AdipoRon Inhibits Neuroinflammation Induced by Deep Hypothermic Circulatory Arrest Involving the AMPK/NF-κB Pathway in Rats

Overexpression of S100A9 in obesity impairs macrophage differentiation via TLR4-NFkB-signaling worsening inflammation and wound healing

(2022) Sandra Franz et al.   Theranostics

Integrating Gemcitabine-Based Therapy With AdipoRon Enhances Growth Inhibition in Human PDAC Cell Lines

(2022) Angela Ragone et al.   Frontiers in Pharmacology

The Function of NF-Kappa B During Epilepsy, a Potential Therapeutic Target

(2022) Mengtan Cai et al.   Frontiers in Neuroscience

Triptolide improves neurobehavioral functions, inflammation, and oxidative stress in rats under deep hypothermic circulatory arrest

(2021) Qiang Chen et al.   Aging-US

AdipoRon Attenuates Inflammation and Impairment of Cardiac Function Associated With Cardiopulmonary Bypass–Induced Systemic Inflammatory Response Syndrome

(2021) Alexander Jenke et al.   Journal of the American Heart Association

AdipoRon, an Orally Active, Synthetic Agonist of AdipoR1 and AdipoR2 Receptors Has Gastroprotective Effect in Experimentally Induced Gastric Ulcers in Mice

(2021) Hubert Zatorski et al.   MOLECULES

Neuroinflammatory In Vitro Cell Culture Models and the Potential Applications for Neurological Disorders

(2021) Ye Peng et al.   Frontiers in Pharmacology

Analysis of risk factors of cerebral complications after Stanford type A aortic dissection involving arch surgery

(2021) Yanyan Song et al.   Asian Journal of Surgery

Beneficial effects of chlorogenic acid treatment on neuroinflammation after deep hypothermic circulatory arrest may be mediated through CYLD/NF-κB signaling

(2021) Qiang Chen et al.   BRAIN RESEARCH

AdipoRon and Other Adiponectin Receptor Agonists as Potential Candidates in Cancer Treatments

(2021) Ersilia Nigro et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Diacerein versus adipoRon as adiponectin modulators in experimentally-induced end-stage type 2 diabetes mellitus in rats

(2021) Mahmoud M. Samaha et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Incidence, Risk Factors and Outcomes of Postoperative Headache After Stanford Type a Acute Aortic Dissection Surgery

(2021) Dashuai Wang et al.   Frontiers in Cardiovascular Medicine

Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer’s disease mouse model

(2020) Roy Chun-Laam Ng et al.   MOLECULAR PSYCHIATRY

Deep Hypothermic Circulatory Arrest Activates Neural Precursor Cells in the Neonatal Brain

(2020) Luca Centola et al.   ANNALS OF THORACIC SURGERY

Discovery of AdipoRon analogues as novel AMPK activators without inhibiting mitochondrial complex I

(2020) Geng Sun et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

AdipoRon improves cognitive dysfunction of Alzheimer’s disease and rescues impaired neural stem cell proliferation through AdipoR1/AMPK pathway

(2020) Bin Liu et al.   EXPERIMENTAL NEUROLOGY

AdipoRon, an adiponectin receptor agonist, protects contrast-induced nephropathy by suppressing oxidative stress and inflammation via activation of the AMPK pathway

(2020) Daqian Gu et al.   Clinical and Experimental Nephrology

NRF2, a Transcription Factor for Stress Response and Beyond

(2020) Feng He et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Adiponectin receptor agonist AdipoRon induces apoptotic cell death and suppresses proliferation in human ovarian cancer cells

(2019) Amin A. Ramzan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

The Neuroprotective Effect of the Adiponectin Receptor Agonist AdipoRon on Glutamate-Induced Cell Death in Rat Primary Retinal Ganglion Cells

(2019) Takatoshi Uchida et al.   JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS

A novel target to reduce microglial inflammation and neuronal damage after deep hypothermic circulatory arrest

(2019) Mingyue Liu et al.   JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY

AdipoRon Attenuates Neuroinflammation After Intracerebral Hemorrhage Through AdipoR1-AMPK Pathway

(2019) Jingwei Zheng et al.   NEUROSCIENCE

Resveratrol attenuates neuroinflammation after deep hypothermia with circulatory arrest in rats

(2019) Qiang Chen et al.   BRAIN RESEARCH BULLETIN

Severe systemic inflammatory response syndrome in patients following Total aortic arch replacement with deep hypothermic circulatory arrest

(2019) Jun Li et al.   Journal of Cardiothoracic Surgery

Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine†

(2018) Constantine D Mavroudis et al.   EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY

The role of deep hypothermic circulatory arrest in surgery for renal or adrenal tumor with vena cava thrombus: a single-institution experience

(2018) Peng Zhu et al.   Journal of Cardiothoracic Surgery

Activating Adiponectin Signaling with Exogenous AdipoRon Reduces Myelin Lipid Accumulation and Suppresses Macrophage Recruitment after Spinal Cord Injury

(2018) Qishuang Zhou et al.   JOURNAL OF NEUROTRAUMA

The Role of the Transcription Factor Nuclear Factor-kappa B in Thyroid Autoimmunity and Cancer

(2018) Cesidio Giuliani et al.   Frontiers in Endocrinology

Globular Adiponectin Limits Microglia Pro-Inflammatory Phenotype through an AdipoR1/NF-κB Signaling Pathway

(2017) Sarah Nicolas et al.   Frontiers in Cellular Neuroscience

AMP-activated protein kinase: a cellular energy sensor that comes in 12 flavours

(2016) Fiona A. Ross et al.   FEBS Journal

AdipoRon, the first orally active adiponectin receptor activator, attenuates postischemic myocardial apoptosis through both AMPK-mediated and AMPK-independent signalings

(2015) Yanqing Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

A cardiopulmonary bypass with deep hypothermic circulatory arrest rat model for the investigation of the systemic inflammation response and induced organ damage

(2014) Melanie Engels et al.   Journal of Inflammation-London

A small-molecule AdipoR agonist for type 2 diabetes and short life in obesity

(2013) Miki Okada-Iwabu et al.   NATURE

Ronning After the Adiponectin Receptors

(2013) W. L. Holland et al.   SCIENCE

The high Nrf2 expression in human acute myeloid leukemia is driven by NF- B and underlies its chemo-resistance

(2012) S. A. Rushworth et al.   BLOOD

Microglia/Macrophage Polarization Dynamics Reveal Novel Mechanism of Injury Expansion After Focal Cerebral Ischemia

(2012) Xiaoming Hu et al.   STROKE

Circulatory arrest versus cerebral perfusion during pulmonary endarterectomy surgery (PEACOG): a randomised controlled trial

(2011) Alain Vuylsteke et al.   LANCET

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

Reperfusion Injury, Microvascular Dysfunction, and Cardioprotection

(2009) Abhiram Prasad et al.   CIRCULATION

Adiponectin Decreases C-Reactive Protein Synthesis and Secretion From Endothelial Cells

(2008) Sridevi Devaraj et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY