Spatiotemporal local and abscopal cell death and immune responses to histotripsy focused ultrasound tumor ablation

CD8+ T cells and fatty acids orchestrate tumor ferroptosis and immunity via ACSL4

(2022) Peng Liao et al.   CANCER CELL

Programmed Cell Death Tunes Tumor Immunity

(2022) Jing Liu et al.   Frontiers in Immunology

Combination of Radiofrequency Ablation With Resiquimod to Treat Hepatocellular Carcinoma Via Inflammation of Tumor Immune Microenvironment and Suppression of Angiogenesis

(2022) Zhou Tian et al.   Frontiers in Oncology

Ionizing radiation triggers the antitumor immunity by inducing GSDME-mediated pyroptosis in tumor cells

(2022) Wei Cao et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Clinical Implications of Necroptosis Genes Expression for Cancer Immunity and Prognosis: A Pan-Cancer Analysis

(2022) Xin-yu Li et al.   Frontiers in Immunology

Clinical application status and prospect of the combined anti-tumor strategy of ablation and immunotherapy

(2022) Li Yin et al.   Frontiers in Immunology

Immune modulation resulting from MR-guided high intensity focused ultrasound in a model of murine breast cancer

(2021) Brett Z. Fite et al.   Scientific Reports

Liver Histotripsy Mediated Abscopal Effect—Case Report

(2021) Joan Vidal-Jove et al.   IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL

Histotripsy Ablation Alters the Tumor Microenvironment and Promotes Immune System Activation in a Subcutaneous Model of Pancreatic Cancer

(2021) Alissa Hendricks-Wenger et al.   IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL

Tumor-killing nanoreactors fueled by tumor debris can enhance radiofrequency ablation therapy and boost antitumor immune responses

(2021) Zhijuan Yang et al.   Nature Communications

Immunological Effects of Histotripsy for Cancer Therapy

(2021) Alissa Hendricks-Wenger et al.   Frontiers in Oncology

Immunogenic ferroptosis and where to find it?

(2021) Robin Demuynck et al.   Journal for ImmunoTherapy of Cancer

Key necroptotic proteins are required for Smac mimetic-mediated sensitization of cholangiocarcinoma cells to TNF-α and chemotherapeutic gemcitabine-induced necroptosis

(2020) Perawatt Akara-amornthum et al.   PLoS One

Non-thermal histotripsy tumor ablation promotes abscopal immune responses that enhance cancer immunotherapy

(2020) Shibin Qu et al.   Journal for ImmunoTherapy of Cancer

Multiplex digital spatial profiling of proteins and RNA in fixed tissue

(2020) Christopher R. Merritt et al.   NATURE BIOTECHNOLOGY

Cellular cytotoxicity is a form of immunogenic cell death

(2020) Luna Minute et al.   Journal for ImmunoTherapy of Cancer

Focused Ultrasound for Immunomodulation of the Tumor Microenvironment

(2020) Jordan B. Joiner et al.   JOURNAL OF IMMUNOLOGY

The R package Rsubread is easier, faster, cheaper and better for alignment and quantification of RNA sequencing reads

(2019) Yang Liao et al.   NUCLEIC ACIDS RESEARCH

CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy

(2019) Weimin Wang et al.   NATURE

Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers

(2019) Ki Joo Pahk et al.   Scientific Reports

Radiotherapy and immunotherapy promote tumoral lipid oxidation and ferroptosis via synergistic repression of SLC7A11

(2019) Xueting Lang et al.   Cancer Discovery

The Diversification of Cell Death and Immunity: Memento Mori

(2019) Arnaud J. Legrand et al.   MOLECULAR CELL

Immunological Mechanisms Responsible for Radiation-Induced Abscopal Effect

(2018) María E. Rodríguez-Ruiz et al.   TRENDS IN IMMUNOLOGY

Distinct immune signatures in directly treated and distant tumors result from TLR adjuvants and focal ablation

(2018) Michael Chavez et al.   Theranostics

Co-transfer of tumor-specific effector and memory CD8+ T cells enhances the efficacy of adoptive melanoma immunotherapy in a mouse model

(2018) Amanda Contreras et al.   Journal for ImmunoTherapy of Cancer

Mouse Genome Database (MGD) 2019

(2018) Carol J Bult et al.   NUCLEIC ACIDS RESEARCH

Boiling Histotripsy Ablation of Renal Cell Carcinoma in the Eker Rat Promotes a Systemic Inflammatory Response

(2018) George R. Schade et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

BioJupies: Automated Generation of Interactive Notebooks for RNA-Seq Data Analysis in the Cloud

(2018) Denis Torre et al.   Cell Systems

Cell death and immunity in cancer: From danger signals to mimicry of pathogen defense responses

(2017) Abhishek D. Garg et al.   IMMUNOLOGICAL REVIEWS

Necroptotic cell death in anti-cancer therapy

(2017) Olga Krysko et al.   IMMUNOLOGICAL REVIEWS

Enhanced local and systemic anti-melanoma CD8+ T cell responses after memory T cell-based adoptive immunotherapy in mice

(2016) Amanda Contreras et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Visualizing the Histotripsy Process: Bubble Cloud–Cancer Cell Interactions in a Tissue-Mimicking Environment

(2016) Eli Vlaisavljevich et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Thermal Ablative Therapies and Immune Checkpoint Modulation: Can Locoregional Approaches Effect a Systemic Response?

(2016) Amol Mehta et al.   Gastroenterology Research and Practice

Histotripsy methods in mechanical disintegration of tissue: Towards clinical applications

(2015) Vera A. Khokhlova et al.   INTERNATIONAL JOURNAL OF HYPERTHERMIA

CTLA-4 Blockade Plus Adoptive T-Cell Transfer Promotes Optimal Melanoma Immunity in Mice

(2015) David A. Mahvi et al.   JOURNAL OF IMMUNOTHERAPY

PD-1 Restrains Radiotherapy-Induced Abscopal Effect

(2015) S. S. Park et al.   Cancer Immunology Research

Combinatorial Strategies for the Induction of Immunogenic Cell Death

(2015) Lucillia Bezu et al.   Frontiers in Immunology

The Molecular Signatures Database Hallmark Gene Set Collection

(2015) Arthur Liberzon et al.   Cell Systems

Tumor cell lysates as immunogenic sources for cancer vaccine design

(2015) Fermín E González et al.   Human Vaccines & Immunotherapeutics

Local tumour ablative therapies: Opportunities for maximising immune engagement and activation

(2014) Morgan A. O'Brien et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Cell-Death-Associated Molecular Patterns As Determinants of Cancer Immunogenicity

(2013) Sylvain Ladoire et al.   ANTIOXIDANTS & REDOX SIGNALING

Defective immunogenic cell death of HMGB1-deficient tumors: compensatory therapy with TLR4 agonists

(2013) T Yamazaki et al.   CELL DEATH AND DIFFERENTIATION

Oncology Meets Immunology: The Cancer-Immunity Cycle

(2013) Daniel S. Chen et al.   IMMUNITY

STAR: ultrafast universal RNA-seq aligner

(2012) Alexander Dobin et al.   BIOINFORMATICS

Memory T cells are uniquely resistant to melanoma-induced suppression

(2012) Lucy Wentworth et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

High-Intensity Focused Ultrasound Tumor Ablation Activates Autologous Tumor-Specific Cytotoxic T Lymphocytes

(2012) Ji-Zhu Xia et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Melanoma-induced suppression of tumor antigen-specific T cell expansion is comparable to suppression of global T cell expansion

(2011) Andrew J. Russ et al.   CELLULAR IMMUNOLOGY

Changes in interleukin-1β and 6 after hepatic microwave tissue ablation compared with radiofrequency, cryotherapy and surgical resections

(2010) Fateh Ahmad et al.   AMERICAN JOURNAL OF SURGERY

Rate of Freeze Alters the Immunologic Response After Cryoablation of Breast Cancer

(2009) Michael S. Sabel et al.   ANNALS OF SURGICAL ONCOLOGY

Quantitative ultrasound backscatter for pulsed cavitational ultrasound therapy-histotripsy

(2009) T.-y. Wang et al.   IEEE TRANSACTIONS ON ULTRASONICS FERROELECTRICS AND FREQUENCY CONTROL

Induction of Immunological Tolerance by Apoptotic Cells Requires Caspase-Dependent Oxidation of High-Mobility Group Box-1 Protein

(2008) Hirotaka Kazama et al.   IMMUNITY