Osteoblast/Osteoclast and Immune Cocktail Therapy of an Exosome/Drug Delivery Multifunctional Hydrogel Accelerates Fracture Repair

A Facile Magnetic Extrusion Method for Preparing Endosome‐Derived Vesicles for Cancer Drug Delivery

(2021) Peng Guo et al.   ADVANCED FUNCTIONAL MATERIALS

Role of microRNA-335 carried by bone marrow mesenchymal stem cells-derived extracellular vesicles in bone fracture recovery

(2021) Haifeng Hu et al.   Cell Death & Disease

MiR-144-5p, an exosomal miRNA from bone marrow-derived macrophage in type 2 diabetes, impairs bone fracture healing via targeting Smad1

(2021) Dong Zhang et al.   JOURNAL OF NANOBIOTECHNOLOGY

Dual-Targeted Nanoplatform Regulating the Bone Immune Microenvironment Enhances Fracture Healing

(2021) Wu Zhou et al.   ACS Applied Materials & Interfaces

Transplantation of Human Mesenchymal Stem-Cell-Derived Exosomes Immobilized in an Adhesive Hydrogel for Effective Treatment of Spinal Cord Injury

(2020) Liming Li et al.   NANO LETTERS

M2 Macrophagy-derived exosomal miRNA-5106 induces bone mesenchymal stem cells towards osteoblastic fate by targeting salt-inducible kinase 2 and 3

(2020) Yuan Xiong et al.   JOURNAL OF NANOBIOTECHNOLOGY

Generation of Small RNA-Modulated Exosome Mimetics for Bone Regeneration

(2020) Jiabing Fan et al.   ACS Nano

Macrophage Polarization and Osteoporosis: A Review

(2020) Joseph Muñoz et al.   Nutrients

Anti-fatigue-fracture hydrogels

(2019) Shaoting Lin et al.   Science Advances

A Biomimetic Hierarchical Nanointerface Orchestrates Macrophage Polarization and Mesenchymal Stem Cell Recruitment to Promote Endogenous Bone Regeneration

(2019) Shan-Shan Jin et al.   ACS Nano

Psoralen accelerates bone fracture healing by activating both osteoclasts and osteoblasts

(2019) Tan Zhang et al.   FASEB JOURNAL

EPC ‐derived exosomes promote osteoclastogenesis through Lnc RNA ‐ MALAT 1

(2019) Yigong Cui et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Reversal of Osteoporotic Activity by Endothelial Cell-Secreted Bone Targeting and Biocompatible Exosomes

(2019) Hongyuan Song et al.   NANO LETTERS

Cyclooxygenase 2 augments osteoblastic but suppresses chondrocytic differentiation of CD90+ skeletal stem cells in fracture sites

(2019) Samiksha Wasnik et al.   Science Advances

miRNA-26a-5p Accelerates Healing via Downregulation of PTEN in Fracture Patients with Traumatic Brain Injury

(2019) Yuan Xiong et al.   Molecular Therapy-Nucleic Acids

Individual Effector/Regulator T Cell Ratios Impact Bone Regeneration

(2019) Claudia Schlundt et al.   Frontiers in Immunology

Periosteal matrix-derived hydrogel promotes bone repair through an early immune regulation coupled with enhanced angio- and osteogenesis

(2019) Pengcheng Qiu et al.   BIOMATERIALS

Harnessing macrophage-mediated degradation of gelatin microspheres for spatiotemporal control of BMP2 release

(2018) Ramkumar T. Annamalai et al.   BIOMATERIALS

IRE1α Aggravates Ischemia Reperfusion Injury of Fatty Liver by Regulating Phenotypic Transformation of Kupffer Cells

(2018) Faji Yang et al.   FREE RADICAL BIOLOGY AND MEDICINE

M2 macrophages are closely associated with accelerated clavicle fracture healing in patients with traumatic brain injury: a retrospective cohort study

(2018) Ran Zhang et al.   Journal of Orthopaedic Surgery and Research

In Vitro and in Vivo RNA Inhibition by CD9-HuR Functionalized Exosomes Encapsulated with miRNA or CRISPR/dCas9

(2018) Zhelong Li et al.   NANO LETTERS

Sodium Fluoride under Dose Range of 2.4–24 μM, a Promising Osteoimmunomodulatory Agent for Vascularized Bone Formation

(2018) Shiyu Wu et al.   ACS Biomaterials-Science & Engineering

Dose-dependent effect of parathyroid hormone on fracture healing and bone formation in mice

(2017) Alexander Milstrey et al.   JOURNAL OF SURGICAL RESEARCH

Strontium-Substituted Submicrometer Bioactive Glasses Modulate Macrophage Responses for Improved Bone Regeneration

(2016) Wen Zhang et al.   ACS Applied Materials & Interfaces

Inflammation, fracture and bone repair

(2016) Florence Loi et al.   BONE

NOTCH signaling in skeletal progenitors is critical for fracture repair

(2016) Cuicui Wang et al.   JOURNAL OF CLINICAL INVESTIGATION

Osteoclast depletion with clodronate liposomes delays fracture healing in mice

(2016) Hsuan-Ni Lin et al.   JOURNAL OF ORTHOPAEDIC RESEARCH

Osteoclast-derived exosomal miR-214-3p inhibits osteoblastic bone formation

(2016) Defang Li et al.   Nature Communications

Biomaterial strategies for engineering implants for enhanced osseointegration and bone repair

(2015) Rachit Agarwal et al.   ADVANCED DRUG DELIVERY REVIEWS

IRE1α/XBP1-mediated branch of the unfolded protein response regulates osteoclastogenesis

(2015) Takahide Tohmonda et al.   JOURNAL OF CLINICAL INVESTIGATION

A review of hydrogel use in fracture healing and bone regeneration

(2014) David M. R. Gibbs et al.   Journal of Tissue Engineering and Regenerative Medicine

Gene therapy approaches to regenerating bone

(2012) Nadav Kimelman Bleich et al.   ADVANCED DRUG DELIVERY REVIEWS

Divergent allosteric control of the IRE1α endoribonuclease using kinase inhibitors

(2012) Likun Wang et al.   Nature Chemical Biology

TNF-α mediates diabetes-enhanced chondrocyte apoptosis during fracture healing and stimulates chondrocyte apoptosis Through FOXO1

(2010) Rayyan A Kayal et al.   JOURNAL OF BONE AND MINERAL RESEARCH