Genetic and Pharmacological Inhibition of Astrocytic Mysm1 Alleviates Depressive‐Like Disorders by Promoting ATP Production

Therapeutic effects of subthalamic nucleus deep brain stimulation on anxiety and depression in Parkinson’s disease patients

(2022) Fan-Gang Meng et al.   Journal of Neurorestoratology

Loss of MYSM1 inhibits the oncogenic activity of cMYC in B cell lymphoma

(2021) Yun Hsiao Lin et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53

(2021) Yafei Guo et al.   Cell Death & Disease

Role of Mitochondrial Calcium and the Permeability Transition Pore in Regulating Cell Death

(2020) Tyler M. Bauer et al.   CIRCULATION RESEARCH

Hippocampal CD 39/ ENTPD 1 promotes mouse depression‐like behavior through hydrolyzing extracellular ATP

(2020) Qian‐Qian Cui et al.   EMBO REPORTS

AMP‐activated protein kinase (AMPK) regulates astrocyte oxidative metabolism by balancing TCA cycle dynamics

(2020) Caroline M. Voss et al.   GLIA

G-Protein-Coupled Receptors in Astrocyte–Neuron Communication

(2020) Paulo Kofuji et al.   NEUROSCIENCE

A1 astrocytes contribute to murine depression-like behavior and cognitive dysfunction, which can be alleviated by IL-10 or fluorocitrate treatment

(2020) He-Yang Zhang et al.   Journal of Neuroinflammation

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

(2020) Stephen C. Cunnane et al.   NATURE REVIEWS DRUG DISCOVERY

Further delineation of bone marrow failure syndrome caused by novel compound heterozygous variants of MYSM1

(2020) Niu Li et al.   GENE

MYSM1 Represses Innate Immunity and Autoimmunity through Suppressing the cGAS-STING Pathway

(2020) Mingfu Tian et al.   Cell Reports

MYSM1 Suppresses Cellular Senescence and the Aging Process to Prolong Lifespan

(2020) Mingfu Tian et al.   Advanced Science

Opposing effects of an atypical glycinergic and substance P transmission on interpeduncular nucleus plasticity

(2019) Riccardo Melani et al.   NEUROPSYCHOPHARMACOLOGY

The effect of fluoxetine on astrocyte autophagy flux and injured mitochondria clearance in a mouse model of depression

(2019) Xiaodong Shu et al.   Cell Death & Disease

Ketamine and depression: a narrative review

(2019) Alexandrine Corriger et al.   Drug Design Development and Therapy

Metformin ameliorates stress-induced depression-like behaviors via enhancing the expression of BDNF by activating AMPK/CREB-mediated histone acetylation

(2019) Wenting Fang et al.   JOURNAL OF AFFECTIVE DISORDERS

2A-DUB/Mysm1 Regulates Epidermal Development in Part by Suppressing p53-Mediated Programs

(2018) Christina Wilms et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Astroglial Kir4.1 in the lateral habenula drives neuronal bursts in depression

(2018) Yihui Cui et al.   NATURE

Ketamine blocks bursting in the lateral habenula to rapidly relieve depression

(2018) Yan Yang et al.   NATURE

Menin Deficiency Leads to Depressive-like Behaviors in Mice by Modulating Astrocyte-Mediated Neuroinflammation

(2018) Lige Leng et al.   NEURON

Low on energy? An energy supply-demand perspective on stress and depression

(2018) Leif Østergaard et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Resveratrol Improves the Energy Sensing and Glycolipid Metabolism of Blunt Snout Bream Megalobrama amblycephala Fed High-Carbohydrate Diets by Activating the AMPK–SIRT1–PGC-1α Network

(2018) Hua-Juan Shi et al.   Frontiers in Physiology

Depression

(2018) Gin S Malhi et al.   LANCET

Deubiquitinase Mysm1 regulates macrophage survival and polarization

(2018) Xin Zhao et al.   MOLECULAR BIOLOGY REPORTS

The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex

(2018) Swarupa Panda et al.   Nature Communications

Myb-like, SWIRM, and MPN domains 1 (MYSM1) deficiency: Genotoxic stress-associated bone marrow failure and developmental aberrations

(2017) Ehsan Bahrami et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

β-asarone inhibited cell growth and promoted autophagy via P53/Bcl-2/Bclin-1 and P53/AMPK/mTOR pathways in Human Glioma U251 cells

(2017) Nanbu Wang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Calhm2 governs astrocytic ATP releasing in the development of depression-like behaviors

(2017) M Jun et al.   MOLECULAR PSYCHIATRY

Anxiety and Nicotine Dependence: Emerging Role of the Habenulo-Interpeduncular Axis

(2017) Susanna Molas et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

MYSM1/2A-DUB is an epigenetic regulator in human melanoma and contributes to tumor cell growth

(2017) Christina Wilms et al.   Oncotarget

Aspirin Suppresses Growth in PI3K-Mutant Breast Cancer by Activating AMPK and Inhibiting mTORC1 Signaling

(2016) Whitney S. Henry et al.   CANCER RESEARCH

Deubiquitination and Activation of AMPK by USP10

(2016) Min Deng et al.   MOLECULAR CELL

Cellular and molecular basis for stress-induced depression

(2016) J-S Seo et al.   MOLECULAR PSYCHIATRY

p53 mediates loss of hematopoietic stem cell function and lymphopenia in Mysm1 deficiency

(2015) J. I. Belle et al.   BLOOD

Interplay of H2A deubiquitinase 2A-DUB/Mysm1 and the p19ARF/p53 axis in hematopoiesis, early T-cell development and tissue differentiation

(2015) M Gatzka et al.   CELL DEATH AND DIFFERENTIATION

Deubiquitinase MYSM1 Regulates Innate Immunity through Inactivation of TRAF3 and TRAF6 Complexes

(2015) Swarupa Panda et al.   IMMUNITY

An in vivo genetic reversion highlights the crucial role of Myb-Like, SWIRM, and MPN domains 1 (MYSM1) in human hematopoiesis and lymphocyte differentiation

(2015) Tangui Le Guen et al.   JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY

MYSM-1 suppresses migration and invasion in renal carcinoma through inhibiting epithelial-mesenchymal transition

(2015) Lei Zhou et al.   TUMOR BIOLOGY

The control of hematopoietic stem cell maintenance, self-renewal, and differentiation by Mysm1-mediated epigenetic regulation

(2013) T. Wang et al.   BLOOD

Aspirin: a review of its neurobiological properties and therapeutic potential for mental illness

(2013) Michael Berk et al.   BMC Medicine

Role of stress-inducible protein-1 in recruitment of bone marrow derived cells into the ischemic brains

(2013) Shin-Da Lee et al.   EMBO Molecular Medicine

Astrocyte-derived ATP modulates depressive-like behaviors

(2013) Xiong Cao et al.   NATURE MEDICINE

Role of α5* nicotinic acetylcholine receptors in the effects of acute and chronic nicotine treatment on brain reward function in mice

(2013) Christie D. Fowler et al.   PSYCHOPHARMACOLOGY

Genetic dissection of medial habenula–interpeduncular nucleus pathway function in mice

(2013) Yuki Kobayashi et al.   Frontiers in Behavioral Neuroscience

AMPK: a nutrient and energy sensor that maintains energy homeostasis

(2012) D. Grahame Hardie et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation

(2011) A. Nijnik et al.   BLOOD

Control of B Cell Development by the Histone H2A Deubiquitinase MYSM1

(2011) Xiao-Xia Jiang et al.   IMMUNITY

Amygdala circuitry mediating reversible and bidirectional control of anxiety

(2011) Kay M. Tye et al.   NATURE

Neurodevelopmental Disruption of Cortico-Striatal Function Caused by Degeneration of Habenula Neurons

(2011) Young-A Lee et al.   PLoS One

Depression and bone mass

(2010) Itai A. Bab et al.   Annals of the New York Academy of Sciences

PGC-1α, SIRT1 and AMPK, an energy sensing network that controls energy expenditure

(2009) Carles Cantó et al.   CURRENT OPINION IN LIPIDOLOGY

Universal sample preparation method for proteome analysis

(2009) Jacek R Wiśniewski et al.   NATURE METHODS