Oocyte in vitro maturation: physiological basis and application to clinical practice

Present state and future outlook for the application of in vitro oocyte maturation in human infertility treatment

(2022) Rebecca L Krisher   BIOLOGY OF REPRODUCTION

Mammalian cumulus-oocyte complex communication: a dialog through long and short distance messaging

(2022) Mathilde Marchais et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

The Simulated Physiological Oocyte Maturation (SPOM) system in domestic animals: A systematic review

(2022) Gabriela Ramos Leal et al.   THERIOGENOLOGY

Effect of dominant follicle status at the time of retrieval on the clinical outcomes in natural cycle IVF combined with immature oocyte treatment

(2022) Jian Hua Li et al.   Aging-US

Development of children born from IVM versus IVF: 2-year follow-up of a randomized controlled trial

(2022) Lan N Vuong et al.   HUMAN REPRODUCTION

Development of children born after in vitro maturation with a prematuration step versus natural conception: a prospective cohort study

(2022) Duy L. Nguyen et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Oocyte diameter predicts the maturation rate of human immature oocytes collected ex vivo

(2022) S. E. Pors et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Transzonal projections: Essential structures mediating intercellular communication in the mammalian ovarian follicle

(2022) Hugh J. Clarke   MOLECULAR REPRODUCTION AND DEVELOPMENT

Rescue in vitro maturation may increase the pregnancy outcomes among women undergoing intracytoplasmic sperm injection

(2022) Dan-Yu Qin et al.   Frontiers in Endocrinology

Improved maturation competence of ovarian tissue oocytes using a biphasic in vitro maturation system for patients with gynecological malignancy: a study on sibling oocytes

(2021) Anastasia Kirillova et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Epidermal growth factor receptor signaling uncouples germ cells from the somatic follicular compartment at ovulation

(2021) Laleh Abbassi et al.   Nature Communications

Fresh embryo transfer versus freeze-only after in vitro maturation with a pre-maturation step in women with high antral follicle count: a randomized controlled pilot study

(2021) Lan N. Vuong et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Approaches to oocyte meiotic arrest in vitro and impact on oocyte developmental competence

(2021) Dulama Richani et al.   BIOLOGY OF REPRODUCTION

Perspectives on the development and future of oocyte IVM in clinical practice

(2021) Michel De Vos et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

The two-step process of ovarian follicular growth and maturation in mammals can be compared to a fruit ripening where quality depends on the second step

(2021) Marc-André Sirard   BIOLOGY OF REPRODUCTION

In vitro maturation without gonadotropins versus in vitro fertilization with hyperstimulation in women with polycystic ovary syndrome: a non-inferiority randomized controlled trial

(2021) Xiaoying Zheng et al.   HUMAN REPRODUCTION

Positive effects of amphiregulin on human oocyte maturation and its molecular drivers in patients with polycystic ovary syndrome

(2021) Nazli Akin et al.   HUMAN REPRODUCTION

Live birth after in vitro maturation in women with gonadotropin resistance ovary syndrome: report of two cases

(2021) Ho Long Le et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

First birth achieved after fertility preservation using vitrification of in vitro matured oocytes in a woman with breast cancer

(2020) M. Grynberg et al.   ANNALS OF ONCOLOGY

Live births after oocyte in vitro maturation with a prematuration step in women with polycystic ovary syndrome

(2020) Lan N. Vuong et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

In vitro maturation of oocytes for preserving fertility in autoimmune premature ovarian insufficiency

(2020) Michaël Grynberg et al.   FERTILITY AND STERILITY

Priming Before In Vitro Maturation Cycles in Cancer Patients Undergoing Urgent Fertility Preservation: a Randomized Controlled Study

(2020) Charlotte Sonigo et al.   Reproductive Sciences

Ovarian follicular waves during the menstrual cycle: physiologic insights into novel approaches for ovarian stimulation

(2020) Angela Baerwald et al.   FERTILITY AND STERILITY

Live births following fertility preservation using in-vitro maturation of ovarian tissue oocytes

(2020) Ingrid Segers et al.   HUMAN REPRODUCTION

Outcome of in-vitro oocyte maturation in patients with PCOS: does phenotype have an impact?

(2020) Shari Mackens et al.   HUMAN REPRODUCTION

In-vitro maturation of oocytes versus conventional IVF in women with infertility and a high antral follicle count: a randomized non-inferiority controlled trial

(2020) Lan N Vuong et al.   HUMAN REPRODUCTION

Metabolic co-dependence of the oocyte and cumulus cells: essential role in determining oocyte developmental competence

(2020) Dulama Richani et al.   HUMAN REPRODUCTION UPDATE

Prospects of Rescuing Young Eggs for Oncofertility

(2020) Michael J. Bertoldo et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Maternal and neonatal outcome and children’s development after medically assisted reproduction with in-vitro matured oocytes—a systematic review and meta-analysis

(2020) Thomas Strowitzki et al.   HUMAN REPRODUCTION UPDATE

Pregnancy and neonatal outcomes of small follicle–derived blastocyst transfer in modified natural cycle in vitro fertilization

(2019) Shokichi Teramoto et al.   FERTILITY AND STERILITY

Altered cytoplasmic maturation in rescued in vitro matured oocytes

(2019) A Ferrer-Vaquer et al.   HUMAN REPRODUCTION

The effectiveness and safety of in vitro maturation of oocytes versus in vitro fertilization in women with a high antral follicle count

(2019) Vu N A Ho et al.   HUMAN REPRODUCTION

Obstetric and neonatal outcome of ART in patients with polycystic ovary syndrome: IVM of oocytes versus controlled ovarian stimulation

(2019) L Mostinckx et al.   HUMAN REPRODUCTION

Aberrant endometrial steroid receptor expression in in-vitro maturation cycles despite hormonal luteal support: A pilot study

(2019) Carolina Ortega-Hrepich et al.   Reproductive Biology

The proportion of nuclear mature oocytes affects ooplasmic competence of metaphase-II in relation to implantation and live birth with ICSI

(2019) Alessandra Parrella et al.   REPRODUCTIVE BIOMEDICINE ONLINE

DNA methylation and mRNA expression of imprinted genes in blastocysts derived from an improved in vitro maturation method for oocytes from small antral follicles in polycystic ovary syndrome patients

(2019) M D Saenz-de-Juano et al.   HUMAN REPRODUCTION

Biphasic in vitro maturation (CAPA-IVM) specifically improves the developmental capacity of oocytes from small antral follicles

(2019) Flor Sanchez et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Capacitation IVM improves cumulus function and oocyte quality in minimally stimulated mice

(2019) Y. Zhao et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Contribution of rescue in vitro maturation versus double ovarian stimulation in ovarian stimulation cycles to poor prognosis women

(2019) Yingchun Liu et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Recommendations from the international evidence-based guideline for the assessment and management of polycystic ovary syndrome

(2018) Helena J. Teede et al.   FERTILITY AND STERILITY

Hallmarks of Human Small Antral Follicle Development: Implications for Regulation of Ovarian Steroidogenesis and Selection of the Dominant Follicle

(2018) Stine G. Kristensen et al.   Frontiers in Endocrinology

In vitro maturation (IVM) of oocytes in patients with resistant ovary syndrome and in patients with repeated deficient oocyte maturation

(2018) A Galvão et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Live birth rate after human chorionic gonadotropin priming in vitro maturation in women with polycystic ovary syndrome

(2018) V. N. A. Ho et al.   Journal of Ovarian Research

Two-year development of children conceived by IVM: a prospective controlled single-blinded study

(2017) S. Roesner et al.   HUMAN REPRODUCTION

An improved IVM method for cumulus-oocyte complexes from small follicles in polycystic ovary syndrome patients enhances oocyte competence and embryo yield

(2017) F. Sánchez et al.   HUMAN REPRODUCTION

The epidermal growth factor network: role in oocyte growth, maturation and developmental competence

(2017) Dulama Richani et al.   HUMAN REPRODUCTION UPDATE

A pre-in vitro maturation medium containing cumulus oocyte complex ligand-receptor signaling molecules maintains meiotic arrest, supports the cumulus oocyte complex and improves oocyte developmental competence

(2017) Nicolas W. Santiquet et al.   MOLECULAR HUMAN REPRODUCTION

Cumulus Cell Transcripts Transit to the Bovine Oocyte in Preparation for Maturation1

(2016) Angus D. Macaulay et al.   BIOLOGY OF REPRODUCTION

Immature Oocytes from Unprimed Juvenile Mice Become a Valuable Source for Embryo Production When Using C-Type Natriuretic Peptide as Essential Component of Culture Medium

(2016) S. Romero et al.   BIOLOGY OF REPRODUCTION

Nondominant small follicles are a promising source of mature oocytes in modified natural cycle in vitro fertilization and embryo transfer

(2016) Shokichi Teramoto et al.   FERTILITY AND STERILITY

IVM in need of clear definitions

(2016) Giovanni Coticchio   HUMAN REPRODUCTION

The definition of IVM is clear—variations need defining

(2016) Michel De Vos et al.   HUMAN REPRODUCTION

What threshold values of antral follicle count and serum AMH levels should be considered for oocyte cryopreservation afterin vitromaturation?

(2016) C. Sonigo et al.   HUMAN REPRODUCTION

Successful live birth in a woman with resistant ovary syndrome following in vitro maturation of oocytes

(2016) Yu Li et al.   Journal of Ovarian Research

Maturation of Oocytes in Vitro

(2016) Patrick Lonergan et al.   Annual Review of Animal Biosciences

Promotion of EGF receptor signaling improves the quality of low developmental competence oocytes

(2015) Satoshi Sugimura et al.   DEVELOPMENTAL BIOLOGY

Oocyte Induction of EGF Responsiveness in Somatic Cells Is Associated With the Acquisition of Porcine Oocyte Developmental Competence

(2015) Lesley J. Ritter et al.   ENDOCRINOLOGY

In vitro maturation of oocytes is not associated with altered deoxyribonucleic acid methylation patterns in children from in vitro fertilization or intracytoplasmic sperm injection

(2015) Galyna Pliushch et al.   FERTILITY AND STERILITY

Human cumulus-enclosed germinal vesicle oocytes from early antral follicles reveal heterogeneous cellular and molecular features associated with in vitro maturation capacity

(2015) F. Sanchez et al.   HUMAN REPRODUCTION

In vitro maturation (IVM) of oocytes recovered from ovariectomy specimens in the laboratory: a promising “ex vivo” method of oocyte cryopreservation resulting in the first report of an ongoing pregnancy in Europe

(2015) Ingrid Segers et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Cumulin, an Oocyte-secreted Heterodimer of the Transforming Growth Factor-β Family, Is a Potent Activator of Granulosa Cells and Improves Oocyte Quality

(2015) David G. Mottershead et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

In Vitro Maturation and Its Role in Clinical Assisted Reproductive Technology

(2015) May-Tal Sauerbrun-Cutler et al.   OBSTETRICAL & GYNECOLOGICAL SURVEY

Global gene expression in granulosa cells of growing, plateau and atretic dominant follicles in cattle

(2015) Annie Girard et al.   Reproductive Biology and Endocrinology

Reevaluation and evolution of the simulated physiological oocyte maturation system

(2015) R.B. Gilchrist et al.   THERIOGENOLOGY

In Vitro Maturation in Women with vs. without Polycystic Ovarian Syndrome: A Systematic Review and Meta-Analysis

(2015) Charalampos Siristatidis et al.   PLoS One

The Gametic Synapse: RNA Transfer to the Bovine Oocyte1

(2014) Angus D. Macaulay et al.   BIOLOGY OF REPRODUCTION

Effect of Epidermal Growth Factor-Like Peptides on the Metabolism of In Vitro- Matured Mouse Oocytes and Cumulus Cells1

(2014) Dulama Richani et al.   BIOLOGY OF REPRODUCTION

Chromosome constitution of human embryos generated after in vitro maturation including 3-isobutyl-1-methylxanthine in the oocyte collection medium

(2014) C. Spits et al.   HUMAN REPRODUCTION

In vitro maturation as an alternative to standard in vitro fertilization for patients diagnosed with polycystic ovaries: a comparative analysis of fresh, frozen and cumulative cycle outcomes

(2014) M. L. Walls et al.   HUMAN REPRODUCTION

Amphiregulin co-operates with bone morphogenetic protein 15 to increase bovine oocyte developmental competence: effects on gap junction-mediated metabolite supply

(2014) Satoshi Sugimura et al.   MOLECULAR HUMAN REPRODUCTION

Bone Morphogenetic Protein 15 in the Pro-Mature Complex Form Enhances Bovine Oocyte Developmental Competence

(2014) Jaqueline Sudiman et al.   PLoS One

Follicle-stimulating hormone regulates expression and activity of epidermal growth factor receptor in the murine ovarian follicle

(2014) Stephany El-Hayek et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In vitro maturation of oocytes: uncommon indications

(2013) Michael Grynberg et al.   FERTILITY AND STERILITY

Oocyte in vitro maturation in normo-ovulatory women

(2013) Rubens Fadini et al.   FERTILITY AND STERILITY

Heparin and cAMP modulators interact during pre-in vitro maturation to affect mouse and human oocyte meiosis and developmental competence

(2013) H.-t. Zeng et al.   HUMAN REPRODUCTION

First pregnancy and live birth resulting from cryopreserved embryos obtained from in vitro matured oocytes after oophorectomy in an ovarian cancer patient

(2013) E. B. Prasath et al.   HUMAN REPRODUCTION

Mode of oocyte maturation affects EGF-like peptide function and oocyte competence

(2013) D. Richani et al.   MOLECULAR HUMAN REPRODUCTION

PCOS patients can benefit from in vitro maturation (IVM) of oocytes

(2012) Einat Shalom-Paz et al.   European Journal of Obstetrics & Gynecology and Reproductive Biology

Improved implantation and ongoing pregnancy rates after single-embryo transfer with an optimized protocol for in vitro oocyte maturation in women with polycystic ovaries and polycystic ovary syndrome

(2012) Stephen M. Junk et al.   FERTILITY AND STERILITY

In vitro maturation or in vitro fertilization for women with polycystic ovaries? A case–control study of 194 treatment cycles

(2012) Anne-Sophie Gremeau et al.   FERTILITY AND STERILITY

Comparison of the obstetric and perinatal outcomes of children conceived from in vitro or in vivo matured oocytes in in vitro maturation treatments with births from conventional ICSI cycles

(2012) R. Fadini et al.   HUMAN REPRODUCTION

Fertilization, embryo development, and clinical outcome of immature oocytes obtained from natural cycle in vitro fertilization

(2012) Weon-Young Son et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

LH-Receptor Gene Expression in Human Granulosa and Cumulus Cells from Antral and Preovulatory Follicles

(2012) Janni Vikkelsø Jeppesen et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Human antral follicles

(2012) L. Guzman et al.   MOLECULAR HUMAN REPRODUCTION

Effect of hCG priming on embryonic development of immature oocytes collected from unstimulated women with polycystic ovarian syndrome

(2012) Xiaoying Zheng et al.   Reproductive Biology and Endocrinology

Estradiol Promotes and Maintains Cumulus Cell Expression of Natriuretic Peptide Receptor 2 (NPR2) and Meiotic Arrest in Mouse OocytesIn Vitro

(2011) Meijia Zhang et al.   ENDOCRINOLOGY

Clinical outcome of non–hCG-primed oocyte in vitro maturation treatment in patients with polycystic ovaries and polycystic ovary syndrome

(2011) Michel De Vos et al.   FERTILITY AND STERILITY

Anti-mullerian hormone as a predictive marker for the selection of women for oocyte in vitro maturation treatment

(2011) Rubens Fadini et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

Natural cycle IVF/IVM may be more desirable for poor responder patients after failure of stimulated cycles

(2011) Jianhua Li et al.   JOURNAL OF ASSISTED REPRODUCTION AND GENETICS

FSH withdrawal improves developmental competence of oocytes in the bovine model

(2011) Anne-Laure Nivet et al.   REPRODUCTION

Recent insights into oocyte - follicle cell interactions provide opportunities for the development of new approaches to in vitro maturation

(2011) Robert B. Gilchrist   REPRODUCTION FERTILITY AND DEVELOPMENT

Vitrification of in vitro matured oocytes collected from antral follicles at the time of ovarian tissue cryopreservation

(2011) Giovanna Fasano et al.   Reproductive Biology and Endocrinology

Simulated physiological oocyte maturation (SPOM): a novel in vitro maturation system that substantially improves embryo yield and pregnancy outcomes

(2010) F. K. Albuz et al.   HUMAN REPRODUCTION

Mouse Oocytes Enable LH-Induced Maturation of the Cumulus-Oocyte Complex via Promoting EGF Receptor-Dependent Signaling

(2010) You-Qiang Su et al.   MOLECULAR ENDOCRINOLOGY

Parthenogenic Blastocysts Derived from Cumulus-Free In Vitro Matured Human Oocytes

(2010) Sohyun L. McElroy et al.   PLoS One

Effect of different gonadotrophin priming on IVM of oocytes from women with normal ovaries: a prospective randomized study

(2010) R Fadini et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Granulosa Cell Ligand NPPC and Its Receptor NPR2 Maintain Meiotic Arrest in Mouse Oocytes

(2010) M. Zhang et al.   SCIENCE

Cyclic GMP Signaling Is Involved in the Luteinizing Hormone-Dependent Meiotic Maturation of Mouse Oocytes1

(2009) Sergio Vaccari et al.   BIOLOGY OF REPRODUCTION

Cyclic GMP from the surrounding somatic cells regulates cyclic AMP and meiosis in the mouse oocyte

(2009) R. P. Norris et al.   DEVELOPMENT

Clinical outcomes for various causes of infertility with natural-cycle in vitro fertilization combined with in vitro maturation of immature oocytes

(2009) Ye Xu et al.   FERTILITY AND STERILITY

In vitro maturation for patients with repeated in vitro fertilization failure due to “oocyte maturation abnormalities”

(2009) Ariel Hourvitz et al.   FERTILITY AND STERILITY

Contribution of in-vitro maturation in ovarian stimulation cycles of poor-responder patients

(2009) Daniela Paes de Almeida Ferreira Braga et al.   REPRODUCTIVE BIOMEDICINE ONLINE

Natural-cycle in vitro fertilization in poor responder patients: a survey of 500 consecutive cycles

(2008) Mauro Schimberni et al.   FERTILITY AND STERILITY

Effects of cilostamide and forskolin on the meiotic resumption and embryonic development of immature human oocytes

(2008) Y.-m. Shu et al.   HUMAN REPRODUCTION

Gene expression profiling of human oocytes following in vivo or in vitro maturation

(2008) Gayle M. Jones et al.   HUMAN REPRODUCTION

Combining ovarian tissue cryobanking with retrieval of immature oocytes followed by in vitro maturation and vitrification: an additional strategy of fertility preservation

(2007) Jack Y.J. Huang et al.   FERTILITY AND STERILITY