Maternal Immune Activation Induced by Prenatal Lipopolysaccharide Exposure Leads to Long-Lasting Autistic-like Social, Cognitive and Immune Alterations in Male Wistar Rats
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Title
Maternal Immune Activation Induced by Prenatal Lipopolysaccharide Exposure Leads to Long-Lasting Autistic-like Social, Cognitive and Immune Alterations in Male Wistar Rats
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 24, Issue 4, Pages 3920
Publisher
MDPI AG
Online
2023-02-15
DOI
10.3390/ijms24043920
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Note: Only part of the references are listed.- Pathogenic Infections during Pregnancy and the Consequences for Fetal Brain Development
- (2022) Sukanta Jash et al. Pathogens
- Cytokines in the Brain and Neuroinflammation: We Didn’t Starve the Fire!
- (2022) Jan Konsman Pharmaceuticals
- Sex Differences in Autism Spectrum Disorder: Diagnostic, Neurobiological, and Behavioral Features
- (2022) Antonio Napolitano et al. Frontiers in Psychiatry
- Systemic maternal inflammation promotes ASD via IL-6 and IFN-gamma
- (2022) Daniel Majerczyk et al. BIOSCIENCE REPORTS
- Anandamide and 2-arachidonoylglycerol differentially modulate autistic-like traits in a genetic model of autism based on FMR1 deletion in rats
- (2022) Sara Schiavi et al. NEUROPSYCHOPHARMACOLOGY
- Missense mutation of Fmr1 results in impaired AMPAR-mediated plasticity and socio-cognitive deficits in mice
- (2021) Marta Prieto et al. Nature Communications
- Maternal immune activation generates anxiety in offspring: A translational meta-analysis
- (2021) Laiana A. Quagliato et al. Translational Psychiatry
- Association of Peripheral Blood Levels of Cytokines With Autism Spectrum Disorder: A Meta-Analysis
- (2021) Huaying Zhao et al. Frontiers in Psychiatry
- Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
- (2021) Filippo Mirabella et al. IMMUNITY
- MCP-1: Function, regulation, and involvement in disease
- (2021) Sanjiv Singh et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Maternal immune activation in rodent models: A systematic review of neurodevelopmental changes in gene expression and epigenetic modulation in the offspring brain
- (2021) Rebecca M. Woods et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Neuroinflammation in autism spectrum disorders: Exercise as a “pharmacological” tool
- (2021) Chrystiane V.A. Toscano et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Intrauterine Viral Infections: Impact of Inflammation on Fetal Neurodevelopment
- (2021) Sourav Ganguli et al. Frontiers in Neuroscience
- IL-13 Ameliorates Neuroinflammation and Promotes Functional Recovery after Traumatic Brain Injury
- (2020) Wanying Miao et al. JOURNAL OF IMMUNOLOGY
- Perinatal exposure to omega-3 fatty acid imbalance leads to early behavioral alterations in rat pups
- (2020) Paola Colucci et al. BEHAVIOURAL BRAIN RESEARCH
- COVID-19 during pregnancy: Potential risk for neurodevelopmental disorders in neonates?
- (2020) Paulo Ricardo Martins-Filho et al. European Journal of Obstetrics & Gynecology and Reproductive Biology
- Exenatide, a GLP‐1 analog, has healing effects on LPS‐induced autism model: Inflammation, oxidative stress, gliosis, cerebral GABA, and serotonin interactions
- (2020) Volkan Solmaz et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- Perinatal supplementation with omega-3 fatty acids corrects the aberrant social and cognitive traits observed in a genetic model of autism based on FMR1 deletion in rats
- (2020) Sara Schiavi et al. NUTRITIONAL NEUROSCIENCE
- Healing autism spectrum disorder with cannabinoids: a neuroinflammatory story
- (2020) Emilia Carbone et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Maternal immune activation-induced PPARγ-dependent dysfunction of microglia associated with neurogenic impairment and aberrant postnatal behaviors in offspring
- (2019) Qiuying Zhao et al. NEUROBIOLOGY OF DISEASE
- Unidirectional opioid-cannabinoid cross-tolerance in the modulation of social play behavior in rats
- (2019) Sara Schiavi et al. PSYCHOPHARMACOLOGY
- The influence of neuroinflammation in Autism Spectrum Disorder
- (2019) Samantha M. Matta et al. BRAIN BEHAVIOR AND IMMUNITY
- Sex-Dependent Effects of Perinatal Inflammation on the Brain: Implication for Neuro-Psychiatric Disorders
- (2019) Maryam Ardalan et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Peripheral Administration of IL-13 Induces Anti-inflammatory Microglial/Macrophage Responses and Provides Neuroprotection in Ischemic Stroke
- (2019) Natalia Kolosowska et al. Neurotherapeutics
- TEMPORARY REMOVAL: IFN-γ: A cytokine at the right time, is in the right place
- (2019) J. Daniel Burke et al. SEMINARS IN IMMUNOLOGY
- Serum cytokine levels in children with spectrum autism disorder: Differences in pro- and anti-inflammatory balance
- (2019) Natalia Karolina Kordulewska et al. JOURNAL OF NEUROIMMUNOLOGY
- Sex‐specific behavioral deficits induced at early life by prenatal exposure to the cannabinoid receptor agonist WIN 55,212‐2 depend on mGlu5 receptor signaling
- (2019) Antonia Manduca et al. BRITISH JOURNAL OF PHARMACOLOGY
- Reward-Related Behavioral, Neurochemical and Electrophysiological Changes in a Rat Model of Autism Based on Prenatal Exposure to Valproic Acid
- (2019) Sara Schiavi et al. Frontiers in Cellular Neuroscience
- Modelling fragile X syndrome in the laboratory setting: A behavioral perspective
- (2018) Francesca Melancia et al. BEHAVIOURAL BRAIN RESEARCH
- Sex specific autistic endophenotypes induced by prenatal exposure to valproic acid involve anandamide signaling
- (2018) Francesca Melancia et al. BRITISH JOURNAL OF PHARMACOLOGY
- Impaired repair of DNA damage is associated with autistic-like traits in rats prenatally exposed to valproic acid
- (2018) Michela Servadio et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Blood-brain barrier regulation in psychiatric disorders
- (2018) John Kealy et al. NEUROSCIENCE LETTERS
- The Impact of Systemic Inflammation on Neurodevelopment
- (2018) Nona M. Jiang et al. TRENDS IN MOLECULAR MEDICINE
- Children With Autism Spectrum Disorder With Regression Exhibit a Different Profile in Plasma Cytokines and Adhesion Molecules Compared to Children Without Such Regression
- (2018) Antonio Gomez-Fernandez et al. Frontiers in Pediatrics
- Immune cells and CNS physiology: Microglia and beyond
- (2018) Geoffrey T. Norris et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Acute in utero exposure to lipopolysaccharide induces inflammation in the pre- and postnatal brain and alters the glial cytoarchitecture in the developing amygdala
- (2017) Elaine O’Loughlin et al. Journal of Neuroinflammation
- Maternal immune activation dysregulation of the fetal brain transcriptome and relevance to the pathophysiology of autism spectrum disorder
- (2017) M V Lombardo et al. MOLECULAR PSYCHIATRY
- N-acetylcysteine Prevents Alcohol Related Neuroinflammation in Rats
- (2017) Ricardo Schneider et al. NEUROCHEMICAL RESEARCH
- Maternal psychological stress-induced developmental disability, neonatal mortality and stillbirth in the offspring of Wistar albino rats
- (2017) Sakthivel Govindaraj et al. PLoS One
- The neurobiology of social play and its rewarding value in rats
- (2016) Louk J.M.J. Vanderschuren et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Altered plasma levels of chemokines in autism and their association with social behaviors
- (2016) Yidong Shen et al. PSYCHIATRY RESEARCH
- The maternal interleukin-17a pathway in mice promotes autism-like phenotypes in offspring
- (2016) G. B. Choi et al. SCIENCE
- Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid
- (2016) M Servadio et al. Translational Psychiatry
- Absence of IFNγ promotes hippocampal plasticity and enhances cognitive performance
- (2016) S Monteiro et al. Translational Psychiatry
- The role of sex-differential biology in risk for autism spectrum disorder
- (2016) Donna M. Werling Biology of Sex Differences
- Modeling autism-relevant behavioral phenotypes in rats and mice
- (2015) Michela Servadio et al. BEHAVIOURAL PHARMACOLOGY
- Distinct roles of the endocannabinoids anandamide and 2-arachidonoylglycerol in social behavior and emotionality at different developmental ages in rats
- (2015) Antonia Manduca et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
- Prenatal zinc prevents communication impairments and BDNF disturbance in a rat model of autism induced by prenatal lipopolysaccharide exposure
- (2015) Thiago B. Kirsten et al. LIFE SCIENCES
- Lipopolysaccharide Exposure Induces Maternal Hypozincemia, and Prenatal Zinc Treatment Prevents Autistic-Like Behaviors and Disturbances in the Striatal Dopaminergic and mTOR Systems of Offspring
- (2015) Thiago Berti Kirsten et al. PLoS One
- Co-operation of TLR4 and raft proteins in LPS-induced pro-inflammatory signaling
- (2014) Agnieszka Płóciennikowska et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Microglia Enhance Neurogenesis and Oligodendrogenesis in the Early Postnatal Subventricular Zone
- (2014) Y. Shigemoto-Mogami et al. JOURNAL OF NEUROSCIENCE
- Cytokine aberrations in autism spectrum disorder: a systematic review and meta-analysis
- (2014) A Masi et al. MOLECULAR PSYCHIATRY
- Gender-Dependent Effects of Maternal Immune Activation on the Behavior of Mouse Offspring
- (2014) Ingrid C. Y. Xuan et al. PLoS One
- Gender differences in emotionality and sociability in children with autism spectrum disorders
- (2014) Alexandra M Head et al. Molecular Autism
- Modulation of Adult Hippocampal Neurogenesis by Early-Life Environmental Challenges Triggering Immune Activation
- (2014) Ksenia Musaelyan et al. NEURAL PLASTICITY
- Sex differences in autism spectrum disorders
- (2013) Donna M. Werling et al. CURRENT OPINION IN NEUROLOGY
- LPS Exposure Increases Maternal Corticosterone Levels, Causes Placental Injury and Increases IL-1Β Levels in Adult Rat Offspring: Relevance to Autism
- (2013) Thiago B. Kirsten et al. PLoS One
- Origin and differentiation of microglia
- (2013) Florent Ginhoux et al. Frontiers in Cellular Neuroscience
- Cytokines and the neurodevelopmental basis of mental illness
- (2013) Udani Ratnayake et al. Frontiers in Neuroscience
- Maternal immune activation by LPS selectively alters specific gene expression profiles of interneuron migration and oxidative stress in the fetus without triggering a fetal immune response
- (2012) Devon B. Oskvig et al. BRAIN BEHAVIOR AND IMMUNITY
- Hypoactivity of the central dopaminergic system and autistic-like behavior induced by a single early prenatal exposure to lipopolysaccharide
- (2012) Thiago B. Kirsten et al. JOURNAL OF NEUROSCIENCE RESEARCH
- How Different Are Girls and Boys Above and Below the Diagnostic Threshold for Autism Spectrum Disorders?
- (2012) Katharina Dworzynski et al. JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY
- Microglial Activation in Young Adults With Autism Spectrum Disorder
- (2012) Katsuaki Suzuki et al. JAMA Psychiatry
- The role of immune dysfunction in the pathophysiology of autism
- (2011) Charity Onore et al. BRAIN BEHAVIOR AND IMMUNITY
- Cytokines and brain excitability
- (2011) Michael A. Galic et al. FRONTIERS IN NEUROENDOCRINOLOGY
- Maternal Care Received by Individual Pups Correlates with Adult CA1 Dendritic Morphology and Synaptic Plasticity in a Sex-Dependent Manner
- (2011) F. N. van Hasselt et al. JOURNAL OF NEUROENDOCRINOLOGY
- Prenatal LPS exposure reduces olfactory perception in neonatal and adult rats
- (2011) Thiago Berti Kirsten et al. PHYSIOLOGY & BEHAVIOR
- A Behavioral Comparison of Male and Female Adults with High Functioning Autism Spectrum Conditions
- (2011) Meng-Chuan Lai et al. PLoS One
- Prenatal Lipopolysaccharide Reduces Social Behavior in Male Offspring
- (2010) Thiago B. Kirsten et al. NEUROIMMUNOMODULATION
- Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research
- (2010) Carol Kilkenny et al. PLOS BIOLOGY
- Monocyte Chemoattractant Protein-1 Plays a Dominant Role in the Chronic Inflammation Observed in Alzheimer's Disease
- (2008) Anna Sokolova et al. BRAIN PATHOLOGY
- Cannabinoid and opioid modulation of social play behavior in adolescent rats: Differential behavioral mechanisms
- (2008) Viviana Trezza et al. EUROPEAN NEUROPSYCHOPHARMACOLOGY
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