The Dynamics of Cryptococcus neoformans Cell and Transcriptional Remodeling during Infection

Lineages Derived from Cryptococcus neoformans Type Strain H99 Support a Link between the Capacity to Be Pleomorphic and Virulence

(2022) Kenya E. Fernandes et al.   mBio

A dissemination-prone morphotype enhances extrapulmonary organ entry by Cryptococcus neoformans

(2022) Steven T. Denham et al.   Cell Host & Microbe

The global burden of HIV-associated cryptococcal infection in adults in 2020: a modelling analysis

(2022) Radha Rajasingham et al.   LANCET INFECTIOUS DISEASES

Epigenetic regulation of virulence and the transcription of ribosomal protein genes involves a YEATS family protein in Cryptococcus deneoformans

(2021) Chenxi Li et al.   FEMS YEAST RESEARCH

Ubiquitination and the Proteasome as Drug Targets in Trypanosomatid Diseases

(2021) Marie-José Bijlmakers   Frontiers in Chemistry

Inositol Metabolism Regulates Capsule Structure and Virulence in the Human Pathogen Cryptococcus neoformans

(2021) Yina Wang et al.   mBio

The Proteasome Governs Fungal Morphogenesis via Functional Connections with Hsp90 and cAMP-Protein Kinase A Signaling

(2020) Saif Hossain et al.   mBio

Monitoring Glycolysis and Respiration Highlights Metabolic Inflexibility of Cryptococcus neoformans

(2020) Sophie Lev et al.   Pathogens

Unveil the transcriptional landscape at the Cryptococcus-host axis in mice and nonhuman primates

(2019) Hailong Li et al.   PLoS Neglected Tropical Diseases

TNF-α-Producing Cryptococcus neoformans Exerts Protective Effects on Host Defenses in Murine Pulmonary Cryptococcosis

(2019) Zhenzong Fa et al.   Frontiers in Immunology

Translational Regulation Promotes Oxidative Stress Resistance in the Human Fungal Pathogen Cryptococcus neoformans

(2019) Jay Leipheimer et al.   mBio

ShinyGO: a graphical gene-set enrichment tool for animals and plants

(2019) Steven Xijin Ge et al.   BIOINFORMATICS

The Cryptococcus neoformans Titan cell is an inducible and regulated morphotype underlying pathogenesis

(2018) Ivy M. Dambuza et al.   PLoS Pathogens

Cryptococcus neoformans urease affects the outcome of intracellular pathogenesis by modulating phagolysosomal pH

(2018) Man Shun Fu et al.   PLoS Pathogens

Genotypic and Phenotypic Diversity of Cryptococcus gattii VGII Clinical Isolates and Its Impact on Virulence

(2018) Vanessa A. Barcellos et al.   Frontiers in Microbiology

Small and Large Ribosomal Subunit Deficiencies Lead to Distinct Gene Expression Signatures that Reflect Cellular Growth Rate

(2018) Ze Cheng et al.   MOLECULAR CELL

Influenza A Virus as a Predisposing Factor for Cryptococcosis

(2017) Lorena V. N. Oliveira et al.   Frontiers in Cellular and Infection Microbiology

The environmental yeast Cryptococcus liquefaciens produces capsular and secreted polysaccharides with similar pathogenic properties to those of C. neoformans

(2017) Glauber R. de S. Araújo et al.   Scientific Reports

High-dose fluconazole in combination with amphotericin B is more efficient than monotherapy in murine model of cryptococcosis

(2017) Julliana Ribeiro Alves Santos et al.   Scientific Reports

Analysis of the Protein Kinase A-Regulated Proteome of Cryptococcus neoformans Identifies a Role for the Ubiquitin-Proteasome Pathway in Capsule Formation

(2016) J. M. H. Geddes et al.   mBio

Identification of a major IP5 kinase in Cryptococcus neoformans confirms that PP-IP5/IP7, not IP6, is essential for virulence

(2016) Cecilia Li et al.   Scientific Reports

Species in the Cryptococcus gattii Complex Differ in Capsule and Cell Size following Growth under Capsule-Inducing Conditions

(2016) Kenya E. Fernandes et al.   mSphere

Heteroresistance to Itraconazole Alters the Morphology and Increases the Virulence of Cryptococcus gattii

(2015) Gabriella Freitas Ferreira et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The morphotype heterogeneity in Cryptococcus neoformans

(2015) Linqi Wang et al.   CURRENT OPINION IN MICROBIOLOGY

Virulence mechanisms and Cryptococcus neoformans pathogenesis

(2015) J. Andrew Alspaugh   FUNGAL GENETICS AND BIOLOGY

Cryptococcus: from environmental saprophyte to global pathogen

(2015) Robin C. May et al.   NATURE REVIEWS MICROBIOLOGY

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Cryptococcus gattii Infections

(2014) Sharon C.-A. Chen et al.   CLINICAL MICROBIOLOGY REVIEWS

Fluconazole Alters the Polysaccharide Capsule of Cryptococcus gattii and Leads to Distinct Behaviors in Murine Cryptococcosis

(2014) Julliana Ribeiro Alves Santos et al.   PLoS One

The Cryptococcus neoformans Transcriptome at the Site of Human Meningitis

(2014) Y. Chen et al.   mBio

Capsule Growth in Cryptococcus neoformans Is Coordinated with Cell Cycle Progression

(2014) R. Garcia-Rodas et al.   mBio

Cryptococcus neoformans and Cryptococcus gattii, the Etiologic Agents of Cryptococcosis

(2014) K. J. Kwon-Chung et al.   Cold Spring Harbor Perspectives in Medicine

featureCounts: an efficient general purpose program for assigning sequence reads to genomic features

(2013) Y. Liao et al.   BIOINFORMATICS

The Transcriptional Response of Cryptococcus neoformans to Ingestion by Acanthamoeba castellanii and Macrophages Provides Insights into the Evolutionary Adaptation to the Mammalian Host

(2013) Lorena da S. Derengowski et al.   EUKARYOTIC CELL

The role of oxidative and nitrosative bursts caused by azoles and amphotericin B against the fungal pathogen Cryptococcus gattii

(2013) G. F. Ferreira et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Global Transcriptome Profile of Cryptococcus neoformans during Exposure to Hydrogen Peroxide Induced Oxidative Stress

(2013) Rajendra Upadhya et al.   PLoS One

The Glucose Sensor-Like Protein Hxs1 Is a High-Affinity Glucose Transporter and Required for Virulence in Cryptococcus neoformans

(2013) Tong-Bao Liu et al.   PLoS One

Factors Required for Activation of Urease as a Virulence Determinant in Cryptococcus neoformans

(2013) A. Singh et al.   mBio

Brain Inositol Is a Novel Stimulator for Promoting Cryptococcus Penetration of the Blood-Brain Barrier

(2013) Tong-Bao Liu et al.   PLoS Pathogens

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Titan Cells Confer Protection from Phagocytosis in Cryptococcus neoformans Infections

(2012) Laura H. Okagaki et al.   EUKARYOTIC CELL

Titan Cell Production Enhances the Virulence of Cryptococcus neoformans

(2012) Juliet N. Crabtree et al.   INFECTION AND IMMUNITY

A murine model of Cryptococcus gattii meningoencephalitis

(2012) G. R. Thompson et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Capsules from Pathogenic and Non-Pathogenic Cryptococcus spp. Manifest Significant Differences in Structure and Ability to Protect against Phagocytic Cells

(2012) Glauber de S. Araujo et al.   PLoS One

Minimization of Bacterial Size Allows for Complement Evasion and Is Overcome by the Agglutinating Effect of Antibody

(2011) Ankur B. Dalia et al.   Cell Host & Microbe

Characterization of inositol phospho-sphingolipid-phospholipase C 1 (Isc1) inCryptococcus neoformansreveals unique biochemical features

(2011) Jennifer Henry et al.   FEBS LETTERS

Evaluation of the detection of melanin by the Fontana-Masson silver stain in tissue with a wide range of organisms including Cryptococcus

(2011) Justin A. Bishop et al.   HUMAN PATHOLOGY

Spores as Infectious Propagules of Cryptococcus neoformans

(2009) R. Velagapudi et al.   INFECTION AND IMMUNITY

Cryptococcus neoformans: Morphogenesis, infection, and evolution

(2009) Xiaorong Lin   INFECTION GENETICS AND EVOLUTION

Metabolic adaptation inCryptococcus neoformansduring early murine pulmonary infection

(2008) Guanggan Hu et al.   MOLECULAR MICROBIOLOGY

Dose translation from animal to human studies revisited

(2007) Shannon Reagan-Shaw et al.   FASEB JOURNAL