyridazine, and Pyrimidine C-Nucleosides as Favipiravir (T-705) Analogues

(2016) Guangyi Wang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Synthetic galactomannans with potent anti-HIV activity

(2015) Davaanyam Budragchaa et al.   CARBOHYDRATE POLYMERS

A new and efficient asymmetric synthesis of oseltamivir phosphate (Tamiflu) from d-glucose

(2015) Boonsong Kongkathip et al.   TETRAHEDRON

A short synthetic pathway via three-component coupling reaction to tamiphosphor possessing anti-influenza activity

(2015) Yi-Wei Lo et al.   TETRAHEDRON

Post-exposure efficacy of Oral T-705 (Favipiravir) against inhalational Ebola virus infection in a mouse model

(2014) Sophie J. Smither et al.   ANTIVIRAL RESEARCH

Macromolecular (pro)drugs in antiviral research

(2014) Anton A. A. Smith et al.   Polymer Chemistry

Favipiravir (T-705), a novel viral RNA polymerase inhibitor

(2013) Yousuke Furuta et al.   ANTIVIRAL RESEARCH

Recent developments in anti-herpesvirus drugs

(2013) H. J. Field et al.   BRITISH MEDICAL BULLETIN

Design, synthesis, and antiviral activity of new 1H-1,2,3-triazole nucleoside ribavirin analogs

(2013) Maria de Lourdes G. Ferreira et al.   MEDICINAL CHEMISTRY RESEARCH

Synthesis of oseltamivir and tamiphosphor from N-acetyl-d-glucosamine

(2013) Chih-An Chen et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Synthesis of acylguanidine zanamivir derivatives as neuraminidase inhibitors and the evaluation of their bio-activities

(2013) Chien-Hung Lin et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A new route toward 2-acetamido-4-O-methyl-2-deoxy-d-mannopyranose from a Ferrier derivative of tri-O-acetyl-d-glucal, which contributes to aldolase-catalyzed synthesis of laninamivir (CS-8958)

(2013) Hayato Okazaki et al.   TETRAHEDRON

Catalytic Asymmetric anti-Selective Nitroaldol Reaction En Route to Zanamivir

(2012) Tatsuya Nitabaru et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Recent Advances in Neuraminidase Inhibitor Development as Anti-influenza Drugs

(2012) Enguang Feng et al.   ChemMedChem

Antiviral strategies in hepatitis C virus infection

(2012) Christoph Sarrazin et al.   JOURNAL OF HEPATOLOGY

Development of Oseltamivir Phosphonate Congeners as Anti-influenza Agents

(2012) Ting-Jen R. Cheng et al.   JOURNAL OF MEDICINAL CHEMISTRY

A concise and practical synthesis of oseltamivir phosphate(Tamiflu) from d-mannose

(2012) Nutthawat Chuanopparat et al.   TETRAHEDRON

Concise synthesis of zanamivir and its C4-thiocarbamido derivatives utilizing a [3+2]-cycloadduct derived from d-glucono-δ-lactone

(2012) Xue-Bin Zhu et al.   TETRAHEDRON

A new and efficient asymmetric synthesis of oseltamivir phosphate (Tamiflu) from d-mannose

(2012) Nutthawat Chuanopparat et al.   TETRAHEDRON LETTERS

Laninamivir octanoate: a new long-acting neuraminidase inhibitor for the treatment of influenza

(2011) Hideyuki Ikematsu et al.   Expert Review of Anti-Infective Therapy

A Practical Synthesis of Zanamivir Phosphonate Congeners with Potent Anti-influenza Activity

(2011) Jiun-Jie Shie et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Carbohydrate chemistry in drug discovery

(2011) M. Carmen Galan et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

A Chemo-Enzymatic Synthesis of β-d-Arabinofuranosyl Purine Nucleosides

(2011) Igor Mikhailopulo et al.   SYNTHESIS-STUTTGART

Laninamivir Prodrug CS-8958, a Long-Acting Neuraminidase Inhibitor, Shows Superior Anti-Influenza Virus Activity after a Single Administration

(2010) S. Kubo et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Click reaction synthesis of carbohydrate derivatives from ristocetin aglycon with antibacterial and antiviral activity

(2010) Gábor Pintér et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Sugar-Based Synthesis of Tamiflu and Its Inhibitory Effects on Cell Secretion

(2010) Jimei Ma et al.   CHEMISTRY-A EUROPEAN JOURNAL

Current Advances in Anti-Influenza Therapy

(2010) R. Saladino et al.   CURRENT MEDICINAL CHEMISTRY

Respiratory syncytial virus disease: update on treatment and prevention

(2010) Leonard R Krilov   Expert Review of Anti-Infective Therapy

A Synthesis of Oseltamivir (Tamiflu) Starting fromd-Mannitol

(2010) Ji S. Ko et al.   JOURNAL OF ORGANIC CHEMISTRY

Synthesis and Transdermal Penetration of Stavudine-5s-Esters

(2010) Estee-Marie Holmes et al.   Medicinal Chemistry

Potential of carbohydrate-binding agents as therapeutics against enveloped viruses

(2010) K. O. François et al.   MEDICINAL RESEARCH REVIEWS

Recent advances in anti-HIV natural products

(2010) Inder Pal Singh et al.   NATURAL PRODUCT REPORTS

New chemo-enzymatic route toward N-acetylneuraminic acid derivatives with alkyl groups at C-7 hydroxyl group

(2010) Jordi Calveras et al.   TETRAHEDRON

An efficient synthesis of oseltamivir phosphate (Tamiflu) via a metal-mediated domino reaction and ring-closing metathesis

(2010) Pawinee Wichienukul et al.   TETRAHEDRON LETTERS

Comparison of the Effectiveness of Zanamivir and Oseltamivir against Influenza A/H1N1, A/H3N2, and B

(2009) Naoki Kawai et al.   CLINICAL INFECTIOUS DISEASES

Huisgen Cycloaddition Reaction ofC-Alkynyl Ribosides under Micellar Catalysis: Synthesis of Ribavirin Analogues

(2009) Ramzi Aït Youcef et al.   JOURNAL OF ORGANIC CHEMISTRY

In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

(2009) Yasushi Itoh et al.   NATURE

Efficient Formal Synthesis of Oseltamivir Phosphate (Tamiflu) with Inexpensived-Ribose as the Starting Material

(2009) Hiroshi Osato et al.   ORGANIC LETTERS

Efficient Asymmetric Synthesis of Oseltamivir from d-Mannitol

(2009) Tadakatsu Mandai et al.   SYNLETT

Synthesis and antiviral activity of azoles obtained from carbohydrates

(2008) José Sebastián Barradas et al.   CARBOHYDRATE RESEARCH

DirectC-Glycosylation by Indium-Mediated Alkynylation on Sugar Anomeric Position

(2008) Nadège Lubin-Germain et al.   ORGANIC LETTERS