Enhancer Coamplification and Hijacking Promote Oncogene Expression in Liposarcoma
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Enhancer Coamplification and Hijacking Promote Oncogene Expression in Liposarcoma
Authors
Keywords
-
Journal
CANCER RESEARCH
Volume 83, Issue 9, Pages 1517-1530
Publisher
American Association for Cancer Research (AACR)
Online
2023-02-28
DOI
10.1158/0008-5472.can-22-1858
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The genomic and spatial mobility of extrachromosomal DNA and its implications for cancer therapy
- (2022) Eric van Leen et al. NATURE GENETICS
- Accurate and efficient detection of gene fusions from RNA sequencing data
- (2021) Sebastian Uhrig et al. GENOME RESEARCH
- Oncogenic extrachromosomal DNA functions as mobile enhancers to globally amplify chromosomal transcription
- (2021) Yanfen Zhu et al. CANCER CELL
- Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
- (2021) Leonie Smeenk et al. Cancer Discovery
- Genome-wide detection of enhancer-hijacking events from chromatin interaction data in rearranged genomes
- (2021) Xiaotao Wang et al. NATURE METHODS
- Enhancers in disease: molecular basis and emerging treatment strategies
- (2021) Annique Claringbould et al. TRENDS IN MOLECULAR MEDICINE
- 3D genome alterations associated with dysregulated HOXA13 expression in high-risk T-lineage acute lymphoblastic leukemia
- (2021) Lu Yang et al. Nature Communications
- Enhancer hijacking drives oncogenic BCL11B expression in lineage ambiguous stem cell leukemia
- (2021) Lindsey E Montefiori et al. Cancer Discovery
- Epigenomic landscape and 3D genome structure in pediatric high-grade glioma
- (2021) Juan Wang et al. Science Advances
- A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer
- (2021) Yanli Liu et al. Nature Communications
- High-coverage whole-genome analysis of 1220 cancers reveals hundreds of genes deregulated by rearrangement-mediated cis-regulatory alterations
- (2020) Yiqun Zhang et al. Nature Communications
- 13q12.2 deletions in acute lymphoblastic leukemia lead to upregulation of FLT3 through enhancer hijacking
- (2020) Minjun Yang et al. BLOOD
- Oncogenic role of HMGA2 in fusion-negative rhabdomyosarcoma cells
- (2020) Kazutaka Ouchi et al. Cancer Cell International
- High Mobility Group AT-Hook 2 (HMGA2) Oncogenicity in Mesenchymal and Epithelial Neoplasia
- (2020) Uchenna Unachukwu et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Ribbon: Intuitive visualization for complex genomic variation
- (2020) Maria Nattestad et al. BIOINFORMATICS
- A supervised learning framework for chromatin loop detection in genome-wide contact maps
- (2020) Tarik J. Salameh et al. Nature Communications
- Comprehensive analysis of structural variants in breast cancer genomes using single-molecule sequencing
- (2020) Sergey Aganezov et al. GENOME RESEARCH
- Enhancer hijacking determines extrachromosomal circular MYCN amplicon architecture in neuroblastoma
- (2020) Konstantin Helmsauer et al. Nature Communications
- Enhancer hijacking activates oncogenic transcription factor NR4A3 in acinic cell carcinomas of the salivary glands
- (2019) Florian Haller et al. Nature Communications
- Bromodomain and extraterminal proteins foster the core transcriptional regulatory programs and confer vulnerability in liposarcoma
- (2019) Ye Chen et al. Nature Communications
- Assembly of long, error-prone reads using repeat graphs
- (2019) Mikhail Kolmogorov et al. NATURE BIOTECHNOLOGY
- Integrated paired-end enhancer profiling and whole-genome sequencing reveals recurrent CCNE1 and IGF2 enhancer hijacking in primary gastric adenocarcinoma
- (2019) Wen Fong Ooi et al. GUT
- Functional Enhancers Shape Extrachromosomal Oncogene Amplifications
- (2019) Andrew R. Morton et al. CELL
- Circular ecDNA promotes accessible chromatin and high oncogene expression
- (2019) Sihan Wu et al. NATURE
- MT1G serves as a tumor suppressor in hepatocellular carcinoma by interacting with p53
- (2019) Yingchao Wang et al. Oncogenesis
- Minimap2: pairwise alignment for nucleotide sequences
- (2018) Heng Li BIOINFORMATICS
- A Somatically Acquired Enhancer of the Androgen Receptor Is a Noncoding Driver in Advanced Prostate Cancer
- (2018) David Y. Takeda et al. CELL
- Structural Alterations Driving Castration-Resistant Prostate Cancer Revealed by Linked-Read Genome Sequencing
- (2018) Srinivas R. Viswanathan et al. CELL
- SvABA: genome-wide detection of structural variants and indels by local assembly
- (2018) Jeremiah A. Wala et al. GENOME RESEARCH
- Accurate detection of complex structural variations using single-molecule sequencing
- (2018) Fritz J. Sedlazeck et al. NATURE METHODS
- Structural variation in the 3D genome
- (2018) Malte Spielmann et al. NATURE REVIEWS GENETICS
- Integrative detection and analysis of structural variation in cancer genomes
- (2018) Jesse R. Dixon et al. NATURE GENETICS
- MT1G is Silenced by DNA Methylation and Contributes to the Pathogenesis of Hepatocellular Carcinoma
- (2018) Ju-deng Zeng et al. Journal of Cancer
- Early-Stage Metastasis Requires Mdm2 and Not p53 Gain of Function
- (2017) Paula M. Hauck et al. MOLECULAR CANCER RESEARCH
- Transient structural variations have strong effects on quantitative traits and reproductive isolation in fission yeast
- (2017) Daniel C. Jeffares et al. Nature Communications
- Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
- (2016) Joachim Weischenfeldt et al. NATURE GENETICS
- An oncogenic MYB feedback loop drives alternate cell fates in adenoid cystic carcinoma
- (2016) Yotam Drier et al. NATURE GENETICS
- SORBS1 suppresses tumor metastasis and improves the sensitivity of cancer to chemotherapy drug
- (2016) Lele Song et al. Oncotarget
- Increased H3K9me3 drives dedifferentiated phenotype via KLF6 repression in liposarcoma
- (2015) Emily Z. Keung et al. JOURNAL OF CLINICAL INVESTIGATION
- Prognostic value of HMGA2, CDK4 and JUN amplification in well-differentiated and dedifferentiated liposarcomas
- (2015) Esma Saâda-Bouzid et al. MODERN PATHOLOGY
- Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
- (2015) Xiaoyang Zhang et al. NATURE GENETICS
- An ultra-low-input native ChIP-seq protocol for genome-wide profiling of rare cell populations
- (2015) Julie Brind’Amour et al. Nature Communications
- MDM2 Copy Numbers in Well-Differentiated and Dedifferentiated Liposarcoma
- (2014) Patrick L. Ware et al. AMERICAN JOURNAL OF CLINICAL PATHOLOGY
- The Architecture and Evolution of Cancer Neochromosomes
- (2014) Dale W. Garsed et al. CANCER CELL
- A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
- (2014) Suhas S.P. Rao et al. CELL
- A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia
- (2014) Stefan Gröschel et al. CELL
- Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
- (2014) Paul A. Northcott et al. NATURE
- LUMPY: a probabilistic framework for structural variant discovery
- (2014) Ryan M Layer et al. GENOME BIOLOGY
- Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
- (2013) Warren A. Whyte et al. CELL
- Role of SWI/SNF in acute leukemia maintenance and enhancer-mediated Myc regulation
- (2013) J. Shi et al. GENES & DEVELOPMENT
- DELLY: structural variant discovery by integrated paired-end and split-read analysis
- (2012) T. Rausch et al. BIOINFORMATICS
- STAR: ultrafast universal RNA-seq aligner
- (2012) Alexander Dobin et al. BIOINFORMATICS
- Long-term results of a phase 2 study of neoadjuvant chemotherapy and radiotherapy in the management of high-risk, high-grade, soft tissue sarcomas of the extremities and body wall
- (2010) William G. Kraybill et al. CANCER
- An experimental model for the study of well-differentiated and dedifferentiated liposarcoma; deregulation of targetable tyrosine kinase receptors
- (2010) Tingsheng Peng et al. LABORATORY INVESTIGATION
- Circos: An information aesthetic for comparative genomics
- (2009) M. Krzywinski et al. GENOME RESEARCH
- Gene Regulation in the Third Dimension
- (2008) J. Dekker SCIENCE
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started