Neurotrophins and B-cell malignancies

Emerging new anticancer biological therapies in 2013 (haematological malignancies)

(2014) Laurent Plawny et al.   CURRENT OPINION IN ONCOLOGY

Role of Endogenous Brain-Derived Neurotrophic Factor and Sortilin in B Cell Survival

(2014) A.-L. Fauchais et al.   JOURNAL OF IMMUNOLOGY

Idelalisib and Rituximab in Relapsed Chronic Lymphocytic Leukemia

(2014) Richard R. Furman et al.   NEW ENGLAND JOURNAL OF MEDICINE

Chimeric Antigen Receptor Therapy for Cancer

(2013) David M. Barrett et al.   Annual Review of Medicine

Rituximab causes a polarization of B cells that augments its therapeutic function in NK-cell-mediated antibody-dependent cellular cytotoxicity

(2013) D. Rudnicka et al.   BLOOD

ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing platelets

(2013) Andrew J Souers et al.   NATURE MEDICINE

Pathogenesis of Human B Cell Lymphomas

(2012) Arthur L. Shaffer et al.   Annual Review of Immunology

Targeting the microenvironment in chronic lymphocytic leukemia is changing the therapeutic landscape

(2012) Jan A. Burger   CURRENT OPINION IN ONCOLOGY

Nerve growth factor receptor (NGFR): a potential marker for specific molecular subtypes of breast cancer

(2012) Julia Y S Tsang et al.   JOURNAL OF CLINICAL PATHOLOGY

Differential Expression of Neurotensin and Specific Receptors, NTSR1 and NTSR2, in Normal and Malignant Human B Lymphocytes

(2012) S. Saada et al.   JOURNAL OF IMMUNOLOGY

The Bruton tyrosine kinase inhibitor PCI-32765 thwarts chronic lymphocytic leukemia cell survival and tissue homing in vitro and in vivo

(2011) S. Ponader et al.   BLOOD

Pro-nerve Growth Factor Induces Autocrine Stimulation of Breast Cancer Cell Invasion through Tropomyosin-related Kinase A (TrkA) and Sortilin Protein

(2011) Yohann Demont et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Endogenous Neurotrophins and Trk Signaling in Diffuse Large B Cell Lymphoma Cell Lines Are Involved in Sensitivity to Rituximab-Induced Apoptosis

(2011) Cynthia Bellanger et al.   PLoS One

TrkB is highly expressed in NSCLC and mediates BDNF-induced the activation of Pyk2 signaling and the invasion of A549 cells

(2010) Siyang Zhang et al.   BMC CANCER

Augmentation of regulatory B cell activity in experimental allergic encephalomyelitis by glatiramer acetate

(2010) Sakhina Begum-Haque et al.   JOURNAL OF NEUROIMMUNOLOGY

Neurotrophin receptors TrkA and TrkC cause neuronal death whereas TrkB does not

(2010) Vassiliki Nikoletopoulou et al.   NATURE

Neurotrophin signaling through tropomyosin receptor kinases contributes to survival and proliferation of non-Hodgkin lymphoma

(2009) Lynn F. Sniderhan et al.   EXPERIMENTAL HEMATOLOGY

Nerve Growth Factor and Neurotrophin-3 Mediate Survival of Pulmonary Plasma Cells during the Allergic Airway Inflammation

(2009) M. Abram et al.   JOURNAL OF IMMUNOLOGY

Activation of the p75 Neurotrophin Receptor through Conformational Rearrangement of Disulphide-Linked Receptor Dimers

(2009) Marçal Vilar et al.   NEURON

TrkA overexpression enhances growth and metastasis of breast cancer cells

(2009) C Lagadec et al.   ONCOGENE

B lymphocytes: how they develop and function

(2008) T. W. LeBien et al.   BLOOD

Plasma cell differentiation and survival

(2008) David Tarlinton et al.   CURRENT OPINION IN IMMUNOLOGY

Proneurotrophins Require Endocytosis and Intracellular Proteolysis to Induce TrkA Activation

(2008) Jacqueline Boutilier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neurotrophins and Their Receptors Stimulate Melanoma Cell Proliferation and Migration

(2008) Francesca Truzzi et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

ProNGF inhibits NGF-mediated TrkA activation in PC12 cells

(2008) Bettina Sobottka et al.   JOURNAL OF NEUROCHEMISTRY