Efficacy and safety of adjunctive padsevonil in adults with drug‐resistant focal epilepsy: Results from two double‐blind, randomized, placebo‐controlled trials
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Title
Efficacy and safety of adjunctive padsevonil in adults with drug‐resistant focal epilepsy: Results from two double‐blind, randomized, placebo‐controlled trials
Authors
Keywords
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Journal
Epilepsia Open
Volume 7, Issue 4, Pages 758-770
Publisher
Wiley
Online
2022-09-30
DOI
10.1002/epi4.12656
References
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Note: Only part of the references are listed.- Functional characterization of the antiepileptic drug candidate, padsevonil, on GABA A receptors
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- Pharmacological Profile of the Novel Antiepileptic Drug Candidate Padsevonil: Interactions with Synaptic Vesicle 2 Proteins and the GABAA Receptor
- (2019) Martyn Wood et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Safety and efficacy of adjunctive cenobamate (YKP3089) in patients with uncontrolled focal seizures: a multicentre, double-blind, randomised, placebo-controlled, dose-response trial
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- The Benzodiazepine Binding Sites of GABA A Receptors
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- Treatment Outcomes in Patients With Newly Diagnosed Epilepsy Treated With Established and New Antiepileptic Drugs
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- The Burden of Severely Drug-Refractory Epilepsy: A Comparative Longitudinal Evaluation of Mortality, Morbidity, Resource Use, and Cost Using German Health Insurance Data
- (2017) Adam Strzelczyk et al. Frontiers in Neurology
- What can we do for people with drug-resistant epilepsy?
- (2016) Jerome Engel NEUROLOGY
- Clobazam: A Safe, Efficacious, and Newly Rediscovered Therapeutic for Epilepsy
- (2015) Angela C. Gauthier et al. CNS Neuroscience & Therapeutics
- The consequences of refractory epilepsy and its treatment
- (2014) Kenneth D. Laxer et al. EPILEPSY & BEHAVIOR
- Clobazam and Its Active Metabolite N-desmethylclobazam Display Significantly Greater Affinities for α2- versus α1-GABAA–Receptor Complexes
- (2014) Henrik Sindal Jensen et al. PLoS One
- Pharmacoresistant epilepsy: Unmet needs in solving the puzzle(s)
- (2013) Donald F. Weaver et al. EPILEPSIA
- Adjunctive perampanel for refractory partial-onset seizures: Randomized phase III study 304
- (2012) J. A. French et al. NEUROLOGY
- Patterns of treatment response in newly diagnosed epilepsy
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- Examining the Clinical Utility of Lacosamide
- (2010) Steve Chung et al. CNS DRUGS
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