Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
Published 2016 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking
Authors
Keywords
-
Journal
NATURE GENETICS
Volume 49, Issue 1, Pages 65-74
Publisher
Springer Nature
Online
2016-11-22
DOI
10.1038/ng.3722
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Activation of proto-oncogenes by disruption of chromosome neighborhoods
- (2016) D. Hnisz et al. SCIENCE
- Fast and efficient QTL mapper for thousands of molecular phenotypes
- (2015) Halit Ongen et al. BIOINFORMATICS
- FourCSeq: analysis of 4C sequencing data
- (2015) Felix A. Klein et al. BIOINFORMATICS
- Population Variation and Genetic Control of Modular Chromatin Architecture in Humans
- (2015) Sebastian M. Waszak et al. CELL
- Disruptions of Topological Chromatin Domains Cause Pathogenic Rewiring of Gene-Enhancer Interactions
- (2015) Darío G. Lupiáñez et al. CELL
- IGF2 signaling and regulation in cancer
- (2015) Jurriaan Brouwer-Visser et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Structural and functional diversity of Topologically Associating Domains
- (2015) Job Dekker et al. FEBS LETTERS
- Brg1 promotes both tumor-suppressive and oncogenic activities at distinct stages of pancreatic cancer formation
- (2015) Nilotpal Roy et al. GENES & DEVELOPMENT
- A cell-based model system links chromothripsis with hyperploidy
- (2015) B. R. Mardin et al. Molecular Systems Biology
- Telomerase activation by genomic rearrangements in high-risk neuroblastoma
- (2015) Martin Peifer et al. NATURE
- Data analysis: Create a cloud commons
- (2015) Lincoln D. Stein et al. NATURE
- Integrative analysis of 111 reference human epigenomes
- (2015) Anshul Kundaje et al. NATURE
- Non-coding recurrent mutations in chronic lymphocytic leukaemia
- (2015) Xose S. Puente et al. NATURE
- TERT rearrangements are frequent in neuroblastoma and identify aggressive tumors
- (2015) Linda J Valentijn et al. NATURE GENETICS
- Identification of focally amplified lineage-specific super-enhancers in human epithelial cancers
- (2015) Xiaoyang Zhang et al. NATURE GENETICS
- Recurrent somatic mutations in regulatory regions of human cancer genomes
- (2015) Collin Melton et al. NATURE GENETICS
- CTCF establishes discrete functional chromatin domains at theHoxclusters during differentiation
- (2015) Varun Narendra et al. SCIENCE
- When Deletions Gain Functions: Commandeering Epigenetic Mechanisms
- (2014) Justin Chen et al. CANCER CELL
- The Somatic Genomic Landscape of Chromophobe Renal Cell Carcinoma
- (2014) Caleb F. Davis et al. CANCER CELL
- A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
- (2014) Suhas S.P. Rao et al. CELL
- A Single Oncogenic Enhancer Rearrangement Causes Concomitant EVI1 and GATA2 Deregulation in Leukemia
- (2014) Stefan Gröschel et al. CELL
- Mapping the Shh long-range regulatory domain
- (2014) E. Anderson et al. DEVELOPMENT
- Genomics of uterine leiomyomas: insights from high-throughput sequencing
- (2014) Miika Mehine et al. FERTILITY AND STERILITY
- Functional and topological characteristics of mammalian regulatory domains
- (2014) O. Symmons et al. GENOME RESEARCH
- Insulin Receptor Substrate-4 Binds to Slingshot-1 Phosphatase and Promotes Cofilin Dephosphorylation
- (2014) Yuta Homma et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Enhancer hijacking activates GFI1 family oncogenes in medulloblastoma
- (2014) Paul A. Northcott et al. NATURE
- Comprehensive molecular profiling of lung adenocarcinoma
- (2014) Eric A. Collisson et al. NATURE
- Identification of genomic alterations in oesophageal squamous cell cancer
- (2014) Yongmei Song et al. NATURE
- Discovery and saturation analysis of cancer genes across 21 tumour types
- (2014) Michael S. Lawrence et al. NATURE
- Genome-wide analysis of noncoding regulatory mutations in cancer
- (2014) Nils Weinhold et al. NATURE GENETICS
- Systematic analysis of noncoding somatic mutations and gene expression alterations across 14 tumor types
- (2014) Nils J Fredriksson et al. NATURE GENETICS
- Oncogenic transformation of diverse gastrointestinal tissues in primary organoid culture
- (2014) Xingnan Li et al. NATURE MEDICINE
- The landscape and therapeutic relevance of cancer-associated transcript fusions
- (2014) K Yoshihara et al. ONCOGENE
- An oncogenic super-enhancer formed through somatic mutation of a noncoding intergenic element
- (2014) M. R. Mansour et al. SCIENCE
- Integrative Genomic Analyses Reveal an Androgen-Driven Somatic Alteration Landscape in Early-Onset Prostate Cancer
- (2013) Joachim Weischenfeldt et al. CANCER CELL
- Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues
- (2013) Jiang Zhu et al. CELL
- Punctuated Evolution of Prostate Cancer Genomes
- (2013) Sylvan C. Baca et al. CELL
- Master Transcription Factors and Mediator Establish Super-Enhancers at Key Cell Identity Genes
- (2013) Warren A. Whyte et al. CELL
- Super-Enhancers in the Control of Cell Identity and Disease
- (2013) Denes Hnisz et al. CELL
- Topology of mammalian developmental enhancers and their regulatory landscapes
- (2013) Wouter de Laat et al. NATURE
- Maternal imprinting at the H19–Igf2 locus maintains adult haematopoietic stem cell quiescence
- (2013) Aparna Venkatraman et al. NATURE
- Mutational landscape and significance across 12 major cancer types
- (2013) Cyriac Kandoth et al. NATURE
- Recurrent somatic alterations of FGFR1 and NTRK2 in pilocytic astrocytoma
- (2013) David T W Jones et al. NATURE GENETICS
- Pan-cancer patterns of somatic copy number alteration
- (2013) Travis I Zack et al. NATURE GENETICS
- Emerging landscape of oncogenic signatures across human cancers
- (2013) Giovanni Ciriello et al. NATURE GENETICS
- Effect of IRS4 Levels on PI 3-Kinase Signalling
- (2013) Gerta Hoxhaj et al. PLoS One
- Mechanisms of FGFR-mediated carcinogenesis
- (2012) Imran Ahmad et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- DELLY: structural variant discovery by integrated paired-end and split-read analysis
- (2012) T. Rausch et al. BIOINFORMATICS
- Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations
- (2012) Tobias Rausch et al. CELL
- Determining long-range chromatin interactions for selected genomic sites using 4C-seq technology: From fixation to computation
- (2012) Erik Splinter et al. METHODS
- The long-range interaction landscape of gene promoters
- (2012) Amartya Sanyal et al. NATURE
- Dissecting the genomic complexity underlying medulloblastoma
- (2012) David T. W. Jones et al. NATURE
- A map of the cis-regulatory sequences in the mouse genome
- (2012) Yin Shen et al. NATURE
- Topological domains in mammalian genomes identified by analysis of chromatin interactions
- (2012) Jesse R. Dixon et al. NATURE
- Spatial partitioning of the regulatory landscape of the X-inactivation centre
- (2012) Elphège P. Nora et al. NATURE
- Massive Genomic Rearrangement Acquired in a Single Catastrophic Event during Cancer Development
- (2011) Philip J. Stephens et al. CELL
- Distinct Types of Tumor-Initiating Cells Form Human Colon Cancer Tumors and Metastases
- (2011) Sebastian M. Dieter et al. Cell Stem Cell
- Genomic inflation factors under polygenic inheritance
- (2011) Jian Yang et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Mapping and analysis of chromatin state dynamics in nine human cell types
- (2011) Jason Ernst et al. NATURE
- BEDTools: a flexible suite of utilities for comparing genomic features
- (2010) Aaron R. Quinlan et al. BIOINFORMATICS
- Transcriptional Enhancers in Animal Development and Evolution
- (2010) Mike Levine CURRENT BIOLOGY
- Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
- (2010) Sven Heinz et al. MOLECULAR CELL
- Signatures of mutation and selection in the cancer genome
- (2010) Graham R. Bignell et al. NATURE
- The landscape of somatic copy-number alteration across human cancers
- (2010) Rameen Beroukhim et al. NATURE
- Independent filtering increases detection power for high-throughput experiments
- (2010) R. Bourgon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genomic copy number determination in cancer cells from single nucleotide polymorphism microarrays based on quantitative genotyping corrected for aneuploidy
- (2009) E. F. Attiyeh et al. GENOME RESEARCH
- A comprehensive catalogue of somatic mutations from a human cancer genome
- (2009) Erin D. Pleasance et al. NATURE
- Complex landscapes of somatic rearrangement in human breast cancer genomes
- (2009) Philip J. Stephens et al. NATURE
- DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome
- (2008) Timothy J. Ley et al. NATURE
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now