Dissecting mechanisms of mouse embryonic stem cells heterogeneity through a model-based analysis of transcription factor dynamics

Image-based quantification and mathematical modeling of spatial heterogeneity in ESC colonies

(2015) Maria Herberg et al.   CYTOMETRY PART A

Computational modelling of embryonic stem-cell fate control

(2015) M. Herberg et al.   DEVELOPMENT

Network plasticity of pluripotency transcription factors in embryonic stem cells

(2015) Adam Filipczyk et al.   NATURE CELL BIOLOGY

Transcription factor heterogeneity in pluripotent stem cells: a stochastic advantage

(2014) M.-E. Torres-Padilla et al.   DEVELOPMENT

Stochastic NANOG fluctuations allow mouse embryonic stem cells to explore pluripotency

(2014) Elsa Abranches et al.   DEVELOPMENT

Elucidating functional heterogeneity in hematopoietic progenitor cells: A combined experimental and modeling approach

(2014) Enrica Bach et al.   EXPERIMENTAL HEMATOLOGY

Dynamic Heterogeneity and DNA Methylation in Embryonic Stem Cells

(2014) Zakary S. Singer et al.   MOLECULAR CELL

Mapping the route from naive pluripotency to lineage specification

(2014) T. Kalkan et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

A Model-Based Analysis of Culture-Dependent Phenotypes of mESCs

(2014) Maria Herberg et al.   PLoS One

A competitive protein interaction network buffers Oct4-mediated differentiation to promote pluripotency in embryonic stem cells

(2013) S. Munoz Descalzo et al.   Molecular Systems Biology

Generation and Characterization of a Novel Mouse Embryonic Stem Cell Line with a Dynamic Reporter of Nanog Expression

(2013) Elsa Abranches et al.   PLoS One

Imaging, quantification and visualization of spatio-temporal patterning in mESC colonies under different culture conditions

(2012) N. Scherf et al.   BIOINFORMATICS

The Transcriptional and Epigenomic Foundations of Ground State Pluripotency

(2012) Hendrik Marks et al.   CELL

Predicting stem cell fate changes by differential cell cycle progression patterns

(2012) M. Roccio et al.   DEVELOPMENT

Primitive Endoderm Differentiates via a Three-Step Mechanism Involving Nanog and RTK Signaling

(2011) Stephen Frankenberg et al.   DEVELOPMENTAL CELL

On the symmetry of siblings: automated single-cell tracking to quantify the behavior of hematopoietic stem cells in a biomimetic setup

(2011) Nico Scherf et al.   EXPERIMENTAL HEMATOLOGY

Inhibition of glycogen synthase kinase-3 alleviates Tcf3 repression of the pluripotency network and increases embryonic stem cell resistance to differentiation

(2011) Jason Wray et al.   NATURE CELL BIOLOGY

The ground state of pluripotency

(2010) Jason Wray et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Nanog Variability and Pluripotency Regulation of Embryonic Stem Cells - Insights from a Mathematical Model Analysis

(2010) Ingmar Glauche et al.   PLoS One

Functional Heterogeneity of Embryonic Stem Cells Revealed through Translational Amplification of an Early Endodermal Transcript

(2010) Maurice A. Canham et al.   PLOS BIOLOGY

Nanog Is the Gateway to the Pluripotent Ground State

(2009) Jose Silva et al.   CELL

A novel view on stem cell development: analysing the shape of cellular genealogies

(2009) I. Glauche et al.   CELL PROLIFERATION

Regulated Fluctuations in Nanog Expression Mediate Cell Fate Decisions in Embryonic Stem Cells

(2009) Tibor Kalmar et al.   PLOS BIOLOGY

Capturing Pluripotency

(2008) Jose Silva et al.   CELL

Dynamic Equilibrium and Heterogeneity of Mouse Pluripotent Stem Cells with Distinct Functional and Epigenetic States

(2008) Katsuhiko Hayashi et al.   Cell Stem Cell

Identification and characterization of subpopulations in undifferentiated ES cell culture

(2008) Y. Toyooka et al.   DEVELOPMENT