N-acetylcysteine for prevention and treatment of COVID-19: Current state of evidence and future directions

Use of N-Acetylcysteine at high doses as an oral treatment for patients hospitalized with COVID-19

(2022) José Luis Izquierdo et al.   SCIENCE PROGRESS

The Role of Oxidative Stress in Skeletal Muscle Myogenesis and Muscle Disease

(2022) Di Lian et al.   Antioxidants

N-acetylcysteine (NAC) and Hydrogen Sulfide (H2S) in Coronavirus Disease 2019 (COVID-19)

(2021) Arno R. Bourgonje et al.   ANTIOXIDANTS & REDOX SIGNALING

Antioxidants and pentoxifylline as coadjuvant measures to standard therapy to improve prognosis of patients with pneumonia by COVID-19

(2021) Adrián Palacios Chavarria et al.   Computational and Structural Biotechnology Journal

Effect of N-Acetylcysteine Administration on 30-Day Mortality in Critically Ill Patients with Septic Shock Caused by Carbapenem-Resistant Klebsiella pneumoniae and Acinetobacter baumannii: A Retrospective Case-Control Study

(2021) Alessandra Oliva et al.   Antibiotics-Basel

N-acetylcysteine for the treatment of COVID-19 among hospitalized patients

(2021) Sergey N. Avdeev et al.   JOURNAL OF INFECTION

Use of Thiols in the Treatment of COVID-19: Current Evidence

(2021) Mario Cazzola et al.   LUNG

A pilot study on intravenous N-Acetylcysteine treatment in patients with mild-to-moderate COVID19-associated acute respiratory distress syndrome

(2021) Abbas Taher et al.   Pharmacological Reports

N-acetyl-cysteine reduces the risk for mechanical ventilation and mortality in patients with COVID-19 pneumonia: a two-center retrospective cohort study

(2021) Stelios F. Assimakopoulos et al.   Infectious Diseases

N-Acetylcysteine as Adjuvant Therapy for COVID-19 – A Perspective on the Current State of the Evidence

(2021) Kon Ken Wong et al.   Journal of Inflammation Research

The Potential Role of Cytokine Storm Pathway in the Clinical Course of Viral Respiratory Pandemic

(2021) Giuseppe Murdaca et al.   Biomedicines

N-Acetylcysteine for Cardiac Protection During Coronary Artery Reperfusion: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

(2021) Sher Ali Khan et al.   Frontiers in Cardiovascular Medicine

Nutraceuticals have potential for boosting the type 1 interferon response to RNA viruses including influenza and coronavirus

(2020) Mark F. McCarty et al.   PROGRESS IN CARDIOVASCULAR DISEASES

The species Severe acute respiratory syndrome-related coronavirus: classifying 2019-nCoV and naming it SARS-CoV-2

(2020)   Nature Microbiology

SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor

(2020) Markus Hoffmann et al.   CELL

COVID‐19 and Renin‐Angiotensin system inhibition – role of angiotensin converting enzyme 2 (ACE2) ‐ Is there any scientific evidence for controversy?

(2020) Aneta Aleksova et al.   JOURNAL OF INTERNAL MEDICINE

Pulmonary fibrosis and COVID-19: the potential role for antifibrotic therapy

(2020) Peter M George et al.   Lancet Respiratory Medicine

Rationale for the use of N -acetylcysteine in both prevention and adjuvant therapy of COVID-19

(2020) Silvio De Flora et al.   FASEB JOURNAL

N-acetylcysteine as a potential treatment for novel coronavirus disease 2019

(2020) Rangel-Méndez Jorge-Aarón et al.   Future Microbiology

Protective effects of N-acetylcysteine on a chemical-induced murine model of asthma

(2020) Jiafu Song et al.   JOURNAL OF ASTHMA

N-acetyl-cysteine may prevent COVID-19-associated cytokine storm and acute respiratory distress syndrome

(2020) Stelios F. Assimakopoulos et al.   MEDICAL HYPOTHESES

Factors associated with COVID-19-related death using OpenSAFELY

(2020) Elizabeth J. Williamson et al.   NATURE

Extrapulmonary manifestations of COVID-19

(2020) Aakriti Gupta et al.   NATURE MEDICINE

Cytokine Storm in COVID-19—Immunopathological Mechanisms, Clinical Considerations, and Therapeutic Approaches: The REPROGRAM Consortium Position Paper

(2020) Sonu Bhaskar et al.   Frontiers in Immunology

The COVID-19 Cytokine Storm; What We Know So Far

(2020) Dina Ragab et al.   Frontiers in Immunology

The Role of Glutathione in Protecting against the Severe Inflammatory Response Triggered by COVID-19

(2020) Francesca Silvagno et al.   Antioxidants

Therapeutic blockade of inflammation in severe COVID-19 infection with intravenous N-acetylcysteine

(2020) Homam Ibrahim et al.   CLINICAL IMMUNOLOGY

Double-blind, randomized, placebo-controlled trial with N-acetylcysteine for treatment of severe acute respiratory syndrome caused by COVID-19

(2020) Julio Cesar Garcia de Alencar et al.   CLINICAL INFECTIOUS DISEASES

Nox2 activation in Covid-19

(2020) Francesco Violi et al.   Redox Biology

N-acetylcysteine for adults with acute respiratory distress syndrome: A meta-analysis of randomized controlled trials

(2019) Xin Lu et al.   Hong Kong Journal of Emergency Medicine

Dual Role of Reactive Oxygen Species in Muscle Function: Can Antioxidant Dietary Supplements Counteract Age-Related Sarcopenia?

(2019) Simona Damiano et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Multifaceted activity of N-acetyl-l-cysteine in chronic obstructive pulmonary disease

(2018) Luigino Calzetta et al.   Expert Review of Respiratory Medicine

TOLLIP,MUC5B, and the Response toN-Acetylcysteine among Individuals with Idiopathic Pulmonary Fibrosis

(2015) Justin M. Oldham et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

N-acetylcysteine in COPD: why, how, and when?

(2015) Claudio M. Sanguinetti   MULTIDISCIPLINARY RESPIRATORY MEDICINE

Redox outside the Box: Linking Extracellular Redox Remodeling with Intracellular Redox Metabolism

(2011) Ruma Banerjee   JOURNAL OF BIOLOGICAL CHEMISTRY

The role of glutathione-S-transferase polymorphisms on clinical outcome of ALI/ARDS patient treated with N-acetylcysteine

(2008) Mandana Moradi et al.   RESPIRATORY MEDICINE