Nuclear-cytoplasmic compartmentalization of cyclin B1-Cdk1 promotes robust timing of mitotic events

In vitro cell cycle oscillations exhibit a robust and hysteretic response to changes in cytoplasmic density

(2022) Minjun Jin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chk1 dynamics in G2 phase upon replication stress predict daughter cell outcome

(2022) Vicente Lebrec et al.   DEVELOPMENTAL CELL

The Hydrophobic Patch Directs Cyclin B to Centrosomes to Promote Global CDK Phosphorylation at Mitosis

(2020) Souradeep Basu et al.   CURRENT BIOLOGY

Nuclei determine the spatial origin of mitotic waves

(2020) Felix Eduard Nolet et al.   eLife

The nucleus serves as the pacemaker for the cell cycle

(2020) Oshri Afanzar et al.   eLife

Temperature-Induced uncoupling of cell cycle regulators

(2020) Hanieh Falahati et al.   DEVELOPMENTAL BIOLOGY

Aneuploidy in Oocytes Is Prevented by Sustained CDK1 Activity through Degron Masking in Cyclin B1

(2019) Mark D. Levasseur et al.   DEVELOPMENTAL CELL

Self-Organized Nuclear Positioning Synchronizes the Cell Cycle in Drosophila Embryos

(2019) Victoria E. Deneke et al.   CELL

Building Dynamic Cellular Machineries in Droplet-Based Artificial Cells with Single-Droplet Tracking and Analysis

(2019) Meng Sun et al.   ANALYTICAL CHEMISTRY

A robust and tunable mitotic oscillator in artificial cells

(2018) Ye Guan et al.   eLife

Incoherent Inputs Enhance the Robustness of Biological Oscillators

(2017) Zhengda Li et al.   Cell Systems

CDK Substrate Phosphorylation and Ordering the Cell Cycle

(2016) Matthew P. Swaffer et al.   CELL

Waves of Cdk1 Activity in S Phase Synchronize the Cell Cycle in Drosophila Embryos

(2016) Victoria E. Deneke et al.   DEVELOPMENTAL CELL

Positive Feedback Keeps Duration of Mitosis Temporally Insulated from Upstream Cell-Cycle Events

(2016) Ana Rita Araujo et al.   MOLECULAR CELL

The free-energy cost of accurate biochemical oscillations

(2015) Yuansheng Cao et al.   Nature Physics

From Egg to Gastrula: How the Cell Cycle Is Remodeled During the Drosophila Mid-Blastula Transition

(2014) Jeffrey A. Farrell et al.   Annual Review of Genetics

Diversity in the dynamical behaviour of a compartmentalized programmable biochemical oscillator

(2014) Maximilian Weitz et al.   Nature Chemistry

Optimization of a genetically encoded biosensor for cyclin B1-cyclin dependent kinase 1

(2013) Ahmed Saied F. Belal et al.   Molecular BioSystems

Stochastic ERK Activation Induced by Noise and Cell-to-Cell Propagation Regulates Cell Density-Dependent Proliferation

(2013) Kazuhiro Aoki et al.   MOLECULAR CELL

The Cdk1–APC/C cell cycle oscillator circuit functions as a time-delayed, ultrasensitive switch

(2013) Qiong Yang et al.   NATURE CELL BIOLOGY

Spatial Positive Feedback at the Onset of Mitosis

(2012) Silvia D.M. Santos et al.   CELL

Frequency-Modulated Pulses of ERK Activity Transmit Quantitative Proliferation Signals

(2012) John G. Albeck et al.   MOLECULAR CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Modeling the Cell Cycle: Why Do Certain Circuits Oscillate?

(2011) James E. Ferrell et al.   CELL

Development of an optimized backbone of FRET biosensors for kinases and GTPases

(2011) Naoki Komatsu et al.   MOLECULAR BIOLOGY OF THE CELL

Ultrasensitivity in the Regulation of Cdc25C by Cdk1

(2011) Nicole B. Trunnell et al.   MOLECULAR CELL

Progressive Activation of CyclinB1-Cdk1 Coordinates Entry to Mitosis

(2010) Olivier Gavet et al.   DEVELOPMENTAL CELL

Cyclin B–Cdk1 activates its own pump to get into the nucleus

(2010) Arne Lindqvist   JOURNAL OF CELL BIOLOGY

Activation of cyclin B1–Cdk1 synchronizes events in the nucleus and the cytoplasm at mitosis

(2010) Olivier Gavet et al.   JOURNAL OF CELL BIOLOGY

Distinct Pools of cdc25C Are Phosphorylated on Specific TP Sites and Differentially Localized in Human Mitotic Cells

(2010) Celine Franckhauser et al.   PLoS One

Differential phosphorylation of Cdc25C phosphatase in mitosis

(2008) Jérôme Bonnet et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cyclin B1 is localized to unattached kinetochores and contributes to efficient microtubule attachment and proper chromosome alignment during mitosis

(2008) Qiang Chen et al.   CELL RESEARCH

A genetically encoded fluorescent sensor of ERK activity

(2008) C. D. Harvey et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Robust, Tunable Biological Oscillations from Interlinked Positive and Negative Feedback Loops

(2008) T. Y.-C. Tsai et al.   SCIENCE