Tumor cell lysates as immunogenic sources for cancer vaccine design

Melanoma cell lysate induces CCR7 expression andin vivomigration to draining lymph nodes of therapeutic human dendritic cells

(2014) Fermín E. González et al.   IMMUNOLOGY

Dendritic cell immunotherapy

(2013) Rachel Lubong Sabado et al.   Annals of the New York Academy of Sciences

A Review of Dendritic Cell Therapy for Cancer: Progress and Challenges

(2013) Gina M. Mantia-Smaldone et al.   BIODRUGS

Tumour cell lysate-loaded dendritic cell vaccine induces biochemical and memory immune response in castration-resistant prostate cancer patients

(2013) D Reyes et al.   BRITISH JOURNAL OF CANCER

A Dendritic Cell Vaccine Pulsed with Autologous Hypochlorous Acid-Oxidized Ovarian Cancer Lysate Primes Effective Broad Antitumor Immunity: From Bench to Bedside

(2013) C. L.-L. Chiang et al.   CLINICAL CANCER RESEARCH

Safety and Tumor Responses with Lambrolizumab (Anti–PD-1) in Melanoma

(2013) Omid Hamid et al.   NEW ENGLAND JOURNAL OF MEDICINE

Trial Watch

(2013) Erika Vacchelli et al.   OncoImmunology

Immunotherapy of cancer in 2012

(2012) John M. Kirkwood et al.   CA-A CANCER JOURNAL FOR CLINICIANS

The immunological response and post-treatment survival of DC-vaccinated melanoma patients are associated with increased Th1/Th17 and reduced Th3 cytokine responses

(2012) Claudia Durán-Aniotz et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

Toll-like receptor 4 gene polymorphism influences dendritic cell in vitro function and clinical outcomes in vaccinated melanoma patients

(2012) Andrés Tittarelli et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

A novel pathway combining calreticulin exposure and ATP secretion in immunogenic cancer cell death

(2012) Abhishek D Garg et al.   EMBO JOURNAL

Metastatic melanoma: the new era of targeted therapy

(2012) Michele Guida et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

F-Actin Is an Evolutionarily Conserved Damage-Associated Molecular Pattern Recognized by DNGR-1, a Receptor for Dead Cells

(2012) Susan Ahrens et al.   IMMUNITY

Characterization of resident and migratory dendritic cells in human lymph nodes

(2012) Elodie Segura et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Immunomodulating antibodies in the treatment of metastatic melanoma: The experience with anti-CTLA-4, anti-CD137, and anti-PD1

(2012) Ester Simeone et al.   Journal of Immunotoxicology

Ipilimumab in advanced melanoma

(2012) Alberto Farolfi et al.   MELANOMA RESEARCH

Immunotherapy in ovarian cancer

(2012) Gina M. Mantia-Smaldone et al.   Human Vaccines & Immunotherapeutics

Human Tumor Cells Killed by Anthracyclines Induce a Tumor-Specific Immune Response

(2011) J. Fucikova et al.   CANCER RESEARCH

Heat-Shock Induction of Tumor-Derived Danger Signals Mediates Rapid Monocyte Differentiation into Clinically Effective Dendritic Cells

(2011) R. Aguilera et al.   CLINICAL CANCER RESEARCH

Myeloid C-type Lectin Receptors in Pathogen Recognition and Host Defense

(2011) Fabiola Osorio et al.   IMMUNITY

Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1

(2011) Paul F. Robbins et al.   JOURNAL OF CLINICAL ONCOLOGY

Emerging role of damage-associated molecular patterns derived from mitochondria in inflammation

(2011) Dmitri V. Krysko et al.   TRENDS IN IMMUNOLOGY

Therapeutic options in cutaneous melanoma: latest developments

(2011) Rodabe N. Amaria et al.   Therapeutic Advances in Medical Oncology

Microbial Stimulation Fully Differentiates Monocytes to DC-SIGN/CD209+ Dendritic Cells for Immune T Cell Areas

(2010) Cheolho Cheong et al.   CELL

Decoding Cell Death Signals in Inflammation and Immunity

(2010) Laurence Zitvogel et al.   CELL

Chemotherapy induces ATP release from tumor cells

(2010) Isabelle Martins et al.   CELL CYCLE

Therapeutic cancer vaccines: are we there yet?

(2010) Christopher A. Klebanoff et al.   IMMUNOLOGICAL REVIEWS

Features of the dendritic cell lineage

(2010) Ralph M. Steinman et al.   IMMUNOLOGICAL REVIEWS

Phase I Study of Single-Agent Anti–Programmed Death-1 (MDX-1106) in Refractory Solid Tumors: Safety, Clinical Activity, Pharmacodynamics, and Immunologic Correlates

(2010) Julie R. Brahmer et al.   JOURNAL OF CLINICAL ONCOLOGY

Characterization of human DNGR-1+BDCA3+leukocytes as putative equivalents of mouse CD8α+dendritic cells

(2010) Lionel Franz Poulin et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer

(2010) Philip W. Kantoff et al.   NEW ENGLAND JOURNAL OF MEDICINE

Immunogenic cell death modalities and their impact on cancer treatment

(2009) Oliver Kepp et al.   APOPTOSIS

Immunogenic cell death, DAMPs and anticancer therapeutics: An emerging amalgamation

(2009) Abhishek D. Garg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Human Dendritic Cells Induce the Differentiation of Interleukin-21-Producing T Follicular Helper-like Cells through Interleukin-12

(2009) Nathalie Schmitt et al.   IMMUNITY

Prolonged Survival of Dendritic Cell–Vaccinated Melanoma Patients Correlates With Tumor-Specific Delayed Type IV Hypersensitivity Response and Reduction of Tumor Growth Factor β-Expressing T Cells

(2009) Mercedes N. López et al.   JOURNAL OF CLINICAL ONCOLOGY

Independent Regulation of Chemokine Responsiveness and Cytolytic Function versus CD8+ T Cell Expansion by Dendritic Cells

(2009) P. B. Watchmaker et al.   JOURNAL OF IMMUNOLOGY

Analysis and Characterization of Antitumor T-cell Response After Administration of Dendritic Cells Loaded With Allogeneic Tumor Lysate to Metastatic Melanoma Patients

(2009) Nadege Bercovici et al.   JOURNAL OF IMMUNOTHERAPY

Optimization of Dendritic Cell Loading With Tumor Cell Lysates for Cancer Immunotherapy

(2009) Paul Hatfield et al.   JOURNAL OF IMMUNOTHERAPY

Necrotic cells trigger a sterile inflammatory response through the Nlrp3 inflammasome

(2009) S. S. Iyer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Inflammatory Response to Cell Death

(2008) Kenneth L. Rock et al.   Annual Review of Pathology-Mechanisms of Disease

Induction of Tumor-Specific CD4+ and CD8+ T-Cell Immunity in Cervical Cancer Patients by a Human Papillomavirus Type 16 E6 and E7 Long Peptides Vaccine

(2008) M. J.P. Welters et al.   CLINICAL CANCER RESEARCH

Phase I Immunotherapeutic Trial with Long Peptides Spanning the E6 and E7 Sequences of High-Risk Human Papillomavirus 16 in End-Stage Cervical Cancer Patients Shows Low Toxicity and Robust Immunogenicity

(2008) G. G. Kenter et al.   CLINICAL CANCER RESEARCH

Dendritic cell vaccines in melanoma: From promise to proof?

(2008) W.J. Lesterhuis et al.   CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY

Immunogenic cancer cell death: a key-lock paradigm

(2008) Antoine Tesniere et al.   CURRENT OPINION IN IMMUNOLOGY

Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

(2008) Martijn S. Bijker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A phase II study of adoptive immunotherapy using dendritic cells pulsed with tumor lysate in patients with hepatocellular carcinoma

(2008) Daniel H. Palmer et al.   HEPATOLOGY

Cancer Immunotherapy by Dendritic Cells

(2008) Cornelis J.M. Melief   IMMUNITY

Cancer vaccines for established cancer: how to make them better?

(2008) Daniel M. Andrews et al.   IMMUNOLOGICAL REVIEWS

Pattern recognition receptors and control of adaptive immunity

(2008) Noah W. Palm et al.   IMMUNOLOGICAL REVIEWS

Dendritic cells and cytokines in immune rejection of cancer

(2007) M FERRANTINI et al.   CYTOKINE & GROWTH FACTOR REVIEWS