Targeting anandamide metabolism rescues core and associated autistic-like symptoms in rats prenatally exposed to valproic acid

Modeling autism-relevant behavioral phenotypes in rats and mice

(2015) Michela Servadio et al.   BEHAVIOURAL PHARMACOLOGY

Effects of prenatal exposure to valproic acid on the development of juvenile-typical social play in rats

(2015) Sarah Raza et al.   BEHAVIOURAL PHARMACOLOGY

Genetic Epidemiology and Insights into Interactive Genetic and Environmental Effects in Autism Spectrum Disorders

(2015) Young Shin Kim et al.   BIOLOGICAL PSYCHIATRY

Distinct roles of the endocannabinoids anandamide and 2-arachidonoylglycerol in social behavior and emotionality at different developmental ages in rats

(2015) Antonia Manduca et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Benefits of agomelatine in behavioral, neurochemical and blood brain barrier alterations in prenatal valproic acid induced autism spectrum disorder

(2015) Hariom Kumar et al.   NEUROCHEMISTRY INTERNATIONAL

Effects of an H3R Antagonist on the Animal Model of Autism Induced by Prenatal Exposure to Valproic Acid

(2015) Diego Baronio et al.   PLoS One

Strain- and context-dependent effects of the anandamide hydrolysis inhibitor URB597 on social behavior in rats

(2014) Antonia Manduca et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Reduction in Ultrasonic Vocalizations in Pups Born to Rapid Eye Movement Sleep Restricted Mothers in Rat Model

(2014) Kamalesh K. Gulia et al.   PLoS One

Subchronic Treatment of Donepezil Rescues Impaired Social, Hyperactive, and Stereotypic Behavior in Valproic Acid-Induced Animal Model of Autism

(2014) Ji-Woon Kim et al.   PLoS One

Oxytocin-Mediated GABA Inhibition During Delivery Attenuates Autism Pathogenesis in Rodent Offspring

(2014) R. Tyzio et al.   SCIENCE

Gene × Environment Interactions in Autism Spectrum Disorders: Role of Epigenetic Mechanisms

(2014) Sylvie Tordjman et al.   Frontiers in Psychiatry

Alterations in the endocannabinoid system in the rat valproic acid model of autism

(2013) D.M. Kerr et al.   BEHAVIOURAL BRAIN RESEARCH

Inhibition of histone deacetylase in utero causes sociability deficits in postnatal mice

(2013) Randal X. Moldrich et al.   BEHAVIOURAL BRAIN RESEARCH

Affective communication in rodents: ultrasonic vocalizations as a tool for research on emotion and motivation

(2013) Markus Wöhr et al.   CELL AND TISSUE RESEARCH

Autism

(2013) Meng-Chuan Lai et al.   LANCET

Targeting the endocannabinoid system in the treatment of fragile X syndrome

(2013) Arnau Busquets-Garcia et al.   NATURE MEDICINE

Simvastatin Treatment Highlights a New Role for the Isoprenoid/Cholesterol Biosynthetic Pathway in the Modulation of Emotional Reactivity and Cognitive Performance in Rats

(2013) Marco Segatto et al.   NEUROPSYCHOPHARMACOLOGY

General developmental health in the VPA-rat model of autism

(2013) Mônica R. Favre et al.   Frontiers in Behavioral Neuroscience

Hyperactivity induced by the dopamine D2/D3 receptor agonist quinpirole is attenuated by inhibitors of endocannabinoid degradation in mice

(2012) María Jesús Luque-Rojas et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Endocannabinoids in Amygdala and Nucleus Accumbens Mediate Social Play Reward in Adolescent Rats

(2012) V. Trezza et al.   JOURNAL OF NEUROSCIENCE

Gestational Valproate Alters BOLD Activation in Response to Complex Social and Primary Sensory Stimuli

(2012) Ada C. Felix-Ortiz et al.   PLoS One

Uncoupling of the endocannabinoid signalling complex in a mouse model of fragile X syndrome

(2012) Kwang-Mook Jung et al.   Nature Communications

Psychiatric comorbidities in asperger syndrome and high functioning autism: diagnostic challenges

(2012) Luigi Mazzone et al.   Annals of General Psychiatry

Altering endocannabinoid neurotransmission at critical developmental ages: impact on rodent emotionality and cognitive performance

(2012) Viviana Trezza et al.   Frontiers in Behavioral Neuroscience

Endocannabinoid Modulation of Dopaminergic Motor Circuits

(2012) Teresa Morera-Herreras et al.   Frontiers in Pharmacology

Social encounter with a novel partner in adolescent rats: Activation of the central endocannabinoid system

(2011) Eva María Marco et al.   BEHAVIOURAL BRAIN RESEARCH

The endocannabinoid system in the regulation of emotions throughout lifespan: a discussion on therapeutic perspectives

(2011) Eva M Marco et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Cannabinoids and emotionality: a neuroanatomical perspective

(2011) R.J. McLaughlin et al.   NEUROSCIENCE

mGluR5-Antagonist Mediated Reversal of Elevated Stereotyped, Repetitive Behaviors in the VPA Model of Autism

(2011) Mili V. Mehta et al.   PLoS One

Variation in the human cannabinoid receptor CNR1 gene modulates gaze duration for happy faces

(2011) Bhismadev Chakrabarti et al.   Molecular Autism

Validating γ Oscillations and Delayed Auditory Responses as Translational Biomarkers of Autism

(2010) Michael J. Gandal et al.   BIOLOGICAL PSYCHIATRY

A male with fetal valproate syndrome and autism

(2010) P Gail Williams et al.   DEVELOPMENTAL MEDICINE AND CHILD NEUROLOGY

Chronic URB597 treatment at adulthood reverted most depressive-like symptoms induced by adolescent exposure to THC in female rats

(2010) N. Realini et al.   NEUROPHARMACOLOGY

Abnormal mGlu 5 Receptor/Endocannabinoid Coupling in Mice Lacking FMRP and BC1 RNA

(2010) Mauro Maccarrone et al.   NEUROPSYCHOPHARMACOLOGY

Behavioral and molecular changes in the mouse in response to prenatal exposure to the anti-epileptic drug valproic acid

(2010) F.I. Roullet et al.   NEUROSCIENCE

Species differences in cannabinoid receptor 2 (CNR2gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands

(2009) Q.-R. Liu et al.   GENES BRAIN AND BEHAVIOR

Psychiatric Disorders in Children With Autism Spectrum Disorders: Prevalence, Comorbidity, and Associated Factors in a Population-Derived Sample

(2009) Emily Simonoff et al.   JOURNAL OF THE AMERICAN ACADEMY OF CHILD AND ADOLESCENT PSYCHIATRY

Interactions between environmental aversiveness and the anxiolytic effects of enhanced cannabinoid signaling by FAAH inhibition in rats

(2009) J. Haller et al.   PSYCHOPHARMACOLOGY

Cannabinoid and opioid modulation of social play behavior in adolescent rats: Differential behavioral mechanisms

(2008) Viviana Trezza et al.   EUROPEAN NEUROPSYCHOPHARMACOLOGY

Regulation of CB1cannabinoid receptor internalization by a promiscuous phosphorylation-dependent mechanism

(2008) Tanya L. Daigle et al.   JOURNAL OF NEUROCHEMISTRY

Cannabinoid Modulation of Amygdala Reactivity to Social Signals of Threat in Humans

(2008) K. L. Phan et al.   JOURNAL OF NEUROSCIENCE

Divergent Effects of Anandamide Transporter Inhibitors with Different Target Selectivity on Social Play Behavior in Adolescent Rats

(2008) V. Trezza et al.   JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS

Methylphenidate Disrupts Social Play Behavior in Adolescent Rats

(2008) Louk J M J Vanderschuren et al.   NEUROPSYCHOPHARMACOLOGY

Unusual Repertoire of Vocalizations in the BTBR T+tf/J Mouse Model of Autism

(2008) Maria Luisa Scattoni et al.   PLoS One

Gender-specific behavioral and immunological alterations in an animal model of autism induced by prenatal exposure to valproic acid

(2008) Tomasz Schneider et al.   PSYCHONEUROENDOCRINOLOGY

Reduced anxiety-like behaviour induced by genetic and pharmacological inhibition of the endocannabinoid-degrading enzyme fatty acid amide hydrolase (FAAH) is mediated by CB1 receptors

(2007) Fabricio A. Moreira et al.   NEUROPHARMACOLOGY