Characterization of a Family of Scorpion Toxins Modulating Ca2+-Activated Cl− Current in Vascular Myocytes

Conditional deletion of TMEM16A in cholinergic neurons of the medial habenula induces anhedonic-like behavior in mice

(2022) Jae Gwang Song et al.   BEHAVIOURAL BRAIN RESEARCH

ColabFold: making protein folding accessible to all

(2022) Milot Mirdita et al.   NATURE METHODS

A small molecule inhibitor of the chloride channel TMEM16A blocks vascular smooth muscle contraction and lowers blood pressure in spontaneously hypertensive rats

(2021) Onur Cil et al.   KIDNEY INTERNATIONAL

TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner

(2021) Huaqing Zheng et al.   Acta Pharmaceutica Sinica B

An outer-pore gate modulates the pharmacology of the TMEM16A channel

(2021) Ria L. Dinsdale et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cell Death Induction and Protection by Activation of Ubiquitously Expressed Anion/Cation Channels. Part 2: Functional and Molecular Properties of ASOR/PAC Channels and Their Roles in Cell Volume Dysregulation and Acidotoxic Cell Death

(2021) Yasunobu Okada et al.   Frontiers in Cell and Developmental Biology

Cepharanthine, a novel selective ANO1 inhibitor with potential for lung adenocarcinoma therapy

(2021) Xuan Zhang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl ‐ concentration

(2021) Xiao‐Long Li et al.   BRITISH JOURNAL OF PHARMACOLOGY

Calcium-Activated Chloride Channels in Myometrial and Vascular Smooth Muscle

(2021) Susan Wray et al.   Frontiers in Physiology

TMEM16A/ANO1: Current Strategies and Novel Drug Approaches for Cystic Fibrosis

(2021) Christie Mitri et al.   Cells

Chlorotoxin-directed CAR T cells for specific and effective targeting of glioblastoma

(2020) Dongrui Wang et al.   Science Translational Medicine

Ca2+-activated Cl− channel TMEM16A inhibition by cholesterol promotes angiogenesis in endothelial cells

(2020) Ke Ma et al.   Journal of Advanced Research

The Ion Channel and GPCR Toolkit of Brain Capillary Pericytes

(2020) Ashwini Hariharan et al.   Frontiers in Cellular Neuroscience

The Ca2+-activated chloride channel ANO1/TMEM16A: An emerging therapeutic target for epithelium-originated diseases?

(2020) Yani Liu et al.   Acta Pharmaceutica Sinica B

Effects of Selective Substitution of Cysteine Residues on the Conformational Properties of Chlorotoxin Explored by Molecular Dynamics Simulations

(2019) Andrew Gregory et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Phase 1 Safety, Pharmacokinetics, and Fluorescence Imaging Study of Tozuleristide (BLZ-100) in Adults With Newly Diagnosed or Recurrent Gliomas

(2019) Chirag G Patil et al.   NEUROSURGERY

Smooth muscle-specific TMEM16A expression protects against angiotensin II-induced cerebrovascular remodeling via suppressing extracellular matrix deposition

(2019) Xue-Lin Zeng et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Recent advances in TMEM16A: Structure, function, and disease

(2018) Qiushuang Ji et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Chlorotoxin—A Multimodal Imaging Platform for Targeting Glioma Tumors

(2018) Gadi Cohen et al.   Toxins

TMEM16A Contributes to Endothelial Dysfunction by Facilitating Nox2 NADPH Oxidase–Derived Reactive Oxygen Species Generation in HypertensionNovelty and Significance

(2017) Ming-Ming Ma et al.   HYPERTENSION

Peptide toxins and small-molecule blockers of BK channels

(2016) Mu Yu et al.   ACTA PHARMACOLOGICA SINICA

Structure-Activity Relationship of Chlorotoxin-Like Peptides

(2016) Syed Ali et al.   Toxins

Regulation of vascular tone and arterial blood pressure: role of chloride transport in vascular smooth muscle

(2015) Christian A. Hübner et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion

(2015) Lucie Dardevet et al.   Toxins

Downregulation of TMEM16A Calcium-Activated Chloride Channel Contributes to Cerebrovascular Remodeling During Hypertension by Promoting Basilar Smooth Muscle Cell Proliferation

(2012) Mi Wang et al.   CIRCULATION

TMEM16A/ANO1 Channels Contribute to the Myogenic Response in Cerebral Arteries

(2012) Simon Bulley et al.   CIRCULATION RESEARCH

TMEM16A/Anoctamin 1 protein mediates calcium-activated chloride currents in pulmonary arterial smooth muscle cells

(2010) Boris Manoury et al.   JOURNAL OF PHYSIOLOGY-LONDON

Expression Cloning of TMEM16A as a Calcium-Activated Chloride Channel Subunit

(2008) Björn Christian Schroeder et al.   CELL

TMEM16A confers receptor-activated calcium-dependent chloride conductance

(2008) Young Duk Yang et al.   NATURE

TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity

(2008) A. Caputo et al.   SCIENCE