Protein-like structure and activity in synthetic polymers

Folding of ortho-Phenylenes

(2016) C. Scott Hartley   ACCOUNTS OF CHEMICAL RESEARCH

Hierarchical Self-Assembly for Nanomedicine

(2016) Kyle J. M. Bishop   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Triazine-Based Sequence-Defined Polymers with Side-Chain Diversity and Backbone-Backbone Interaction Motifs

(2016) Jay W. Grate et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Dynamic foldamer chemistry

(2016) Bryden A. F. Le Bailly et al.   CHEMICAL COMMUNICATIONS

Porphyrin-Cored Polymer Nanoparticles: Macromolecular Models for Heme Iron Coordination

(2016) Kyle J. Rodriguez et al.   INORGANIC CHEMISTRY

Recent progress on cyclic polymers: Synthesis, bioproperties, and biomedical applications

(2016) Xiao-Yan Tu et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Design of Synthetic Polymer Nanoparticles That Facilitate Resolubilization and Refolding of Aggregated Positively Charged Lysozyme

(2016) Masahiko Nakamoto et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Morphology and Proton Transport in Humidified Phosphonated Peptoid Block Copolymers

(2016) Jing Sun et al.   MACROMOLECULES

Precision Self-Assembly of Amphiphilic Random Copolymers into Uniform and Self-Sorting Nanocompartments in Water

(2016) Yuji Hirai et al.   MACROMOLECULES

Block-Sequence-Specific Polypeptides from α-Amino Acid N-Carboxyanhydrides: Synthesis and Influence on Polypeptide Properties

(2016) Cristina Lavilla et al.   MACROMOLECULES

Multimode Self-Folding Polymers via Reversible and Thermoresponsive Self-Assembly of Amphiphilic/Fluorous Random Copolymers

(2016) Yuta Koda et al.   MACROMOLECULES

A Critical Appraisal of RAFT-Mediated Polymerization-Induced Self-Assembly

(2016) Sarah L. Canning et al.   MACROMOLECULES

Sequence-defined bioactive macrocycles via an acid-catalysed cascade reaction

(2016) Mintu Porel et al.   Nature Chemistry

Surface water retardation around single-chain polymeric nanoparticles: critical for catalytic function?

(2016) Patrick J. M. Stals et al.   Chemical Science

A strategy for sequence control in vinyl polymers via iterative controlled radical cyclization

(2016) Yusuke Hibi et al.   Nature Communications

From precision polymers to complex materials and systems

(2016) Jean-François Lutz et al.   Nature Reviews Materials

A Scalable and High-Yield Strategy for the Synthesis of Sequence-Defined Macromolecules

(2015) Susanne C. Solleder et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Amino Acid-Functionalized Dendritic Polyglycerol for Safe and Effective siRNA Delivery

(2015) Hanxiang Zeng et al.   BIOMACROMOLECULES

Development of Guanidinium-Rich Protein Mimics for Efficient siRNA Delivery into Human T Cells

(2015) Brittany M. deRonde et al.   BIOMACROMOLECULES

Facile synthesis of nucleic acid–polymer amphiphiles and their self-assembly

(2015) Fei Jia et al.   CHEMICAL COMMUNICATIONS

Modelling of reversible single chain polymer self-assembly: from the polymer towards the protein limit

(2015) Denis Danilov et al.   CHEMICAL COMMUNICATIONS

Advances in single chain technology

(2015) Marina Gonzalez-Burgos et al.   CHEMICAL SOCIETY REVIEWS

Preparation of Information-Containing Macromolecules by Ligation of Dyad-Encoded Oligomers

(2015) Thanh Tam Trinh et al.   CHEMISTRY-A EUROPEAN JOURNAL

Triggering Activity of Catalytic Rod-Like Supramolecular Polymers

(2015) Elisa Huerta  et al.   CHEMISTRY-A EUROPEAN JOURNAL

Light-Triggered, Self-Immolative Nucleic Acid-Drug Nanostructures

(2015) Xuyu Tan et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Modular Synthetic Platform for the Construction of Functional Single-Chain Polymeric Nanoparticles: From Aqueous Catalysis to Photosensitization

(2015) Yiliu Liu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Providing Oligonucleotides with Steric Selectivity by Brush-Polymer-Assisted Compaction

(2015) Xueguang Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A General Approach to Sequence-Controlled Polymers Using Macrocyclic Ring Opening Metathesis Polymerization

(2015) Will R. Gutekunst et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Zipping Polymers into Nanoparticles via Intrachain Alternating Radical Copolymerization

(2015) Christopher K. Lyon et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Synthesis of Monodisperse Sequence-Defined Polymers Using Protecting-Group-Free Iterative Strategies

(2015) Thanh Tam Trinh et al.   MACROMOLECULAR CHEMISTRY AND PHYSICS

Single-Chain Folding of Synthetic Polymers: A Critical Update

(2015) Ozcan Altintas et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Design and Synthesis of Triblock Copolymers for Creating Complex Secondary Structures by Orthogonal Self-Assembly

(2015) Ozcan Altintas et al.   MACROMOLECULES

What Is Next in Single-Chain Nanoparticles?

(2015) Ashley M. Hanlon et al.   MACROMOLECULES

Self-assembly concepts for multicompartment nanostructures

(2015) André H. Gröschel et al.   Nanoscale

Peptoid nanosheets exhibit a new secondary-structure motif

(2015) Ranjan V. Mannige et al.   NATURE

Iterative design of a helically folded aromatic oligoamide sequence for the selective encapsulation of fructose

(2015) Nagula Chandramouli et al.   Nature Chemistry

Single-chain polymer nanoparticles: Mimic the proteins

(2015) Meng Huo et al.   POLYMER

Pd-complex driven formation of single-chain nanoparticles

(2015) Johannes Willenbacher et al.   Polymer Chemistry

A brief user's guide to single-chain nanoparticles

(2015) Christopher K. Lyon et al.   Polymer Chemistry

Toward a tunable synthetic [FeFe] hydrogenase mimic: single-chain nanoparticles functionalized with a single diiron cluster

(2015) C. A. Tooley et al.   Polymer Chemistry

Controlling monomer-sequence using supramolecular templates

(2015) Niels ten Brummelhuis   Polymer Chemistry

Scalable synthesis of sequence-defined, unimolecular macromolecules by Flow-IEG

(2015) Frank A. Leibfarth et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Simulation guided design of globular single-chain nanoparticles by tuning the solvent quality

(2015) Federica Lo Verso et al.   Soft Matter

Self-assembly of “patchy” nanoparticles: a versatile approach to functional hierarchical materials

(2015) David J. Lunn et al.   Chemical Science

Exclusive One-Way Cycle Sequence Control in Cationic Terpolymerization of General-Purpose Monomers via Concurrent Vinyl-Addition, Ring-Opening, and Carbonyl-Addition Mechanisms

(2015) Arihiro Kanazawa et al.   ACS Macro Letters

Single Chain Polymeric Nanoparticles as Selective Hydrophobic Reaction Spaces in Water

(2015) Müge Artar et al.   ACS Macro Letters

Sequence-Controlled Copolymers Prepared via Entropy-Driven Ring-Opening Metathesis Polymerization

(2015) Ryan M. Weiss et al.   ACS Macro Letters

Design of multi-functional linear polymers that capture and neutralize a toxic peptide: a comparison with cross-linked nanoparticles

(2015) Yusuke Wada et al.   Journal of Materials Chemistry B

Engineering Orthogonality in Supramolecular Polymers: From Simple Scaffolds to Complex Materials

(2014) Elizabeth Elacqua et al.   ACCOUNTS OF CHEMICAL RESEARCH

Heme Enzyme Structure and Function

(2014) Thomas L. Poulos   CHEMICAL REVIEWS

Peptidomimetics via modifications of amino acids and peptide bonds

(2014) Ilker Avan et al.   CHEMICAL SOCIETY REVIEWS

Compartmentalization of Single Polymer Chains by Stepwise Intramolecular Cross-Linking of Sequence-Controlled Macromolecules

(2014) Raj Kumar Roy et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Polycondensation of Polymer Brushes via DNA Hybridization

(2014) Xueguang Lu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Protein backbone engineering as a strategy to advance foldamers toward the frontier of protein-like tertiary structure

(2014) Zachary E. Reinert et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Artificial enzyme with magnetic properties and peroxidase activity on indoleamine metabolite tumor marker

(2014) Daniel Antuña-Jiménez et al.   POLYMER

Controlled self-assembly of amphiphilic monotailed single-chain nanoparticles

(2014) Jianguo Wen et al.   Polymer Chemistry

Enzymatic turnover of macromolecules generates long-lasting protein–water-coupled motions beyond reaction steady state

(2014) Jessica Dielmann-Gessner et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Precision polymers: a kinetic approach for functional poly(norbornenes)

(2014) Dafni Moatsou et al.   Chemical Science

Metallo-Folded Single-Chain Nanoparticles with Catalytic Selectivity

(2014) Ana Sanchez-Sanchez et al.   ACS Macro Letters

Solvent environments significantly affect the enzymatic function of Escherichia coli dihydrofolate reductase: Comparison of wild-type protein and active-site mutant D27E

(2013) Eiji Ohmae et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Supramolecular catalysis. Part 2: artificial enzyme mimics

(2013) Matthieu Raynal et al.   CHEMICAL SOCIETY REVIEWS

Understanding the catalytic activity of single-chain polymeric nanoparticles in water

(2013) Müge Artar et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Patchy Particle Self-Assembly via Metal Coordination

(2013) Yufeng Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Tandem Ring-Opening/Ring-Closing Metathesis Polymerization: Relationship between Monomer Structure and Reactivity

(2013) Hyeon Park et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single-Chain Self-Folding of Synthetic Polymers Induced by Metal-Ligand Complexation

(2013) Johannes Willenbacher et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Advantages of Orthogonal Folding of Single Polymer Chains to Soft Nanoparticles

(2013) Angel J. Moreno et al.   MACROMOLECULES

The balance between intramolecular hydrogen bonding, polymer solubility and rigidity in single-chain polymeric nanoparticles

(2013) Patrick J. M. Stals et al.   Polymer Chemistry

Sequence-Controlled Polymers

(2013) J.-F. Lutz et al.   SCIENCE

Endowing Single-Chain Polymer Nanoparticles with Enzyme-Mimetic Activity

(2013) Irma Perez-Baena et al.   ACS Macro Letters

Self-Assembly of Monotethered Single-Chain Nanoparticle Shape Amphiphiles

(2013) Jianguo Wen et al.   ACS Macro Letters

“Michael” Nanocarriers Mimicking Transient-Binding Disordered Proteins

(2013) Ana Sanchez-Sanchez et al.   ACS Macro Letters

Consequences of Folding a Water-Soluble Polymer Around an Organocatalyst

(2012) Elisa Huerta et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Palladium-Catalyzed Cross-Coupling: A Historical Contextual Perspective to the 2010 Nobel Prize

(2012) Carin C. C. Johansson Seechurn et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Orthogonal Self-Assembly in Folding Block Copolymers

(2012) Nobuhiko Hosono et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Engineered Synthetic Polymer Nanoparticles as IgG Affinity Ligands

(2012) Shih-Hui Lee et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Single Chain Folding of Synthetic Polymers by Covalent and Non-Covalent Interactions: Current Status and Future Perspectives

(2012) Ozcan Altintas et al.   MACROMOLECULAR RAPID COMMUNICATIONS

Synthesis and characterization of hydrogenated poly(norbornene endo-dicarboximide)s prepared by ring opening metathesis polymerization

(2012) Kyung-Hwan Yoon et al.   POLYMER

Single chain polymeric nanoparticles as compartmentalised sensors for metal ions

(2012) Martijn A. J. Gillissen et al.   Polymer Chemistry

Single-Chain Polymeric Nanoparticles by Stepwise Folding

(2011) Tristan Mes et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Single chain self-assembly of well-defined heterotelechelic polymers generated by ATRP and click chemistry revisited

(2011) Ozcan Altintas et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Single-Chain Folding of Polymers for Catalytic Systems in Water

(2011) Takaya Terashima et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Controlled folding of synthetic polymer chains through the formation of positionable covalent bridges

(2011) Bernhard V. K. J. Schmidt et al.   Nature Chemistry

Single-chain technology using discrete synthetic macromolecules

(2011) Makoto Ouchi et al.   Nature Chemistry

Correlated structural kinetics and retarded solvent dynamics at the metalloprotease active site

(2011) Moran Grossman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Bioinspired dual self-folding of single polymer chains via reversible hydrogen bonding

(2011) Ozcan Altintas et al.   Polymer Chemistry

Mechanism of the hydrophobic effect in the biomolecular recognition of arylsulfonamides by carbonic anhydrase

(2011) P. W. Snyder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The rational design of a synthetic polymer nanoparticle that neutralizes a toxic peptide in vivo

(2011) Y. Hoshino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Single chain self-assembly: preparation of α,ω-donor–acceptor chains via living radical polymerization and orthogonal conjugation

(2010) Ozcan Altintas et al.   CHEMICAL COMMUNICATIONS

Mimicking nitrogenase

(2010) Ian Dance   DALTON TRANSACTIONS

Tuning the size of supramolecular single-chain polymer nanoparticles

(2010) E. Johan Foster et al.   JOURNAL OF POLYMER SCIENCE PART A-POLYMER CHEMISTRY

Toward Controlling Folding in Synthetic Polymers: Fabricating and Characterizing Supramolecular Single-Chain Nanoparticles

(2010) Erik B. Berda et al.   MACROMOLECULES

Sequence control in polymer synthesis

(2009) Nezha Badi et al.   CHEMICAL SOCIETY REVIEWS

Metastable Supramolecular Polymer Nanoparticles via Intramolecular Collapse of Single Polymer Chains

(2009) E. Johan Foster et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY