Emerging Penetrating Neural Electrodes: In Pursuit of Large Scale and Longevity

Large-scale neural recordings with single neuron resolution using Neuropixels probes in human cortex

(2022) Angelique C. Paulk et al.   NATURE NEUROSCIENCE

Large-scale neural recordings call for new insights to link brain and behavior

(2022) Anne E. Urai et al.   NATURE NEUROSCIENCE

Human brain mapping with multithousand-channel PtNRGrids resolves spatiotemporal dynamics

(2022) Youngbin Tchoe et al.   Science Translational Medicine

Scalable Thousand Channel Penetrating Microneedle Arrays on Flex for Multimodal and Large Area Coverage BrainMachine Interfaces

(2022) Sang Heon Lee et al.   ADVANCED FUNCTIONAL MATERIALS

Single-neuron projectome of mouse prefrontal cortex

(2022) Le Gao et al.   NATURE NEUROSCIENCE

Prevention of the foreign body response to implantable medical devices by inflammasome inhibition

(2022) Damiano G. Barone et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Topological supramolecular network enabled high-conductivity, stretchable organic bioelectronics

(2022) Yuanwen Jiang et al.   SCIENCE

Brain-wide mapping reveals that engrams for a single memory are distributed across multiple brain regions

(2022) Dheeraj S. Roy et al.   Nature Communications

Multiplexed Monitoring of Neurochemicals via Electrografting-Enabled Site-Selective Functionalization of Aptamers on Field-Effect Transistors

(2022) Zan Gao et al.   ANALYTICAL CHEMISTRY

High-density single-unit human cortical recordings using the Neuropixels probe

(2022) Jason E. Chung et al.   NEURON

The advantages of mapping slow brain potentials using DC‐coupled graphene micro‐transistors: Clinical and translational applications

(2022) Rob. C Wykes et al.   Clinical and Translational Medicine

Ultraflexible electrode arrays for months-long high-density electrophysiological mapping of thousands of neurons in rodents

(2022) Zhengtuo Zhao et al.   Nature Biomedical Engineering

Survey of spiking in the mouse visual system reveals functional hierarchy

(2021) Joshua H. Siegle et al.   NATURE

Graphene active sensor arrays for long-term and wireless mapping of wide frequency band epicortical brain activity

(2021) R. Garcia-Cortadella et al.   Nature Communications

High-density neural recordings from feline sacral dorsal root ganglia with thin-film array

(2021) Zachariah J. Sperry et al.   Journal of Neural Engineering

High-density mapping of primate digit representations with a 1152-channel µECoG array

(2021) Taro Kaiju et al.   Journal of Neural Engineering

High-precision coding in visual cortex

(2021) Carsen Stringer et al.   CELL

Neuropixels 2.0: A miniaturized high-density probe for stable, long-term brain recordings

(2021) Nicholas A. Steinmetz et al.   SCIENCE

Foreign Body Reaction to Implanted Biomaterials and Its Impact in Nerve Neuroprosthetics

(2021) Alejandro Carnicer-Lombarte et al.   Frontiers in Bioengineering and Biotechnology

Viscoelastic surface electrode arrays to interface with viscoelastic tissues

(2021) Christina M. Tringides et al.   Nature Nanotechnology

Adaptive and multifunctional hydrogel hybrid probes for long-term sensing and modulation of neural activity

(2021) Seongjun Park et al.   Nature Communications

A Lubricated Nonimmunogenic Neural Probe for Acute Insertion Trauma Minimization and Long‐Term Signal Recording

(2021) Yeontaek Lee et al.   Advanced Science

Free‐Standing Nanofilm Electrode Arrays for Long‐Term Stable Neural Interfacings

(2021) Lei Gao et al.   ADVANCED MATERIALS

Anti-fouling peptide functionalization of ultraflexible neural probes for long-term neural activity recordings in the brain

(2021) Yimin Zou et al.   BIOSENSORS & BIOELECTRONICS

Novel transducers for high-channel-count neuroelectronic recording interfaces

(2021) Anton Guimerà-Brunet et al.   CURRENT OPINION IN BIOTECHNOLOGY

A Miniaturized 256-Channel Neural Recording Interface With Area-Efficient Hybrid Integration of Flexible Probes and CMOS Integrated Circuits

(2021) Sung-Yun Park et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Longevity and reliability of chronic unit recordings using the Utah, intracortical multi-electrode arrays

(2021) Caleb Sponheim et al.   Journal of Neural Engineering

Carbon-Based Fiber Materials as Implantable Depth Neural Electrodes

(2021) Xuefeng Fu et al.   Frontiers in Neuroscience

Explant Analysis of Utah Electrode Arrays Implanted in Human Cortex for Brain-Computer-Interfaces

(2021) Kevin Woeppel et al.   Frontiers in Bioengineering and Biotechnology

Multiplexed neural sensor array of graphene solution-gated field-effect transistors

(2020) Nathan Schaefer et al.   2D Materials

Neuroadhesive protein coating improves the chronic performance of neuroelectronics in mouse brain

(2020) Asiyeh Golabchi et al.   BIOSENSORS & BIOELECTRONICS

Switchless Multiplexing of Graphene Active Sensor Arrays for Brain Mapping

(2020) Ramon Garcia-Cortadella et al.   NANO LETTERS

Morphing electronics enable neuromodulation in growing tissue

(2020) Yuxin Liu et al.   NATURE BIOTECHNOLOGY

Massively parallel microwire arrays integrated with CMOS chips for neural recording

(2020) Abdulmalik Obaid et al.   Science Advances

BRICseq Bridges Brain-wide Interregional Connectivity to Neural Activity and Gene Expression in Single Animals

(2020) Longwen Huang et al.   CELL

Mechanically Robust, Softening Shape Memory Polymer Probes for Intracortical Recording

(2020) Allison Stiller et al.   Micromachines

CHIME: CMOS-Hosted in vivo Microelectrodes for Massively Scalable Neuronal Recordings

(2020) Mihaly Kollo et al.   Frontiers in Neuroscience

Ultraflexible Neural Electrodes for Long-Lasting Intracortical Recording

(2020) Fei He et al.   iScience

Cellular-scale silicon probes for high-density, precisely-localized neurophysiology

(2020) Daniel GD Egert et al.   JOURNAL OF NEUROPHYSIOLOGY

An approach for long-term, multi-probe Neuropixels recordings in unrestrained rats

(2020) Thomas Zhihao Luo et al.   eLife

Classifying Intracortical Brain-Machine Interface Signal Disruptions Based on System Performance and Applicable Compensatory Strategies: A Review

(2020) Collin F. Dunlap et al.   Frontiers in Neurorobotics

Shape perception via a high-channel-count neuroprosthesis in monkey visual cortex

(2020) Xing Chen et al.   SCIENCE

Locomotion-dependent remapping of distributed cortical networks

(2019) Kelly B. Clancy et al.   NATURE NEUROSCIENCE

Bioinspired neuron-like electronics

(2019) Xiao Yang et al.   NATURE MATERIALS

Parallel, minimally-invasive implantation of ultra-flexible neural electrode arrays

(2019) Zhengtuo Zhao et al.   Journal of Neural Engineering

Spontaneous behaviors drive multidimensional, brainwide activity

(2019) Carsen Stringer et al.   SCIENCE

High-dimensional geometry of population responses in visual cortex

(2019) Carsen Stringer et al.   NATURE

A whole-brain map of long-range inputs to GABAergic interneurons in the mouse medial prefrontal cortex

(2019) Qingtao Sun et al.   NATURE NEUROSCIENCE

Reconstruction of 1,000 Projection Neurons Reveals New Cell Types and Organization of Long-Range Connectivity in the Mouse Brain

(2019) Johan Winnubst et al.   CELL

Task-Dependent Changes in the Large-Scale Dynamics and Necessity of Cortical Regions

(2019) Lucas Pinto et al.   NEURON

Can One Concurrently Record Electrical Spikes from Every Neuron in a Mammalian Brain?

(2019) David Kleinfeld et al.   NEURON

Chronically implanted Neuropixels probes enable high-yield recordings in freely moving mice

(2019) Ashley L Juavinett et al.   eLife

High-Throughput Mapping of Long-Range Neuronal Projection Using In Situ Sequencing

(2019) Xiaoyin Chen et al.   CELL

An Integrated Brain-Machine Interface Platform With Thousands of Channels

(2019) Elon Musk et al.   JOURNAL OF MEDICAL INTERNET RESEARCH

Hierarchical organization of cortical and thalamic connectivity

(2019) Julie A. Harris et al.   NATURE

Distributed coding of choice, action and engagement across the mouse brain

(2019) Nicholas A. Steinmetz et al.   NATURE

A Compact Quad-Shank CMOS Neural Probe With 5,120 Addressable Recording Sites and 384 Fully Differential Parallel Channels

(2019) Shiwei Wang et al.   IEEE Transactions on Biomedical Circuits and Systems

Fundamental Limits to the Electrochemical Impedance Stability of Dielectric Elastomers in Bioelectronics

(2019) Paul Le Floch et al.   NANO LETTERS

A method for single-neuron chronic recording from the retina in awake mice

(2018) Guosong Hong et al.   SCIENCE

Topical Dexamethasone Administration Impairs Protein Synthesis and Neuronal Regeneration in the Olfactory Epithelium

(2018) Umberto Crisafulli et al.   Frontiers in Molecular Neuroscience

Nanofabricated Ultraflexible Electrode Arrays for High-Density Intracortical Recording

(2018) Xiaoling Wei et al.   Advanced Science

The logic of single-cell projections from visual cortex

(2018) Yunyun Han et al.   NATURE

High-Density, Long-Lasting, and Multi-region Electrophysiological Recordings Using Polymer Electrode Arrays

(2018) Jason E. Chung et al.   NEURON

SiNAPS: An implantable active pixel sensor CMOS-probe for simultaneous large-scale neural recordings

(2018) Gian Nicola Angotzi et al.   BIOSENSORS & BIOELECTRONICS

A Neural Probe With Up to 966 Electrodes and Up to 384 Configurable Channels in 0.13 $\mu$m SOI CMOS

(2017) Carolina Mora Lopez et al.   IEEE Transactions on Biomedical Circuits and Systems

Fully integrated silicon probes for high-density recording of neural activity

(2017) James J. Jun et al.   NATURE

Time Multiplexed Active Neural Probe with 1356 Parallel Recording Sites

(2017) Bogdan C. Raducanu et al.   SENSORS

Foreign Body Response to Intracortical Microelectrodes Is Not Altered with Dip-Coating of Polyethylene Glycol (PEG)

(2017) Heui C. Lee et al.   Frontiers in Neuroscience

Ultraflexible nanoelectronic probes form reliable, glial scar–free neural integration

(2017) Lan Luan et al.   Science Advances

Close-Packed Silicon Microelectrodes for Scalable Spatially Oversampled Neural Recording

(2016) Jorg Scholvin et al.   IEEE TRANSACTIONS ON BIOMEDICAL ENGINEERING

Chronicin vivostability assessment of carbon fiber microelectrode arrays

(2016) Paras R Patel et al.   Journal of Neural Engineering

Scanning electron microscopy of chronically implanted intracortical microelectrode arrays in non-human primates

(2016) James C Barrese et al.   Journal of Neural Engineering

Nanofabricated Neural Probes for Dense 3-D Recordings of Brain Activity

(2016) Gustavo Rios et al.   NANO LETTERS

Stable long-term chronic brain mapping at the single-neuron level

(2016) Tian-Ming Fu et al.   NATURE METHODS

Organization of long-range inputs and outputs of frontal cortex for top-down control

(2016) Siyu Zhang et al.   NATURE NEUROSCIENCE

Neural Stimulation and Recording with Bidirectional, Soft Carbon Nanotube Fiber Microelectrodes

(2015) Flavia Vitale et al.   ACS Nano

Mechanical failure modes of chronically implanted planar silicon-based neural probes for laminar recording

(2015) Takashi D.Y. Kozai et al.   BIOMATERIALS

Brain activity mapping at multiple scales with silicon microprobes containing 1,024 electrodes

(2015) Justin L. Shobe et al.   JOURNAL OF NEUROPHYSIOLOGY

Three-dimensional macroporous nanoelectronic networks as minimally invasive brain probes

(2015) Chong Xie et al.   NATURE MATERIALS

Tools for Probing Local Circuits: High-Density Silicon Probes Combined with Optogenetics

(2015) György Buzsáki et al.   NEURON

Progress towards biocompatible intracortical microelectrodes for neural interfacing applications

(2014) Mehdi Jorfi et al.   Journal of Neural Engineering

A mesoscale connectome of the mouse brain

(2014) Seung Wook Oh et al.   NATURE

Relationship between intracortical electrode design and chronic recording function

(2013) Lohitash Karumbaiah et al.   BIOMATERIALS

Intra-day signal instabilities affect decoding performance in an intracortical neural interface system

(2013) János A Perge et al.   Journal of Neural Engineering

A carbon-fiber electrode array for long-term neural recording

(2013) Grigori Guitchounts et al.   Journal of Neural Engineering

Failure mode analysis of silicon-based intracortical microelectrode arrays in non-human primates

(2013) James C Barrese et al.   Journal of Neural Engineering

Large-scale, high-density (up to 512 channels) recording of local circuits in behaving animals

(2013) Antal Berényi et al.   JOURNAL OF NEUROPHYSIOLOGY

Comprehensive characterization and failure modes of tungsten microwire arrays in chronic neural implants

(2012) Abhishek Prasad et al.   Journal of Neural Engineering

Ultrasmall implantable composite microelectrodes with bioactive surfaces for chronic neural interfaces

(2012) Takashi D. Yoshida Kozai et al.   NATURE MATERIALS

Bioinspired self-repairing slippery surfaces with pressure-stable omniphobicity

(2011) Tak-Sing Wong et al.   NATURE

How advances in neural recording affect data analysis

(2011) Ian H Stevenson et al.   NATURE NEUROSCIENCE

Single-Unit Stability Using Chronically Implanted Multielectrode Arrays

(2009) Adam S. Dickey et al.   JOURNAL OF NEUROPHYSIOLOGY

Correlations of Neuronal and Microvascular Densities in Murine Cortex Revealed by Direct Counting and Colocalization of Nuclei and Vessels

(2009) P. S. Tsai et al.   JOURNAL OF NEUROSCIENCE

Advanced Neurotechnologies for Chronic Neural Interfaces: New Horizons and Clinical Opportunities

(2008) D. R. Kipke et al.   JOURNAL OF NEUROSCIENCE