Steps of actin filament branch formation by Arp2/3 complex investigated with coarse-grained molecular dynamics

Structure of Arp2/3 complex at a branched actin filament junction resolved by single-particle cryo-electron microscopy

(2022) Bojian Ding et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Functions of Arp2/3 Complex in the Dynamics of Epithelial Tissues

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Biochemical and mechanical regulation of actin dynamics

(2022) Pekka Lappalainen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Rounding Out the Understanding of ACD Toxicity with the Discovery of Cyclic Forms of Actin Oligomers

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Deciphering the Molecular Terms of Arp2/3 Allosteric Regulation from All-Atom Simulations and Dynamical Network Theory

(2021) Sara Laporte et al.   Journal of Physical Chemistry Letters

Nucleation, stabilization, and disassembly of branched actin networks

(2021) Alexis M. Gautreau et al.   TRENDS IN CELL BIOLOGY

Insights into Actin Polymerization and Nucleation Using a Coarse-Grained Model

(2020) Brandon G. Horan et al.   BIOPHYSICAL JOURNAL

Cryo-EM structure of NPF-bound human Arp2/3 complex and activation mechanism

(2020) Austin Zimmet et al.   Science Advances

Cryo-EM reveals the transition of Arp2/3 complex from inactive to nucleation-competent state

(2020) Mohammed Shaaban et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-electron tomography structure of Arp2/3 complex in cells reveals new insights into the branch junction

(2020) Florian Fäßler et al.   Nature Communications

Mechanism of actin polymerization revealed by cryo-EM structures of actin filaments with three different bound nucleotides

(2019) Steven Z. Chou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Computational modeling highlights the role of the disordered Formin Homology 1 domain in profilin-actin transfer

(2018) Brandon G. Horan et al.   FEBS LETTERS

Identification of Wiskott-Aldrich syndrome protein (WASP) binding sites on the branched actin filament nucleator Arp2/3 complex

(2018) Qing Luan et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sequence determinants of protein phase behavior from a coarse-grained model

(2018) Gregory L. Dignon et al.   PLoS Computational Biology

Identification of an ATP-controlled allosteric switch that controls actin filament nucleation by Arp2/3 complex

(2016) Max Rodnick-Smith et al.   Nature Communications

Structural analysis of the transitional state of Arp2/3 complex activation by two actin-bound WCAs

(2014) Malgorzata Boczkowska et al.   Nature Communications

Pathway of actin filament branch formation by Arp2/3 complex revealed by single-molecule imaging

(2013) Benjamin A. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Insertions within the Actin Core of Actin-related Protein 3 (Arp3) Modulate Branching Nucleation by Arp2/3 Complex

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Key Structural Features of the Actin Filament Arp2/3 Complex Branch Junction Revealed by Molecular Simulation

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Structural and biochemical characterization of two binding sites for nucleation-promoting factor WASp-VCA on Arp2/3 complex

(2011) S.-C. Ti et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Arp2/3 complex is bound and activated by two WASP proteins

(2011) S. B. Padrick et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Dynamics Simulations of Arp2/3 Complex Activation

(2010) Paul Dalhaimer et al.   BIOPHYSICAL JOURNAL

An actin-filament-binding interface on the Arp2/3 complex is critical for nucleation and branch stability

(2010) E. D. Goley et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Accurate and efficient methods for modeling colloidal mixtures in an explicit solvent using molecular dynamics

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Hierarchical Regulation of WASP/WAVE Proteins

(2008) Shae B. Padrick et al.   MOLECULAR CELL

Coarse-grained Models for Simulations of Multiprotein Complexes: Application to Ubiquitin Binding

(2007) Young C. Kim et al.   JOURNAL OF MOLECULAR BIOLOGY