Polo-like kinase 1 inhibits DNA damage response during mitosis

Cdk1-dependent regulation of the Mre11 complex couples DNA repair pathways to cell cycle progression

(2014) Antoine Simoneau et al.   CELL CYCLE

Histone H4 Lys 20 Monomethylation of the CENP-A Nucleosome Is Essential for Kinetochore Assembly

(2014) Tetsuya Hori et al.   DEVELOPMENTAL CELL

USP28 Is Recruited to Sites of DNA Damage by the Tandem BRCT Domains of 53BP1 but Plays a Minor Role in Double-Strand Break Metabolism

(2014) P. A. Knobel et al.   MOLECULAR AND CELLULAR BIOLOGY

Dephosphorylation Enables the Recruitment of 53BP1 to Double-Strand DNA Breaks

(2014) Dong-Hyun Lee et al.   MOLECULAR CELL

Dub3 controls DNA damage signalling by direct deubiquitination of H2AX

(2014) M. Rocío Delgado-Díaz et al.   Molecular Oncology

Mitosis Inhibits DNA Double-Strand Break Repair to Guard Against Telomere Fusions

(2014) A. Orthwein et al.   SCIENCE

Downregulation of Wip1 phosphatase modulates the cellular threshold of DNA damage signaling in mitosis

(2013) Libor Macurek et al.   CELL CYCLE

Ubp-M serine 552 phosphorylation by cyclin-dependent kinase 1 regulates cell cycle progression

(2013) Yang Xu et al.   CELL CYCLE

USP3 counteracts RNF168 via deubiquitinating H2A and γH2AX at lysine 13 and 15

(2013) Nidhi Sharma et al.   CELL CYCLE

The Deubiquitylating Enzyme USP44 Counteracts the DNA Double-strand Break Response Mediated by the RNF8 and RNF168 Ubiquitin Ligases

(2013) Anna Mosbech et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection

(2013) J. Ross Chapman et al.   MOLECULAR CELL

A Cell Cycle-Dependent Regulatory Circuit Composed of 53BP1-RIF1 and BRCA1-CtIP Controls DNA Repair Pathway Choice

(2013) Cristina Escribano-Díaz et al.   MOLECULAR CELL

The DNA damage response during mitosis

(2013) Anne Margriet Heijink et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

53BP1 is a reader of the DNA-damage-induced H2A Lys 15 ubiquitin mark

(2013) Amélie Fradet-Turcotte et al.   NATURE

Double-strand break repair: 53BP1 comes into focus

(2013) Stephanie Panier et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

53BP1 Regulates DSB Repair Using Rif1 to Control 5' End Resection

(2013) M. Zimmermann et al.   SCIENCE

Rif1 Prevents Resection of DNA Breaks and Promotes Immunoglobulin Class Switching

(2013) M. Di Virgilio et al.   SCIENCE

53BP1: pro choice in DNA repair

(2013) Michal Zimmermann et al.   TRENDS IN CELL BIOLOGY

RNF168 Ubiquitinates K13-15 on H2A/H2AX to Drive DNA Damage Signaling

(2012) Francesca Mattiroli et al.   CELL

A novel ubiquitin mark at the N-terminal tail of histone H2As targeted by RNF168 ubiquitin ligase

(2012) Marco Gatti et al.   CELL CYCLE

A telomere-dependent DNA damage checkpoint induced by prolonged mitotic arrest

(2012) Makoto T Hayashi et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Switching Polo-like kinase-1 on and off in time and space

(2012) Wytse Bruinsma et al.   TRENDS IN BIOCHEMICAL SCIENCES

Give me a break, but not in mitosis

(2011) Simona Giunta et al.   CELL CYCLE

DNA Damage Response Is Suppressed by the High Cyclin-dependent Kinase 1 Activity in Mitotic Mammalian Cells

(2011) Wei Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Replication stress induces 53BP1-containing OPT domains in G1 cells

(2011) Jeanine A. Harrigan et al.   JOURNAL OF CELL BIOLOGY

53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

(2011) Claudia Lukas et al.   NATURE CELL BIOLOGY

Checkpoint control and cancer

(2011) R H Medema et al.   ONCOGENE

DNA damage foci in mitosis are devoid of 53BP1

(2010) Glyn Nelson et al.   CELL CYCLE

DNA damage signaling in response to double-strand breaks during mitosis

(2010) Simona Giunta et al.   JOURNAL OF CELL BIOLOGY

The Plk1-dependent Phosphoproteome of the Early Mitotic Spindle

(2010) Anna Santamaria et al.   MOLECULAR & CELLULAR PROTEOMICS

P38 Mitogen-activated Protein Kinase Activity Is Required during Mitosis for Timely Satisfaction of the Mitotic Checkpoint But Not for the Fidelity of Chromosome Segregation

(2010) Kyunghee Lee et al.   MOLECULAR BIOLOGY OF THE CELL

53BP1-dependent robust localized KAP-1 phosphorylation is essential for heterochromatic DNA double-strand break repair

(2010) Angela T. Noon et al.   NATURE CELL BIOLOGY

Quantitative Phosphoproteomics Reveals Widespread Full Phosphorylation Site Occupancy During Mitosis

(2010) J. V. Olsen et al.   Science Signaling

A Mitotic Phosphorylation Feedback Network Connects Cdk1, Plk1, 53BP1, and Chk2 to Inactivate the G2/M DNA Damage Checkpoint

(2010) Marcel A. T. M. van Vugt et al.   PLOS BIOLOGY

RNF168 Binds and Amplifies Ubiquitin Conjugates on Damaged Chromosomes to Allow Accumulation of Repair Proteins

(2009) Carsten Doil et al.   CELL

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Polo-like kinase 1 reaches beyond mitosis—cytokinesis, DNA damage response, and development

(2008) Tohru Takaki et al.   CURRENT OPINION IN CELL BIOLOGY

Polo on the Rise—from Mitotic Entry to Cytokinesis with Plk1

(2008) Mark Petronczki et al.   DEVELOPMENTAL CELL

Plk1- and β-TrCP–dependent degradation of Bora controls mitotic progression

(2008) Akiko Seki et al.   JOURNAL OF CELL BIOLOGY

53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility

(2008) Nadya Dimitrova et al.   NATURE

Polo-like kinase-1 is activated by aurora A to promote checkpoint recovery

(2008) Libor Macůrek et al.   NATURE

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA