Bioinspired sandwich-like hybrid surface functionalized scaffold capable of regulating osteogenesis, angiogenesis, and osteoclastogenesis for robust bone regeneration

Osteoblast/Osteoclast and Immune Cocktail Therapy of an Exosome/Drug Delivery Multifunctional Hydrogel Accelerates Fracture Repair

(2022) Bobin Mi et al.   ACS Nano

Scaffold-Free Spheroids with Two-Dimensional Heteronano-Layers (2DHNL) Enabling Stem Cell and Osteogenic Factor Codelivery for Bone Repair

(2022) Xifeng Liu et al.   ACS Nano

Gold nanorods modified by endogenous protein with light-irradiation enhance bone repair via multiple osteogenic signal pathways

(2022) Huajian Shan et al.   BIOMATERIALS

Polydopamine-mediated graphene oxide and nanohydroxyapatite-incorporated conductive scaffold with an immunomodulatory ability accelerates periodontal bone regeneration in diabetes

(2022) Yazhen Li et al.   Bioactive Materials

Sequential gastrodin release PU/n-HA composite scaffolds reprogram macrophages for improved osteogenesis and angiogenesis

(2022) Limei Li et al.   Bioactive Materials

Emodin Suppresses the Migration and Invasion of Melanoma Cells

(2021) Chi Liu et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

A low-temperature-printed hierarchical porous sponge-like scaffold that promotes cell-material interaction and modulates paracrine activity of MSCs for vascularized bone regeneration

(2021) Meifei Lian et al.   BIOMATERIALS

Mussel patterned with 4D biodegrading elastomer durably recruits regenerative macrophages to promote regeneration of craniofacial bone

(2021) Xuzheng Liu et al.   BIOMATERIALS

Multifunctional magnesium incorporated scaffolds by 3D-Printing for comprehensive postsurgical management of osteosarcoma

(2021) Jing Long et al.   BIOMATERIALS

Spatiotemporal blood vessel specification at the osteogenesis and angiogenesis interface of biomimetic nanofiber-enabled bone tissue engineering

(2021) Yuankun Zhai et al.   BIOMATERIALS

Immunopolarization-regulated 3D printed-electrospun fibrous scaffolds for bone regeneration

(2021) Xingzhi Liu et al.   BIOMATERIALS

Nanoclay mineral-reinforced macroporous nanocomposite scaffolds for in situ bone regeneration: In vitro and in vivo studies

(2021) Minhao Wu et al.   MATERIALS & DESIGN

Biofunctionalized composite scaffold to potentiate osteoconduction, angiogenesis, and favorable metabolic microenvironment for osteonecrosis therapy

(2021) Tongtong Zhu et al.   Bioactive Materials

Fabrication of Dexamethasone-Loaded Dual-Metal–Organic Frameworks on Polyetheretherketone Implants with Bacteriostasis and Angiogenesis Properties for Promoting Bone Regeneration

(2021) Tianhua Xiao et al.   ACS Applied Materials & Interfaces

Solvent Mediating the in Situ Self-Assembly of Polysaccharides for 3D Printing Biomimetic Tissue Scaffolds

(2021) Rongrong Zhang et al.   ACS Nano

An improved osseointegration of metal implants by pitavastatin loaded multilayer films with osteogenic and angiogenic properties

(2021) Weizhen Chen et al.   BIOMATERIALS

A micro/nano-biomimetic coating on titanium orchestrates osteo/angio-genesis and osteoimmunomodulation for advanced osseointegration

(2021) Long Bai et al.   BIOMATERIALS

Dual-functional polyetheretherketone surface modification for regulating immunity and bone metabolism

(2021) Shicheng Huo et al.   CHEMICAL ENGINEERING JOURNAL

3D bioprinting of proangiogenic constructs with induced immunomodulatory microenvironments through a dual cross-linking procedure using laponite incorporated bioink

(2021) Zhenjiang Ma et al.   COMPOSITES PART B-ENGINEERING

Ethoprophos induces cardiac toxicity in zebrafish embryos

(2021) Meifeng Li et al.   ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY

Mussel-inspired functionalization of electrospun scaffolds with polydopamine-assisted immobilization of mesenchymal stem cells-derived small extracellular vesicles for enhanced bone regeneration

(2021) Xin Xing et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Suppression of breast cancer-associated bone loss with osteoblast proteomes via Hsp90ab1/moesin-mediated inhibition of TGFβ/FN1/CD44 signaling

(2021) Xun Sun et al.   Theranostics

Advanced PLGA hybrid scaffold with a bioactive PDRN/BMP2 nanocomplex for angiogenesis and bone regeneration using human fetal MSCs

(2021) Da-Seul Kim et al.   Science Advances

Wnt7b Inhibits Osteoclastogenesis via AKT Activation and Glucose Metabolic Rewiring

(2021) Fanzi Wu et al.   Frontiers in Cell and Developmental Biology

A baicalin-loaded coaxial nanofiber scaffold regulated inflammation and osteoclast differentiation for vascularized bone regeneration

(2021) Shue Jin et al.   Bioactive Materials

Parathyroid Hormone Derivative with Reduced Osteoclastic Activity Promoted Bone Regeneration via Synergistic Bone Remodeling and Angiogenesis

(2020) Jinghuan Huang et al.   Small

Polyhedral Oligomeric Silsesquioxane-Incorporated Gelatin Hydrogel Promotes Angiogenesis during Vascularized Bone Regeneration

(2020) Mingjiao Chen et al.   ACS Applied Materials & Interfaces

3D printing of Haversian bone–mimicking scaffolds for multicellular delivery in bone regeneration

(2020) Meng Zhang et al.   Science Advances

Nanoscaled Bionic Periosteum Orchestrating the Osteogenic Microenvironment for Sequential Bone Regeneration

(2020) Hanwen Li et al.   ACS Applied Materials & Interfaces

ZIF-8-Modified Multifunctional Bone-Adhesive Hydrogels Promoting Angiogenesis and Osteogenesis for Bone Regeneration

(2020) Yanhua Liu et al.   ACS Applied Materials & Interfaces

Materials design for bone-tissue engineering

(2020) Gerry L. Koons et al.   Nature Reviews Materials

Inspired by Nature: Facile Design of Nanoclay–Organic Hydrogel Bone Sealant with Multifunctional Properties for Robust Bone Regeneration

(2020) Chung‐Sung Lee et al.   ADVANCED FUNCTIONAL MATERIALS

Biomimetic osteogenic peptide with mussel adhesion and osteoimmunomodulatory functions to ameliorate interfacial osseointegration under chronic inflammation

(2020) Jiaxiang Bai et al.   BIOMATERIALS

Sequential growth factor releasing double cryogel system for enhanced bone regeneration

(2020) Seunghun S. Lee et al.   BIOMATERIALS

Engineered three-dimensional scaffolds for enhanced bone regeneration in osteonecrosis

(2020) Tongtong Zhu et al.   Bioactive Materials

Photocrosslinkable nanocomposite ink for printing strong, biodegradable and bioactive bone graft

(2020) Yuhe Yang et al.   BIOMATERIALS

Bioinspired Functional Black Phosphorus Electrospun Fibers Achieving Recruitment and Biomineralization for Staged Bone Regeneration

(2020) Liang Cheng et al.   Small

Osteogenesis, angiogenesis and immune response of Mg-Al layered double hydroxide coating on pure Mg

(2020) Shi Cheng et al.   Bioactive Materials

Covalent grafting of hyperbranched poly-L-lysine on Ti-based implants achieves dual functions of antibacteria and promoted osteointegration in vivo

(2020) Zhijian Yang et al.   BIOMATERIALS

Hierarchically Patterned Polydopamine-Containing Membranes for Periodontal Tissue Engineering

(2019) Mohammad Mahdi Hasani-Sadrabadi et al.   ACS Nano

Versatile Polydopamine Platforms: Synthesis and Promising Applications for Surface Modification and Advanced Nanomedicine

(2019) Wei Cheng et al.   ACS Nano

Hierarchically Porous Hydroxyapatite Hybrid Scaffold Incorporated with Reduced Graphene Oxide for Rapid Bone Ingrowth and Repair

(2019) Kai Zhou et al.   ACS Nano

Triple PLGA/PCL Scaffold Modification Including Silver Impregnation, Collagen Coating, and Electrospinning Significantly Improve Biocompatibility, Antimicrobial, and Osteogenic Properties for Orofacial Tissue Regeneration

(2019) Yunzhu Qian et al.   ACS Applied Materials & Interfaces

Engineering Biodegradable Multifunctional Antibacterial Bioactive Nanosystem for Enhancing Tumor Photothermo-Chemotherapy and Bone Regeneration

(2019) Yumeng Xue et al.   ACS Nano

Biomimetic Nanosilica–Collagen Scaffolds for In Situ Bone Regeneration: Toward a Cell‐Free, One‐Step Surgery

(2019) Shao‐Jie Wang et al.   ADVANCED MATERIALS

Periosteal matrix-derived hydrogel promotes bone repair through an early immune regulation coupled with enhanced angio- and osteogenesis

(2019) Pengcheng Qiu et al.   BIOMATERIALS

3D printing of a lithium-calcium-silicate crystal bioscaffold with dual bioactivities for osteochondral interface reconstruction

(2018) Lei Chen et al.   BIOMATERIALS

Biomimetic mineralization of carboxymethyl chitosan nanofibers with improved osteogenic activity in vitro and in vivo

(2018) Xiujuan Zhao et al.   CARBOHYDRATE POLYMERS

The roles of Wnt/β-catenin pathway in tissue development and regenerative medicine

(2018) Maryam Majidinia et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Collagen Functionalized With Graphene Oxide Enhanced Biomimetic Mineralization and in Situ Bone Defect Repair

(2018) Chuchao Zhou et al.   ACS Applied Materials & Interfaces

Three-dimensional (3D) printed scaffold and material selection for bone repair

(2018) Lei Zhang et al.   Acta Biomaterialia

Vascularized 3D printed scaffolds for promoting bone regeneration

(2018) Yufei Yan et al.   BIOMATERIALS

Extracellular signaling molecules to promote fracture healing and bone regeneration

(2015) K.D. Hankenson et al.   ADVANCED DRUG DELIVERY REVIEWS

Wnt Signaling Inhibits Osteoclast Differentiation by Activating Canonical and Noncanonical cAMP/PKA Pathways

(2015) Megan M Weivoda et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Simvastatin promotes osteogenic differentiation of mouse embryonic stem cells via canonical Wnt/β-catenin signaling

(2011) Ling Juan Qiao et al.   MOLECULES AND CELLS

Wnt Proteins Promote Bone Regeneration

(2010) S. Minear et al.   Science Translational Medicine