Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV

Mitochondrial COA7 is a heme-binding protein with disulfide reductase activity, which acts in the early stages of complex IV assembly

(2022) Luke E. Formosa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

CHCHD4 (MIA40) and the mitochondrial disulfide relay system

(2021) Hasan Al-Habib et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Architecture and assembly dynamics of the essential mitochondrial chaperone complex TIM9·10·12

(2021) Katharina Weinhäupl et al.   STRUCTURE

Redox-Mediated Regulation of Mitochondrial Biogenesis, Dynamics, and Respiratory Chain Assembly in Yeast and Human Cells

(2021) Stefan Geldon et al.   Frontiers in Cell and Developmental Biology

HIGD2A is required for assembly of the COX3 module of human mitochondrial complex IV

(2020) Daniella H Hock et al.   MOLECULAR & CELLULAR PROTEOMICS

Multiple pathways coordinate assembly of human mitochondrial complex IV and stabilization of respiratory supercomplexes

(2020) Teresa Lobo‐Jarne et al.   EMBO JOURNAL

Cytochrome c oxidase deficiency

(2020) Michele Brischigliaro et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets

(2020) Damian Szklarczyk et al.   NUCLEIC ACIDS RESEARCH

Vectorial Import via a Metastable Disulfide-Linked Complex Allows for a Quality Control Step and Import by the Mitochondrial Disulfide Relay

(2019) Markus Habich et al.   Cell Reports

COX6A2 variants cause a muscle‐specific cytochrome c oxidase deficiency

(2019) Michio Inoue et al.   ANNALS OF NEUROLOGY

Lipid signalling drives proteolytic rewiring of mitochondria by YME1L

(2019) Thomas MacVicar et al.   NATURE

Function of hTim8a in complex IV assembly in neuronal cells provides insight into pathomechanism underlying Mohr-Tranebjærg syndrome

(2019) Yilin Kang et al.   eLife

The mitochondrial TMEM177 associates with COX20 during COX2 biogenesis

(2018) Isotta Lorenzi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Structure of the intact 14-subunit human cytochrome c oxidase

(2018) Shuai Zong et al.   CELL RESEARCH

Mitochondrial cytochrome c oxidase biogenesis: Recent developments

(2018) Alba Timón-Gómez et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

COX16 promotes COX2 metallation and assembly during respiratory complex IV biogenesis

(2018) Abhishek Aich et al.   eLife

Structural Basis of Membrane Protein Chaperoning through the Mitochondrial Intermembrane Space

(2018) Katharina Weinhäupl et al.   CELL

Building the CuAsite of cytochromecoxidase: A complicated, redox-dependent process driven by a surprisingly large complement of accessory proteins

(2017) Kimberly A. Jett et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MR-1S Interacts with PET100 and PET117 in Module-Based Assembly of Human Cytochrome c Oxidase

(2017) Sara Vidoni et al.   Cell Reports

Control of mitochondrial biogenesis and function by the ubiquitin–proteasome system

(2017) Piotr Bragoszewski et al.   Open Biology

Tissue- and species-specific differences in cytochrome c oxidase assembly induced by SURF1 defects

(2016) Nikola Kovářová et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Accessory subunits are integral for assembly and function of human mitochondrial complex I

(2016) David A. Stroud et al.   NATURE

The Perseus computational platform for comprehensive analysis of (prote)omics data

(2016) Stefka Tyanova et al.   NATURE METHODS

The MaxQuant computational platform for mass spectrometry-based shotgun proteomics

(2016) Stefka Tyanova et al.   Nature Protocols

COX7A2L Is a Mitochondrial Complex III Binding Protein that Stabilizes the III2+IV Supercomplex without Affecting Respirasome Formation

(2016) Rafael Pérez-Pérez et al.   Cell Reports

Tim29 is a novel subunit of the human TIM22 translocase and is involved in complex assembly and stability

(2016) Yilin Kang et al.   eLife

Bayesian Deconvolution of Mass and Ion Mobility Spectra: From Binary Interactions to Polydisperse Ensembles

(2015) Michael T. Marty et al.   ANALYTICAL CHEMISTRY

The Ca2+-Dependent Release of the Mia40-Induced MICU1-MICU2 Dimer from MCU Regulates Mitochondrial Ca2+ Uptake

(2015) Carmelina Petrungaro et al.   Cell Metabolism

COA6 is a mitochondrial complex IV assembly factor critical for biogenesis of mtDNA-encoded COX2

(2015) David A. Stroud et al.   HUMAN MOLECULAR GENETICS

Interaction between AIF and CHCHD4 Regulates Respiratory Chain Biogenesis

(2015) Emilie Hangen et al.   MOLECULAR CELL

MITRAC7 Acts as a COX1-Specific Chaperone and Reveals a Checkpoint during Cytochrome c Oxidase Assembly

(2015) Sven Dennerlein et al.   Cell Reports

A Founder Mutation in PET100 Causes Isolated Complex IV Deficiency in Lebanese Individuals with Leigh Syndrome

(2014) Sze Chern Lim et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Human COX20 cooperates with SCO1 and SCO2 to mature COX2 and promote the assembly of cytochrome c oxidase

(2014) Myriam Bourens et al.   HUMAN MOLECULAR GENETICS

Redox sulfur chemistry of the copper chaperone Atox1 is regulated by the enzyme glutaredoxin 1, the reduction potential of the glutathione couple GSSG/2GSH and the availability of Cu(i)

(2014) Jens Brose et al.   Metallomics

Minimal, encapsulated proteomic-sample processing applied to copy-number estimation in eukaryotic cells

(2014) Nils A Kulak et al.   NATURE METHODS

hCOA3 Stabilizes CytochromecOxidase 1 (COX1) and Promotes CytochromecOxidase Assembly in Human Mitochondria

(2013) Paula Clemente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Ubiquitin-Proteasome System Regulates Mitochondrial Intermembrane Space Proteins

(2013) P. Bragoszewski et al.   MOLECULAR AND CELLULAR BIOLOGY

The CRAPome: a contaminant repository for affinity purification–mass spectrometry data

(2013) Dattatreya Mellacheruvu et al.   NATURE METHODS

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

A Mutation in C2orf64 Causes Impaired Cytochrome c Oxidase Assembly and Mitochondrial Cardiomyopathy

(2011) Merei Huigsloot et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Coa3 and Cox14 are essential for negative feedback regulation ofCOX1translation in mitochondria

(2010) David U. Mick et al.   JOURNAL OF CELL BIOLOGY

The Tim8–Tim13 Complex Has Multiple Substrate Binding Sites and Binds Cooperatively to Tim23

(2008) Kristen N. Beverly et al.   JOURNAL OF MOLECULAR BIOLOGY

Mitochondrial copper(I) transfer from Cox17 to Sco1 is coupled to electron transfer

(2008) L. Banci et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA