Combined loss of the BH3-only proteins Bim and Bmf restores B-cell development and function in TACI-Ig transgenic mice

Deregulated cell death and lymphocyte homeostasis cause premature lethality in mice lacking the BH3-only proteins Bim and Bmf

(2014) V. Labi et al.   BLOOD

Combined inhibition of PI3K-related DNA damage response kinases and mTORC1 induces apoptosis in MYC-driven B-cell lymphomas

(2013) J. Shortt et al.   BLOOD

The BAFF/APRIL system: Emerging functions beyond B cell biology and autoimmunity

(2013) Fabien B. Vincent et al.   CYTOKINE & GROWTH FACTOR REVIEWS

Mcl-1 is essential for the survival of plasma cells

(2013) Victor Peperzak et al.   NATURE IMMUNOLOGY

Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy

(2013) Peter E. Czabotar et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Targeting antiapoptotic A1/Bfl-1 by in vivo RNAi reveals multiple roles in leukocyte development in mice

(2012) E. Ottina et al.   BLOOD

Bcl-2, Bcl-xL, and Bcl-w are not equivalent targets of ABT-737 and navitoclax (ABT-263) in lymphoid and leukemic cells

(2012) D. Merino et al.   BLOOD

Mutual antagonism of TGF-beta and Interleukin-2 in cell survival and lineage commitment of induced regulatory T cells

(2012) D Tischner et al.   CELL DEATH AND DIFFERENTIATION

Self-recognition and clonal selection: autoreactivity drives the generation of B cells

(2012) Sebastian Herzog et al.   CURRENT OPINION IN IMMUNOLOGY

Minor cell-death defects but reduced tumor latency in mice lacking the BH3-only proteins Bad and Bmf

(2012) F Baumgartner et al.   ONCOGENE

BH3-only protein Bmf mediates apoptosis upon inhibition of CAP-dependent protein synthesis

(2010) F Grespi et al.   CELL DEATH AND DIFFERENTIATION

B-cell stage and context-dependent requirements for survival signals from BAFF and the B-cell receptor

(2010) Fabienne Mackay et al.   IMMUNOLOGICAL REVIEWS

BAFF Receptor Signaling Aids the Differentiation of Immature B Cells into Transitional B Cells following Tonic BCR Signaling

(2010) S. L. Rowland et al.   JOURNAL OF IMMUNOLOGY

Bcl-2-regulated cell death signalling in the prevention of autoimmunity

(2010) D Tischner et al.   Cell Death & Disease

Autoinhibition and adapter function of Syk

(2009) Yogesh Kulathu et al.   IMMUNOLOGICAL REVIEWS

Checkpoints in lymphocyte development and autoimmune disease

(2009) Harald von Boehmer et al.   NATURE IMMUNOLOGY

Bim and Bmf in tissue homeostasis and malignant disease

(2009) J D Piñon et al.   ONCOGENE

B-cell activating factor receptor deficiency is associated with an adult-onset antibody deficiency syndrome in humans

(2009) K. Warnatz et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells

(2008) E. Belnoue et al.   BLOOD

Peripheral B cell subsets

(2008) David Allman et al.   CURRENT OPINION IN IMMUNOLOGY

Loss of the BH3-only protein Bmf impairs B cell homeostasis and accelerates γ irradiation–induced thymic lymphoma development

(2008) Verena Labi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

BAFF activates Akt and Erk through BAFF-R in an IKK1-dependent manner in primary mouse B cells

(2008) K. L. Otipoby et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival

(2007) R. T. Woodland et al.   BLOOD