GLP-1 agonist Liraglutide prevents MK‑801–induced schizophrenia‑like behaviors and BDNF, CREB, p-CREB, Trk-B expressions in the hippocampus and prefrontal cortex in Balb/c mice

Treating cognitive impairment in schizophrenia with GLP-1RAs: an overview of their therapeutic potential

(2021) Jonathan Flintoff et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Reduction in TNF alpha and oxidative stress by liraglutide: Impact on ketamine-induced cognitive dysfunction and hyperlocomotion in rats

(2021) Amina Ahmed Sedky et al.   LIFE SCIENCES

The GLP-1 receptor agonist liraglutide reverses mania-like alterations and memory deficits induced by D-amphetamine and augments lithium effects in mice: Relevance for bipolar disorder

(2020) Adriano José Maia Chaves Filho et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

The facilitating effect of MK-801 on inhibitory avoidance memory via mTOR signaling in the mouse hippocampus

(2020) Ming-Heng Hsiung et al.   BEHAVIOURAL BRAIN RESEARCH

Tolerance develops toward GLP-1 receptor agonists’ glucose-lowering effect in mice

(2020) Tuuli Sedman et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Quetiapine Attenuates Schizophrenia-Like Behaviors and Demyelination in a MK-801–Induced Mouse Model of Schizophrenia

(2020) Jue He et al.   Frontiers in Psychiatry

The neuroprotection of liraglutide on diabetic cognitive deficits is associated with improved hippocampal synapses and inhibited neuronal apoptosis

(2019) Wenhui Yan et al.   LIFE SCIENCES

Liraglutide Lowers Body Weight Set Point in DIO Rats and its Relationship with Hypothalamic Microglia Activation

(2019) Ting Liao et al.   Obesity

GABA interneurons are the cellular trigger for ketamine’s rapid antidepressant actions

(2019) Danielle M. Gerhard et al.   JOURNAL OF CLINICAL INVESTIGATION

Liraglutide prevents metabolic side-effects and improves recognition and working memory during antipsychotic treatment in rats

(2018) Ilijana Babic et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Liraglutide modulates gut microbiota and reduces NAFLD in obese mice

(2018) GV Moreira et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Prevention of pentylenetetrazole-induced kindling and behavioral comorbidities in mice by levetiracetam combined with the GLP-1 agonist liraglutide: Involvement of brain antioxidant and BDNF upregulating properties

(2018) Alana Gomes de Souza et al.   BIOMEDICINE & PHARMACOTHERAPY

Liraglutide Activates mTORC1 Signaling and AMPA Receptors in Rat Hippocampal Neurons Under Toxic Conditions

(2018) Sung Woo Park et al.   Frontiers in Neuroscience

ω-3PUFAs prevent MK-801-induced cognitive impairment in schizophrenic rats via the CREB/BDNF/TrkB pathway

(2017) Mao-sheng Fang et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

Liraglutide reduces body weight by upregulation of adenylate cyclase 3

(2017) Z Li et al.   Nutrition & Diabetes

Effect of Liraglutide on Corneal Kindling Epilepsy Induced Depression and Cognitive Impairment in Mice

(2016) Prashant Koshal et al.   NEUROCHEMICAL RESEARCH

Exendin-4 antagonizes Aβ1-42-induced attenuation of spatial learning and memory ability

(2016) Xiaohui Wang et al.   Experimental and Therapeutic Medicine

Oral Administration of Sitagliptin Activates CREB and Is Neuroprotective in Murine Model of Brain Trauma

(2016) Brian DellaValle et al.   Frontiers in Pharmacology

Prophylactic liraglutide treatment prevents amyloid plaque deposition, chronic inflammation and memory impairment in APP/PS1 mice

(2015) Paula L. McClean et al.   BEHAVIOURAL BRAIN RESEARCH

Novel GLP-1 (Glucagon-Like Peptide-1) Analogues and Insulin in the Treatment for Alzheimer’s Disease and Other Neurodegenerative Diseases

(2015) Valeria Calsolaro et al.   CNS DRUGS

Involvement of the CA1 GABAA receptors in MK-801-induced anxiolytic-like effects

(2014) Mohammad-Hasan Naseri et al.   BEHAVIOURAL PHARMACOLOGY

Chronic Treatment with the GLP1 Analogue Liraglutide Increases Cell Proliferation and Differentiation into Neurons in an AD Mouse Model

(2013) Vadivel Parthsarathy et al.   PLoS One

Energy Intake and Exercise as Determinants of Brain Health and Vulnerability to Injury and Disease

(2012) Mark P. Mattson   Cell Metabolism

Liraglutide improves hippocampal synaptic plasticity associated with increased expression of Mash1 in ob/ob mice

(2012) W D Porter et al.   INTERNATIONAL JOURNAL OF OBESITY

Neuroprotective actions of Glucagon-like peptide-1 in differentiated human neuroprogenitor cells

(2012) Kalpana Velmurugan et al.   JOURNAL OF NEUROCHEMISTRY

Novel GLP-1 mimetics developed to treat type 2 diabetes promote progenitor cell proliferation in the brain

(2011) A. Hamilton et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Acute low dose of MK-801 prevents memory deficits without altering hippocampal DARPP-32 expression and BDNF levels in sepsis survivor rats

(2010) Omar J. Cassol-Jr et al.   JOURNAL OF NEUROIMMUNOLOGY

Synaptic versus extrasynaptic NMDA receptor signalling: implications for neurodegenerative disorders

(2010) Giles E. Hardingham et al.   NATURE REVIEWS NEUROSCIENCE

Impairment of synaptic plasticity and memory formation in GLP-1 receptor KO mice: Interaction between type 2 diabetes and Alzheimer's disease

(2009) Talib Abbas et al.   BEHAVIOURAL BRAIN RESEARCH