Phase 1 Safety, Pharmacokinetics, and Fluorescence Imaging Study of Tozuleristide (BLZ-100) in Adults With Newly Diagnosed or Recurrent Gliomas

Image-Guided Surgery Using Invisible Near-Infrared Light: Fundamentals of Clinical Translation

(2018) Sylvain Gioux et al.   Molecular Imaging

Nonclinical Profile of BLZ-100, a Tumor-Targeting Fluorescent Imaging Agent

(2017) Julia Parrish-Novak et al.   INTERNATIONAL JOURNAL OF TOXICOLOGY

TRTH-12. PHASE 1 SAFETY, PHARMACOKINETIC AND IMAGING STUDY OF BLZ-100 TUMOR PAINT IN PEDIATRIC BRAIN TUMOR PATIENTS

(2017) Amy Lee et al.   NEURO-ONCOLOGY

Chlorotoxin: Structure, activity, and potential uses in cancer therapy

(2016) Paola G. Ojeda et al.   BIOPOLYMERS

Technical principles in glioma surgery and preoperative considerations

(2016) Daria Krivosheya et al.   JOURNAL OF NEURO-ONCOLOGY

Intraoperative Near-Infrared Optical Imaging Can Localize Gadolinium-Enhancing Gliomas During Surgery

(2016) John Y.K. Lee et al.   NEUROSURGERY

Fluorescence Identification of Head and Neck Squamous Cell Carcinoma and High-Risk Oral Dysplasia With BLZ-100, a Chlorotoxin-Indocyanine Green Conjugate

(2016) Fred M. Baik et al.   JAMA Otolaryngology-Head & Neck Surgery

Association of the Extent of Resection With Survival in Glioblastoma

(2016) Timothy J. Brown et al.   JAMA Oncology

Image-Guided Tumor Resection

(2015) Julia Parrish-Novak et al.   CANCER JOURNAL

Preclinical Validation of the Utility of BLZ-100 in Providing Fluorescence Contrast for Imaging Spontaneous Solid Tumors

(2015) J. Fidel et al.   CANCER RESEARCH

Clinical benefit from resection of recurrent glioblastomas: results of a multicenter study including 503 patients with recurrent glioblastomas undergoing surgical resection

(2015) Florian Ringel et al.   NEURO-ONCOLOGY

Intraoperative brain cancer detection with Raman spectroscopy in humans

(2015) Michael Jermyn et al.   Science Translational Medicine

Chlorotoxin: A Helpful Natural Scorpion Peptide to Diagnose Glioma and Fight Tumor Invasion

(2015) Lucie Dardevet et al.   Toxins

Near-infrared imaging of brain tumors using the Tumor Paint BLZ-100 to achieve near-complete resection of brain tumors

(2014) Pramod V. Butte et al.   Neurosurgical Focus

Characterization of IRDye 800CW chlorotoxin as a targeting agent for brain tumors

(2013) Joy L. Kovar et al.   ANALYTICAL BIOCHEMISTRY

Risk factors and outcomes associated with surgical site infections after craniotomy or craniectomy

(2013) Hsiu-Yin Chiang et al.   JOURNAL OF NEUROSURGERY

In Vivo Bio-imaging Using Chlorotoxin-based Conjugates

(2012) Mark R. Stroud et al.   CURRENT PHARMACEUTICAL DESIGN

An Experimental Study to Evaluate the Fluobeam 800 Imaging System for Fluorescence-Guided Lymphatic Imaging and Sentinel Node Biopsy

(2012) Christoph Hirche et al.   Surgical Innovation

Annexin A2 Is a Molecular Target for TM601, a Peptide with Tumor-targeting and Anti-angiogenic Effects

(2009) Kamala Kesavan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Extent of Resection in the Long-Term Outcome of Low-Grade Hemispheric Gliomas

(2008) Justin S. Smith et al.   JOURNAL OF CLINICAL ONCOLOGY

Effective transvascular delivery of nanoparticles across the blood-brain tumor barrier into malignant glioma cells

(2008) Hemant Sarin et al.   Journal of Translational Medicine