Article
Biochemistry & Molecular Biology
Tohru Ogihara, Makoto Mino
Summary: When evaluating the nutritional status of preterm infants, it is important to compare the data with healthy term infants and consider the gestational age rather than birth weight. There is limited data on the correlation between gestational age and vitamin E concentrations in preterm infants, and the oxidizability of polyunsaturated fatty acids is lower in preterm infants. Clinical trials of vitamin E supplementation in preterm infants have mostly been unsuccessful, and there is a need for further research in modern neonatal medicine.
FREE RADICAL BIOLOGY AND MEDICINE
(2022)
Article
Obstetrics & Gynecology
Jenny Wu, Anna E. Denoble, Jeffrey A. Kuller, Sarah K. Dotters-Katz
Summary: Studies comparing retention versus removal of cervical cerclage in women with PPROM showed potential prolongation of latency to delivery with retention, but also potential increase in maternal infectious morbidity. Limited evidence found no significant differences in neonatal outcomes, with most studies limited by retrospective nature and small sample sizes.
OBSTETRICAL & GYNECOLOGICAL SURVEY
(2021)
Article
Pediatrics
Grace Y. Lai, Sanaa Abdelmageed, Raye-Ann O. DeRegnier, Deborah Gaebler-Spira, Maria L. V. Dizon, Sandi K. Lam
Summary: Research suggests that greater ventriculomegaly in preterm infants with intraventricular hemorrhage is associated with worse functional outcomes at school age. Analysis shows that maximum FOHR and FOHR at Neurosurgery consult and last follow-up scan can predict poorer functional outcomes.
PEDIATRIC RESEARCH
(2022)
Review
Obstetrics & Gynecology
Csaba Siffel, Kristin D. Kistler, Sujata P. Sarda
Summary: The study found that intraventricular hemorrhage is a common complication of extremely preterm birth, with varying incidence rates by region, and the global incidence of intraventricular hemorrhage grade 2 is not well documented.
JOURNAL OF PERINATAL MEDICINE
(2021)
Article
Pediatrics
Kimberly N. Grelli, Roberta L. Keller, Elizabeth E. Rogers, J. Colin Partridge, Duan Xu, A. James Barkovich, Dawn Gano
Summary: Cumulative supplemental oxygen and mean airway pressure are associated with bronchopulmonary dysplasia (BPD) and white matter injury (WMI) in preterm infants, and early respiratory status influences adverse neurodevelopmental outcomes.
PEDIATRIC RESEARCH
(2021)
Article
Medicine, General & Internal
Agnes Grill, Monika Olischar, Michael Weber, Lukas Unterasinger, Angelika Berger, Harald Leitich
Summary: In preterm infants, clinical sepsis is more common than culture-proven sepsis and is equally valuable in predicting mortality and mortality or severe morbidity.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Yuriko Iwahata, Junichi Hasegawa, Chika Homma, Hideyuki Iwahata, Natsumi Furuya, Haruhiro Kondo, Nao Suzuki
Summary: This retrospective case-control study evaluated the impact of perinatal factors closely related to the development of neonatal intraventricular hemorrhage (IVH) in preterm infants. The results showed that clinical chorioamnionitis was strongly associated with IVH in premature infants born before 30 weeks of gestation, while exposure to magnesium sulfate suggested a neuroprotective effect against IVH.
CLINICAL AND EXPERIMENTAL OBSTETRICS & GYNECOLOGY
(2022)
Article
Clinical Neurology
Chunxiang Zhang, Xin Zhao, Meiying Cheng, Kaiyu Wang, Xiaoan Zhang
Summary: Synthetic MRI can provide comprehensive information on brain parameters, which is crucial for diagnosing and evaluating the impact of intraventricular hemorrhage in premature infants. The T1 and T2 relaxation times, PD values, and brain volume changes demonstrated by synthetic MRI contribute to the diagnosis and assessment of IVH.
FRONTIERS IN NEUROLOGY
(2021)
Article
Obstetrics & Gynecology
Martha B. Kole-White, Linda A. Nelson, Megan Lord, Phinnara Has, Erika F. Werner, Dwight J. Rouse, Erica J. Hardy
Summary: This study compared the impact of oral-only antibiotics treatment with intravenous antibiotics followed by oral antibiotics treatment on pregnancy latency in patients with preterm premature rupture of membranes. The results suggested that there was no significant difference in pregnancy latency between the oral-only antibiotics regimen and the standard regimen.
AMERICAN JOURNAL OF OBSTETRICS & GYNECOLOGY MFM
(2021)
Article
Clinical Neurology
Luis Eduardo de Figueiredo Vinagre, Jamil Pedro de Siqueira Caldas, Sergio Tadeu Martins Marba, Renato Soibelmann Procianoy, Rita de Cassia Silveira, Maria Albertina Santiago Rego, Daniela Marques de Lima Mota Ferreira, Jose Mariano Sales Alves Junior, Juliana Paula Ferraz dos Santo, Carolina Boschi Gimenes, Nathalia Moura de Mello e Silva, Maria Rafaela Conde Gonzalez, Regina Paula Guimaraes Vieira Cavalcante da Silva, Dafne Barcala Coutinho do Amaral Gomez, Marynea Silva do Vale, Ligia Maria Suppo de Souza Rugolo, Joice Fabiola Meneguel Ogata, Edna Maria de Albuquerque Diniz, Jorge Hecker Luz, Joao Henrique Carvalho Leme de Almeida, Marcia Pereira Alves de Souza, Walusa Assad Goncalves Ferri
Summary: This study investigated the incidence and trend of intraventricular hemorrhage (IVH) in very low birth weight preterm infants in 18 centers in Brazil. The results showed an increasing trend in the incidence of IVH over time, with a high rate of severe IVH. There were also differences in the incidence among the different centers.
EUROPEAN JOURNAL OF PAEDIATRIC NEUROLOGY
(2022)
Review
Multidisciplinary Sciences
Emma Persad, Greta Sibrecht, Martin Ringsten, Simon Karlelid, Olga Romantsik, Tommy Ulinder, Israel Junior Borges do Nascimento, Maria Bjorklund, Anneliese Arno, Matteo Bruschettini
Summary: Increasing placental transfusion at birth may reduce mortality in very preterm infants, while there is extremely limited evidence on the effects of other interventions to reduce blood loss after birth. Further studies are needed to assess the effectiveness of different blood-saving approaches following placental transfusion.
Article
Medicine, General & Internal
Marion Rouzaire, Marion Corvaisier, Virginie Roumeau, Aurelien Mulliez, Feras Sendy, Amelie Delabaere, Denis Gallot
Summary: Factors predictive of short latency exceeding 48 h after PPROM include the need for tocolysis, a cervical length less than 25 mm at admission, and the existence of anamnios. Outpatient follow-up did not result in increased maternal morbidity or neonatal mortality.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Obstetrics & Gynecology
Michal Fishel Bartal, Lynda G. Ugwu, William A. Grobman, Jennifer L. Bailit, Uma M. Reddy, Ronald J. Wapner, Michael W. Varner, John M. Thorp, Steve N. Caritis, Mona Prasad, Alan T. N. Tita, George R. Saade, Dwight J. Rouse
Summary: The rate of preterm premature rupture of membranes (PROM) and the likelihood of composite maternal or neonatal morbidity after preterm PROM were similar for twin and singleton gestations in a large, diverse cohort.
OBSTETRICS AND GYNECOLOGY
(2021)
Article
Microbiology
Maria Paola Bonasoni, Andrea Palicelli, Giulia Dalla Dea, Giuseppina Comitini, Paola Nardini, Loredana Vizzini, Giuseppe Russello, Marcellino Bardaro, Edoardo Carretto
Summary: Klebsiella pneumoniae infection leading to acute chorioamnionitis caused intrauterine fetal demise in a case presented here. The mother was admitted at 18 weeks + 1 day for threatened abortion, with IUFD occurring 11 days later. The correct treatment was initiated based on fetal microbiological results, leading to full patient recovery.
Article
Medical Laboratory Technology
Giorgia Gasparroni, Alessandro Graziosi, Iliana Bersani, Massimo Caulo, Bashir Moataza, Hanna Aboulgar, Hala Mufeed, Iman Iskander, Maria Kornacka, Darek Gruzfeld, Andrea Dotta, Immacolata Savarese, Natalia Chukhlantseva, Lucia Gabriella Tina, Francesco Nigro, Giovanni Livolti, Fabio Galvano, Caterina Di Battista, Ebe D'Adamo, Adele Patrizia Primavera, Giuseppe Lapergola, Mariangela Conte, Rita Salomone, Marika Perrotta, Daniele Panichi, Gabriella Levantini, Milena Catenaro, Chiara Strozzi, Antonio Maconi, Giacomo Centini, Francesco Chiarelli, Francesco D'Antonio, Danilo A. W. Gavilanes, Diego Gazzolo
Summary: The study validated the role of S100B protein in the early diagnosis and prognosis of IVH in preterm infants, especially emphasizing its importance when standard monitoring procedures are not available. Elevated levels of S100B correlated with the severity of intraventricular hemorrhage and the location and extent of neurological lesions.
CLINICAL CHEMISTRY AND LABORATORY MEDICINE
(2021)
Article
Neurosciences
Adam Vacek, Grant Mair, Philip White, Philip M. Bath, Keith W. Muir, Rustam Al-Shahi Salman, Chloe Martin, David Dye, Francesca M. Chappell, Ruediger von Kummer, Malcolm Macleod, Nikola Sprigg, Joanna M. Wardlaw
Summary: This study evaluated the performance of e-ASPECTS software in delineating the extent of intracranial hemorrhage (ICH) on brain CT scans. The results showed that the software achieved excellent or good delineation of ICH extent in 71% of cases. However, it was more likely to over- or under-estimate the extent when ICH was more extensive, intraventricular, or extra-axial.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Mathias Jacobsen Bach, Audrone Jakubauskaite, Ian Law, Otto Molby Henriksen, Inger Havsteen, Alexander Cuculiza Henriksen, Sverre Rosenbaum, Lisbeth Marner
Summary: This study found that the rCBFacz value after ACZ challenge can serve as an important indicator for predicting future cerebrovascular events, with high accuracy and prognostic value.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Tak Kyu Oh, Saeyeon Kim, In-Ae Song
Summary: The study found that many survivors of nontraumatic intracranial hemorrhage in South Korea experience unemployment, decreased household income, and newly acquired disability after intensive care unit admission. However, these changes are not associated with 2-year all-cause mortality.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Eduardo Sousa de Melo, Rodrigo de Paiva Bezerra, Arthur Cesario de Holanda, Maria Junia Lira e Silva, Paloma Peter Travassos, Tayne Fernanda Lemos da Silva, Genova Maria de Azevedo Oliveira, Silvia Marinho Martins Alves, Carolina de Araujo Medeiros, Maria das Neves Dantas da Silveira Barros, Wilson Alves de Oliveira, Gisele Sampaio Silva, Luciana Patrizia Alves de Andrade Valenca
Summary: Cardiac involvement has been found to be the predominant factor correlated with stroke in Chagas disease. While atherosclerosis-related risk factors are prevalent, their influence on ischemic stroke in Chagas disease appears limited.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Pingping Zheng, Ning Zhang, Zixi Chen
Summary: This case presents a rare infectious cause of stroke and air embolism involving a pulmonary abscess and pulmonary vein thrombosis. Early detection, diagnosis, and appropriate treatment of infected systemic embolism in young patients are crucial to prevent serious complications.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Filippo Luca Gurgoglione, Luigi Vignali, Maria Alberta Cattabiani, Emilia Solinas, Giorgio Benatti, Iacopo Tadonio, Federico Barocelli, Chiara Dizdari, Domenico Tuttolomondo, Diego Ardissino, Francesco Nicolini, Giampaolo Niccoli
Summary: The incidence of recurrent ischemic neurological events after transcatheter patent foramen ovale closure is relatively low. Obesity, Risk of Paradoxical Embolism score < 7, and migraine are independent positive predictors of recurrent stroke or transient ischemic attack.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Angelo Cascio Rizzo, Ghil Schwarz, Amedeo Cervo, Giuditta Giussani, Chiara Ceresa, Antonella Gatti, Fausto De Angeli, Cristina Motto, Angelo Guccione, Rachele Tortorella, Giuseppe Granata, Claudia Rollo, Antonio Macera, Mariangela Piano, Guglielmo Pero, Elio Clemente Agostoni
Summary: This study aimed to evaluate the efficacy and safety of endovascular treatment (EVT) in primary and EVT-induced secondary medium-vessel occlusions (MeVO). The results showed that primary MeVO had poorer outcomes in terms of complications, EVT efficacy, and the proportion of patients with a modified Rankin Scale (mRS) of 0-2 at 3 months compared to exclusive large-vessel occlusion (LVO). However, EVT-induced secondary MeVO showed similar safety and efficacy outcomes as exclusive LVO and had better outcomes in terms of mRS 0-2 compared to primary MeVO.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jing Zhang, Chenming Wei, Jian Wu
Summary: This case report describes a patient with Bloom syndrome who developed acute cerebral infarction along with elevated antiphospholipid antibodies, suggesting a possible association between immune and coagulation abnormalities caused by Bloom syndrome and the development of acute cerebral infarction.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Yunxia Zhou, Shenglan He, Yanhong Hu
Summary: Compared with clopidogrel, DAPT with ticagrelor plus aspirin was associated with significantly lower thromboembolic events without an increase in hemorrhagic events in the treatment of intracranial aneurysms, according to the one-year clinical outcome analysis. However, larger upcoming trials are needed to confirm the effectiveness and safety of ticagrelor-associated DAPT.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Edvania Andrade de Moura Silva, Ludmilla Ribeiro Batista, Marcela Aline Fernandes Braga, Luci Fuscaldi Teixeira-Salmela, Christina Danielli Coelho de Morais Faria, Iza Faria-Fortini
Summary: The study found that stroke severity is the best predictor of self-perceived manual ability at both three and six months after stroke. Age, although significant, contributes little to the prediction of manual ability.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Sidarrth Prasad, Erica M. Jones, Mehari Gebreyohanns, Veronica Aguilera, DaiWai M. Olson, Jane A. Anderson, Sean I. Savitz, Salvador C. Flores, Steven J. Warach, Charlotte E. Rhodes, Mark P. Goldberg, Nneka L. Ifejika
Summary: This study identified the barriers and facilitators to adopting tenecteplase (TNK) as a thrombolytic treatment for acute ischemic stroke (AIS) by conducting qualitative research with stroke clinicians in Texas. The findings suggest that providing evidence and identifying key change processes can help clinicians achieve consensus on adopting TNK for AIS treatment.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Jeshma Jayan, Sunil K. Narayan, Yasmin Nesha Haniffa, Navin Kumar
Summary: This study investigated the effects of transcranial electrical and magnetic stimulation on somatosensory evoked potentials in chronic ischemic stroke patients, finding that the real tDCS and rTMS combination results in significant improvement and is safe for use.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Phoebe M. Tran, Cenjing Zhu, William T. Harris II, Sajeesh K. Kamala Raghavan, Agricola Odoi, Liem Tran
Summary: This study assessed the geographic accessibility of stroke rehabilitation facilities in Tennessee. The study found that rural counties had significantly longer travel distances and times compared to urban counties. Counties with high and medium stroke prevalence also had higher travel times and distances compared to low stroke prevalence counties. Therefore, addressing transportation barriers and implementing tele-rehabilitation are crucial for improving access to stroke aftercare in these areas.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Lili Xu, Shuaiyu Chen, Jing Xu, Yanyan Shi, Zhihang Huang, Meng Wang, Ziqiao Wei, Hui Cao, Junshan Zhou, Wei Wang, Mingyang Du
Summary: This study found that the Chinese Visceral Adiposity Index (CVAI) is positively correlated with 90-day poor outcome in Chinese ischemic stroke patients after endovascular thrombectomy (EVT).
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)
Article
Neurosciences
Guangying Wu, Shuhua Li, Min Luo, Xiaotian Li, Xinghua Zhu, Junhuai Zhang, Qian He, Qian Yang, Guojiang Zhao, Shasha Luo, Zhijie Yang
Summary: The study aimed to investigate the relationship between serum alkaline phosphatase (ALP) levels and the severity and prognosis of intracerebral hemorrhage (ICH). The results showed that serum ALP levels in ICH patients were significantly elevated and correlated with hematoma volume and Glasgow coma scale (GCS) score. High serum ALP levels may serve as a potential predictor for the severity and unfavorable prognosis of ICH.
JOURNAL OF STROKE & CEREBROVASCULAR DISEASES
(2024)