Ligation of CD180 inhibits IFN-α signaling in a Lyn-PI3K-BTK-dependent manner in B cells

Autoreactive B Cells Discriminate CpG-Rich and CpG-Poor DNA and This Response Is Modulated by IFN- 

(2014) M. B. Uccellini et al.   JOURNAL OF IMMUNOLOGY

Activation-induced necroptosis contributes to B-cell lymphopenia in active systemic lupus erythematosus

(2014) H Fan et al.   Cell Death & Disease

Autoantibodies from long-lived ‘memory’ plasma cells of NZB/W mice drive immune complex nephritis

(2013) Qingyu Cheng et al.   ANNALS OF THE RHEUMATIC DISEASES

Targeting antigens to CD180 rapidly induces antigen-specific IgG, affinity maturation, and immunological memory

(2013) Jay W. Chaplin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Maintenance of Anti-Sm/RNP Autoantibody Production by Plasma Cells Residing in Ectopic Lymphoid Tissue and Bone Marrow Memory B Cells

(2013) J. S. Weinstein et al.   JOURNAL OF IMMUNOLOGY

Cell-surface expression of the TLR homolog CD180 in circulating cells from splenic and nodal marginal zone lymphomas

(2013) L Miguet et al.   LEUKEMIA

SLE Peripheral Blood B Cell, T Cell and Myeloid Cell Transcriptomes Display Unique Profiles and Each Subset Contributes to the Interferon Signature

(2013) Amy M. Becker et al.   PLoS One

Pathogenesis of lupus-like nephritis through autoimmune antibody produced by CD180-negative B lymphocytes in NZBWF1 mouse

(2012) Kazuko Fujita et al.   IMMUNOLOGY LETTERS

B Cell TLR7 Expression Drives Anti-RNA Autoantibody Production and Exacerbates Disease in Systemic Lupus Erythematosus-Prone Mice

(2012) S.-H. Hwang et al.   JOURNAL OF IMMUNOLOGY

Interferon-α induces unabated production of short-lived plasma cells in pre-autoimmune lupus-prone (NZB×NZW)F1 mice but not in BALB/c mice

(2011) Alexis Mathian et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Anti-CD180 (RP105) Activates B Cells To Rapidly Produce Polyclonal Ig via a T Cell and MyD88-Independent Pathway

(2011) Jay W. Chaplin et al.   JOURNAL OF IMMUNOLOGY

Serum soluble MD-1 levels increase with disease progression in autoimmune prone MRLlpr/lpr mice

(2011) Sumiyo Sasaki et al.   MOLECULAR IMMUNOLOGY

Inflammatory signaling compromises cell responses to interferon alpha

(2011) W-C HuangFu et al.   ONCOGENE

Mechanisms of B cell autoimmunity in SLE

(2011) Thomas Dörner et al.   ARTHRITIS RESEARCH & THERAPY

Potentiation of TLR9 responses for human naïve B-cell growth through RP105 signaling

(2010) Kazuko Yamazaki et al.   CLINICAL IMMUNOLOGY

Interferon-alpha: A Therapeutic Target in Systemic Lupus Erythematosus

(2010) Mary K. Crow   RHEUMATIC DISEASE CLINICS OF NORTH AMERICA

Neutralization of interferon-α/β-inducible genes and downstream effect in a phase I trial of an anti-interferon-α monoclonal antibody in systemic lupus erythematosus

(2009) Yihong Yao et al.   ARTHRITIS AND RHEUMATISM

Regulation of autoreactive B cell responses to endogenous TLR ligands

(2009) Ana Maria Avalos et al.   AUTOIMMUNITY

Murine B Cell Response to TLR7 Ligands Depends on an IFN-  Feedback Loop

(2009) N. M. Green et al.   JOURNAL OF IMMUNOLOGY

Tonic B cell activation by Radioprotective105/MD-1 promotes disease progression in MRL/lpr mice

(2008) T. Kobayashi et al.   INTERNATIONAL IMMUNOLOGY