The utility and caveat of split-GAL4s in the study of neurodegeneration

Single-cell genomic profiling of human dopamine neurons identifies a population that selectively degenerates in Parkinson’s disease

(2022) Tushar Kamath et al.   NATURE NEUROSCIENCE

Maintenance of mitochondrial integrity in midbrain dopaminergic neurons governed by a conserved developmental transcription factor

(2022) Federico Miozzo et al.   Nature Communications

Neocortical Lewy Body Pathology Parallels Parkinson's Dementia, but Not Always

(2022) W. R. Wayne Martin et al.   ANNALS OF NEUROLOGY

Transsynaptic mapping of Drosophila mushroom body output neurons

(2021) Kristin M Scaplen et al.   eLife

Loss of p21-activated kinase Mbt/PAK4 causes Parkinson-like phenotypes in Drosophila

(2021) Stephanie M Pütz et al.   Disease Models & Mechanisms

SciPy 1.0: fundamental algorithms for scientific computing in Python

(2020) Pauli Virtanen et al.   NATURE METHODS

Genetic Reagents for Making Split-GAL4 Lines inDrosophila

(2018) Heather Dionne et al.   GENETICS

Parallel roles of transcription factors dFOXO and FER2 in the development and maintenance of dopaminergic neurons

(2018) Damla Tas et al.   PLoS Genetics

Genetic Reagents for Making Split-GAL4 Lines inDrosophila

(2018) Heather Dionne et al.   GENETICS

Modeling Parkinson’s Disease in Drosophila: What Have We Learned for Dominant Traits?

(2018) Yulan Xiong et al.   Frontiers in Neurology

Selective neuronal vulnerability in Parkinson disease

(2017) D. James Surmeier et al.   NATURE REVIEWS NEUROSCIENCE

A new brain dopamine-deficientDrosophilaand its pharmacological and genetic rescue

(2016) K. Cichewicz et al.   GENES BRAIN AND BEHAVIOR

Hexameric GFP and mCherry Reporters for theDrosophilaGAL4, Q, and LexA Transcription Systems

(2014) Harold K. Shearin et al.   GENETICS

A Conserved Role for p48 Homologs in Protecting Dopaminergic Neurons from Oxidative Stress

(2014) Peter Bou Dib et al.   PLoS Genetics

The neuronal architecture of the mushroom body provides a logic for associative learning

(2014) Yoshinori Aso et al.   eLife

A Single Dopamine Pathway Underlies Progressive Locomotor Deficits in a Drosophila Model of Parkinson Disease

(2013) Thomas Riemensperger et al.   Cell Reports

Neuronal vulnerability, pathogenesis, and Parkinson's disease

(2012) David Sulzer et al.   MOVEMENT DISORDERS

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Parkinson's Disease: Genetics and Pathogenesis

(2011) Joshua M. Shulman et al.   Annual Review of Pathology-Mechanisms of Disease

Activation of FoxO by LRRK2 induces expression of proapoptotic proteins and alters survival of postmitotic dopaminergic neuron in Drosophila

(2010) Tomoko Kanao et al.   HUMAN MOLECULAR GENETICS

Gal4 turnover and transcription activation

(2009) Galen A. Collins et al.   NATURE

DrosophilaModels of Neurodegenerative Diseases

(2008) Bingwei Lu et al.   Annual Review of Pathology-Mechanisms of Disease