Activation of new replication foci under conditions of replication stress

DNA replication stress as an Achilles’ heel of cancer

(2015) Caterina Da-Rè et al.   Oncotarget

Allyl isothiocyanate induces replication-associated DNA damage response in NSCLC cells and sensitizes to ionizing radiation

(2015) Kaushlendra Tripathi et al.   Oncotarget

Activation of DNA Damage Response Signaling by Condensed Chromatin

(2014) Rebecca C. Burgess et al.   Cell Reports

Location, location, location: it's all in the timing for replication origins

(2013) O. M. Aparicio   GENES & DEVELOPMENT

Controlling DNA replication origins in response to DNA damage - inhibit globally, activate locally

(2013) M. Yekezare et al.   JOURNAL OF CELL SCIENCE

Spatial organization of RNA polymerase II inside a mammalian cell nucleus revealed by reflected light-sheet superresolution microscopy

(2013) Z. W. Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A heterochromatin protein 1 (HP1) dimer and a proliferating cell nuclear antigen (PCNA) protein interact in vivo and are parts of a multiprotein complex involved in DNA replication and DNA repair

(2012) Dominika O. Trembecka-Lucas et al.   CELL CYCLE

Cytometric detection of chromatin relaxation, an early reporter of DNA damage response

(2011) H. Dorota Halicka et al.   CELL CYCLE

Evidence for Sequential and Increasing Activation of Replication Origins along Replication Timing Gradients in the Human Genome

(2011) Guillaume Guilbaud et al.   PLoS Computational Biology

Clusters, factories and domains

(2010) Peter J. Gillespie et al.   CELL CYCLE

DNA Topoisomerases and Their Poisoning by Anticancer and Antibacterial Drugs

(2010) Yves Pommier et al.   CHEMISTRY & BIOLOGY

Programming DNA replication origins and chromosome organization

(2010) Christelle Cayrou et al.   CHROMOSOME RESEARCH

Chk1 inhibits replication factory activation but allows dormant origin firing in existing factories

(2010) Xin Quan Ge et al.   JOURNAL OF CELL BIOLOGY

Hydroxyurea-Stalled Replication Forks Become Progressively Inactivated and Require Two Different RAD51-Mediated Pathways for Restart and Repair

(2010) Eva Petermann et al.   MOLECULAR CELL

Chk1 promotes replication fork progression by controlling replication initiation

(2010) E. Petermann et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Organization of DNA Replication

(2010) V. O. Chagin et al.   Cold Spring Harbor Perspectives in Biology

Analysis of replication factories in human cells by super-resolution light microscopy

(2009) Zoltan Cseresnyes et al.   BMC CELL BIOLOGY

Replication fork movement sets chromatin loop size and origin choice in mammalian cells

(2008) Sylvain Courbet et al.   NATURE