A novel viral vaccine platform based on engineered transfer RNA

Generation of Premature Termination Codon (PTC)-Harboring Pseudorabies Virus (PRV) via Genetic Code Expansion Technology

(2022) Tong-Yun Wang et al.   Viruses-Basel

Neuropilin-1 Facilitates Pseudorabies Virus Replication and Viral Glycoprotein B Promotes Its Degradation in a Furin-Dependent Manner

(2022) Meng Chen et al.   JOURNAL OF VIROLOGY

Evaluating angiotensin-converting enzyme 2-mediated SARS-CoV-2 entry across species

(2021) Hong-Liang Zhang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Vaccine development for emerging infectious diseases

(2021) Jean-Louis Excler et al.   NATURE MEDICINE

A pneumonia outbreak associated with a new coronavirus of probable bat origin

(2020) Peng Zhou et al.   NATURE

Trypsin promotes porcine deltacoronavirus mediating cell-to-cell fusion in a cell type-dependent manner

(2020) Yue-Lin Yang et al.   Emerging Microbes & Infections

Isobavachalcone inhibits Pseudorabies virus by impairing virus-induced cell-to-cell fusion

(2020) Yu Wang et al.   Virology Journal

Construction and characterization of UAA-controlled recombinant Zika virus by genetic code expansion

(2020) Rong-Rong Zhang et al.   Science China-Life Sciences

Engineered transfer RNAs for suppression of premature termination codons

(2019) John D. Lueck et al.   Nature Communications

Construction of an infectious bacterial artificial chromosome clone of a pseudorabies virus variant: Reconstituted virus exhibited wild-type properties in vitro and in vivo

(2018) Tao Wang et al.   JOURNAL OF VIROLOGICAL METHODS

mRNA vaccines — a new era in vaccinology

(2018) Norbert Pardi et al.   NATURE REVIEWS DRUG DISCOVERY

Functional Relevance of the N-Terminal Domain of Pseudorabies Virus Envelope Glycoprotein H and Its Interaction with Glycoprotein L

(2017) Melina Vallbracht et al.   JOURNAL OF VIROLOGY

Expanding and reprogramming the genetic code

(2017) Jason W. Chin   NATURE

Controlling Multicycle Replication of Live-Attenuated HIV-1 Using an Unnatural Genetic Switch

(2017) Zhe Yuan et al.   ACS Synthetic Biology

Zika Virus

(2016) Lyle R. Petersen et al.   NEW ENGLAND JOURNAL OF MEDICINE

Generation of influenza A viruses as live but replication-incompetent virus vaccines

(2016) L. Si et al.   SCIENCE

The structure and flexibility of conical HIV-1 capsids determined within intact virions

(2016) Simone Mattei et al.   SCIENCE

CRISPRi-Manipulation of Genetic Code Expansion via RF1 for Reassignment of Amber Codon in Bacteria

(2016) Bo Zhang et al.   Scientific Reports

Construction of a Live-Attenuated HIV-1 Vaccine through Genetic Code Expansion

(2014) Nanxi Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expanding and Reprogramming the Genetic Code of Cells and Animals

(2014) Jason W. Chin   Annual Review of Biochemistry

Efficient Multisite Unnatural Amino Acid Incorporation in Mammalian Cells via Optimized Pyrrolysyl tRNA Synthetase/tRNA Expression and Engineered eRF1

(2014) Wolfgang H. Schmied et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Equine Viperin Restricts Equine Infectious Anemia Virus Replication by Inhibiting the Production and/or Release of Viral Gag, Env, and Receptor via Distortion of the Endoplasmic Reticulum

(2014) Y.-D. Tang et al.   JOURNAL OF VIROLOGY

Emergence of Zaire Ebola Virus Disease in Guinea

(2014) Sylvain Baize et al.   NEW ENGLAND JOURNAL OF MEDICINE

Site-Specific Engineering of Chemical Functionalities on the Surface of Live Hepatitis D Virus

(2013) Shixian Lin et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

A Versatile Platform for Single- and Multiple-Unnatural Amino Acid Mutagenesis in Escherichia coli

(2013) Abhishek Chatterjee et al.   BIOCHEMISTRY

Isolation of a Novel Coronavirus from a Man with Pneumonia in Saudi Arabia

(2012) Ali M. Zaki et al.   NEW ENGLAND JOURNAL OF MEDICINE

Rationalizing the development of live attenuated virus vaccines

(2010) Adam S Lauring et al.   NATURE BIOTECHNOLOGY

An Enhanced System for Unnatural Amino Acid Mutagenesis in E. coli

(2009) Travis S. Young et al.   JOURNAL OF MOLECULAR BIOLOGY