Molecular and cellular neurocardiology: development, and cellular and molecular adaptations to heart disease

Myocardial Infarction Causes Transient Cholinergic Transdifferentiation of Cardiac Sympathetic Nerves via gp130

(2016) A. Olivas et al.   JOURNAL OF NEUROSCIENCE

Protection against ventricular fibrillation via cholinergic receptor stimulation and the generation of nitric oxide

(2016) Manish Kalla et al.   JOURNAL OF PHYSIOLOGY-LONDON

Neurotransmission to parasympathetic cardiac vagal neurons in the brain stem is altered with left ventricular hypertrophy-induced heart failure

(2015) Edmund Cauley et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiac Resynchronization Therapy Restores Sympathovagal Balance in the Failing Heart by Differential Remodeling of Cholinergic Signaling

(2015) D. DeMazumder et al.   CIRCULATION RESEARCH

Cardiac Innervation and Sudden Cardiac Death

(2015) K. Fukuda et al.   CIRCULATION RESEARCH

Arrhythmogenic Remodeling of  2 Versus  1 Adrenergic Signaling in the Human Failing Heart

(2015) D. Lang et al.   Circulation-Arrhythmia and Electrophysiology

Nerves Regulate Cardiomyocyte Proliferation and Heart Regeneration

(2015) Ahmed I. Mahmoud et al.   DEVELOPMENTAL CELL

Control of ventricular excitability by neurons of the dorsal motor nucleus of the vagus nerve

(2015) Asif Machhada et al.   HEART RHYTHM

CAPON Modulates Neuronal Calcium Handling and Cardiac Sympathetic Neurotransmission During Dysautonomia in HypertensionNovelty and Significance

(2015) Chieh-Ju Lu et al.   HYPERTENSION

Efficacy of B-Type Natriuretic Peptide Is Coupled to Phosphodiesterase 2A in Cardiac Sympathetic NeuronsNovelty and Significance

(2015) Dan Li et al.   HYPERTENSION

S-Nitrosylation Induces Both Autonomous Activation and Inhibition of Calcium/Calmodulin-dependent Protein Kinase II δ

(2015) Jeffrey R. Erickson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A systematic analysis of neonatal mouse heart regeneration after apical resection

(2015) Donald Marion Bryant et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

CaMKIIδ mediates β-adrenergic effects on RyR2 phosphorylation and SR Ca2+ leak and the pathophysiological response to chronic β-adrenergic stimulation

(2015) Michael Grimm et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Innervating sympathetic neurons regulate heart size and the timing of cardiomyocyte cell cycle withdrawal

(2015) R. E. Kreipke et al.   JOURNAL OF PHYSIOLOGY-LONDON

Optogenetics for in vivo cardiac pacing and resynchronization therapies

(2015) Udi Nussinovitch et al.   NATURE BIOTECHNOLOGY

Optogenetic determination of the myocardial requirements for extrasystoles by cell type-specific targeting of ChannelRhodopsin-2

(2015) Tania Zaglia et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Targeting protein tyrosine phosphatase σ after myocardial infarction restores cardiac sympathetic innervation and prevents arrhythmias

(2015) R. T. Gardner et al.   Nature Communications

RETRACTED: Oxidative Stress and Ca 2+ Release Events in Mouse Cardiomyocytes

(2014) Natalia Shirokova et al.   BIOPHYSICAL JOURNAL

Optogenetic release of norepinephrine from cardiac sympathetic neurons alters mechanical and electrical function

(2014) Anastasia M. Wengrowski et al.   CARDIOVASCULAR RESEARCH

Role of the Autonomic Nervous System in Modulating Cardiac Arrhythmias

(2014) Mark J. Shen et al.   CIRCULATION RESEARCH

Autonomic control of the heart: going beyond the classical neurotransmitters

(2014) Neil Herring   EXPERIMENTAL PHYSIOLOGY

Vagus nerve stimulation initiated late during ischemia, but not reperfusion, exerts cardioprotection via amelioration of cardiac mitochondrial dysfunction

(2014) Krekwit Shinlapawittayatorn et al.   HEART RHYTHM

Optogenetic Stimulation of Locus Ceruleus Neurons Augments Inhibitory Transmission to Parasympathetic Cardiac Vagal Neurons via Activation of Brainstem  1 and  1 Receptors

(2014) X. Wang et al.   JOURNAL OF NEUROSCIENCE

Maximal acceleration of Ca2+release refractoriness by β-adrenergic stimulation requires dual activation of kinases PKA and CaMKII in mouse ventricular myocytes

(2014) Eva Poláková et al.   JOURNAL OF PHYSIOLOGY-LONDON

Decreased inward rectifying K+current and increased ryanodine receptor sensitivity synergistically contribute to sustained focal arrhythmia in the intact rabbit heart

(2014) Rachel C. Myles et al.   JOURNAL OF PHYSIOLOGY-LONDON

Cardiac sympathetic denervation to prevent life-threatening arrhythmias

(2014) Peter J. Schwartz   Nature Reviews Cardiology

Nitric Oxide-Dependent Activation of CaMKII Increases Diastolic Sarcoplasmic Reticulum Calcium Release in Cardiac Myocytes in Response to Adrenergic Stimulation

(2014) Jerry Curran et al.   PLoS One

Cardiac applications of optogenetics

(2014) Christina M. Ambrosi et al.   PROGRESS IN BIOPHYSICS & MOLECULAR BIOLOGY

3D multifunctional integumentary membranes for spatiotemporal cardiac measurements and stimulation across the entire epicardium

(2014) Lizhi Xu et al.   Nature Communications

Focal myocardial infarction induces global remodeling of cardiac sympathetic innervation: neural remodeling in a spatial context

(2013) Olujimi A. Ajijola et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiac sympathetic dysfunction in the prehypertensive spontaneously hypertensive rat

(2013) Julia Shanks et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Peripheral cardiac sympathetic hyperactivity in cardiovascular disease: role of neuropeptides

(2013) Julia Shanks et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

NO-dependent CaMKII activation during β-adrenergic stimulation of cardiac muscle

(2013) Daniel A. Gutierrez et al.   CARDIOVASCULAR RESEARCH

Nerves projecting from the intrinsic cardiac ganglia of the pulmonary veins modulate sinoatrial node pacemaker function

(2013) Manuel Zarzoso et al.   CARDIOVASCULAR RESEARCH

Oxidized Ca 2+ /Calmodulin-Dependent Protein Kinase II Triggers Atrial Fibrillation

(2013) Anil Purohit et al.   CIRCULATION

Relationship of plasma neuropeptide Y with angiographic, electrocardiographic and coronary physiology indices of reperfusion during ST elevation myocardial infarction

(2013) Florim Cuculi et al.   HEART

Cardiac sympathetic denervation in patients with refractory ventricular arrhythmias or electrical storm: Intermediate and long-term follow-up

(2013) Marmar Vaseghi et al.   HEART RHYTHM

Infarct-Derived Chondroitin Sulfate Proteoglycans Prevent Sympathetic Reinnervation after Cardiac Ischemia-Reperfusion Injury

(2013) R. T. Gardner et al.   JOURNAL OF NEUROSCIENCE

In situ three-dimensional reconstruction of mouse heart sympathetic innervation by two-photon excitation fluorescence imaging

(2013) Kim Freeman et al.   JOURNAL OF NEUROSCIENCE METHODS

Myths and realities of the cardiac vagus

(2013) J. H. Coote   JOURNAL OF PHYSIOLOGY-LONDON

Regional Myocardial Sympathetic Denervation Predicts the Risk of Sudden Cardiac Arrest in Ischemic Cardiomyopathy

(2013) James A. Fallavollita et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Diabetic hyperglycaemia activates CaMKII and arrhythmias by O-linked glycosylation

(2013) Jeffrey R. Erickson et al.   NATURE

CGRP inhibits norepinephrine induced apoptosis with restoration of Bcl-2/Bax in cultured cardiomyocytes of rat

(2013) Yan-Xia Ma et al.   NEUROSCIENCE LETTERS

Alpha-calcitonin gene-related peptide is protective against pressure overload-induced heart failure

(2013) Jianping Li et al.   REGULATORY PEPTIDES

Sympathetic stimulation increases dispersion of repolarization in humans with myocardial infarction

(2012) Marmar Vaseghi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Functional differences between junctional and extrajunctional adrenergic receptor activation in mammalian ventricle

(2012) Olujimi A. Ajijola et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardioprotection evoked by remote ischaemic preconditioning is critically dependent on the activity of vagal pre-ganglionic neurones

(2012) Svetlana Mastitskaya et al.   CARDIOVASCULAR RESEARCH

New Therapeutic Targets in Cardiology

(2012) Adam G. Rokita et al.   CIRCULATION

Calmodulin-Dependent Protein Kinase II: Linking Heart Failure and Arrhythmias

(2012) Paari Dominic Swaminathan et al.   CIRCULATION RESEARCH

Local β-Adrenergic Stimulation Overcomes Source-Sink Mismatch to Generate Focal Arrhythmia

(2012) Rachel C. Myles et al.   CIRCULATION RESEARCH

Development, Maturation, and Transdifferentiation of Cardiac Sympathetic Nerves

(2012) Kensuke Kimura et al.   CIRCULATION RESEARCH

Cardiotoxic and Cardioprotective Features of Chronic β-Adrenergic Signaling

(2012) Xiaoying Zhang et al.   CIRCULATION RESEARCH

Abnormal Intracellular Calcium Homeostasis in Sympathetic Neurons From Young Prehypertensive Rats

(2012) Dan Li et al.   HYPERTENSION

Targeted Neuronal Nitric Oxide Synthase Transgene Delivery Into Stellate Neurons Reverses Impaired Intracellular Calcium Transients in Prehypertensive Rats

(2012) Dan Li et al.   HYPERTENSION

Ganglion-Specific Impairment of the Norepinephrine Transporter in the Hypertensive Rat

(2012) Julia Shanks et al.   HYPERTENSION

Nerve Sprouting Contributes to Increased Severity of Ventricular Tachyarrhythmias by Upregulating iGluRs in Rats with Healed Myocardial Necrotic Injury

(2012) Jing Lü et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Selective optogenetic stimulation of cholinergic axons in neocortex

(2012) Abigail Kalmbach et al.   JOURNAL OF NEUROPHYSIOLOGY

CaMKII determines mitochondrial stress responses in heart

(2012) Mei-ling A. Joiner et al.   NATURE

Cardiovascular autonomic neuropathies as complications of diabetes mellitus

(2012) Michael Kuehl et al.   Nature Reviews Endocrinology

Development of cardiac parasympathetic neurons, glial cells, and regional cholinergic innervation of the mouse heart

(2012) S.P. Fregoso et al.   NEUROSCIENCE

Altered atrial neurotransmitter release in transgenic p75−/− and gp130 KO mice

(2012) Wohaib Hasan et al.   NEUROSCIENCE LETTERS

Remodeling of cardiac cholinergic innervation and control of heart rate in mice with streptozotocin-induced diabetes

(2011) Abigail M. Mabe et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Substance P induces adverse myocardial remodelling via a mechanism involving cardiac mast cells

(2011) Giselle C. Meléndez et al.   CARDIOVASCULAR RESEARCH

Vagus nerve stimulation protects against ventricular fibrillation independent of muscarinic receptor activation

(2011) Kieran E. Brack et al.   CARDIOVASCULAR RESEARCH

A Mechanism for Tunable Autoinhibition in the Structure of a Human Ca2+/Calmodulin- Dependent Kinase II Holoenzyme

(2011) Luke H. Chao et al.   CELL

Oxidized CaMKII causes cardiac sinus node dysfunction in mice

(2011) Paari Dominic Swaminathan et al.   JOURNAL OF CLINICAL INVESTIGATION

The cardiac sympathetic co-transmitter galanin reduces acetylcholine release and vagal bradycardia: Implications for neural control of cardiac excitability

(2011) Neil Herring et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Oxidation of CaMKII determines the cardiotoxic effects of aldosterone

(2011) B Julie He et al.   NATURE MEDICINE

Effect of Nesiritide in Patients with Acute Decompensated Heart Failure

(2011) C.M. O'Connor et al.   NEW ENGLAND JOURNAL OF MEDICINE

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Cardiac electrical remodeling in health and disease

(2011) Michael J. Cutler et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Heterogeneous ventricular sympathetic innervation, altered β-adrenergic receptor expression, and rhythm instability in mice lacking the p75 neurotrophin receptor

(2010) Christina U. Lorentz et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Norepinephrine-induced nerve growth factor depletion causes cardiac sympathetic denervation in severe heart failure

(2010) Kensuke Kimura et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Nerve Growth Factor Promotes Cardiac Repair following Myocardial Infarction

(2010) Marco Meloni et al.   CIRCULATION RESEARCH

Heart failure causes cholinergic transdifferentiation of cardiac sympathetic nerves via gp130-signaling cytokines in rodents

(2010) Hideaki Kanazawa et al.   JOURNAL OF CLINICAL INVESTIGATION

Pravastatin normalises peripheral cardiac sympathetic hyperactivity in the spontaneously hypertensive rat

(2010) Neil Herring et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Impaired Cardiac Sympathetic Innervation and Myocardial Perfusion Are Related to Lethal Arrhythmia: Quantification of Cardiac Tracers in Patients with ICDs

(2010) K. Nishisato et al.   JOURNAL OF NUCLEAR MEDICINE

Cardiac Sympathetic Denervation Assessed With 123-Iodine Metaiodobenzylguanidine Imaging Predicts Ventricular Arrhythmias in Implantable Cardioverter-Defibrillator Patients

(2010) Mark J. Boogers et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Waterproof AlInGaP optoelectronics on stretchable substrates with applications in biomedicine and robotics

(2010) Rak-Hwan Kim et al.   NATURE MATERIALS

Characterization of Engineered Channelrhodopsin Variants with Improved Properties and Kinetics

(2009) John Y. Lin et al.   BIOPHYSICAL JOURNAL

Structural and functional cardiac cholinergic deficits in adult neurturin knockout mice

(2009) A. M. Mabe et al.   CARDIOVASCULAR RESEARCH

Genetic Variations in Nitric Oxide Synthase 1 Adaptor Protein Are Associated With Sudden Cardiac Death in US White Community-Based Populations

(2009) W.H. Linda Kao et al.   CIRCULATION

Control of cardiac contractility in the rat working heart-brainstem preparation

(2009) Eugene Nalivaiko et al.   EXPERIMENTAL PHYSIOLOGY

Infarction-induced cytokines cause local depletion of tyrosine hydroxylase in cardiac sympathetic nerves

(2009) Diana C. Parrish et al.   EXPERIMENTAL PHYSIOLOGY

Cholinoceptive and cholinergic properties of cardiomyocytes involving an amplification mechanism for vagal efferent effects in sparsely innervated ventricular myocardium

(2009) Yoshihiko Kakinuma et al.   FEBS Journal

Requirement for Ca2+/calmodulin–dependent kinase II in the transition from pressure overload–induced cardiac hypertrophy to heart failure in mice

(2009) Haiyun Ling et al.   JOURNAL OF CLINICAL INVESTIGATION

p75 and TrkA Signaling Regulates Sympathetic Neuronal Firing Patterns via Differential Modulation of Voltage-Gated Currents

(2009) J. A. Luther et al.   JOURNAL OF NEUROSCIENCE

Direct evidence of nitric oxide release from neuronal nitric oxide synthase activation in the left ventricle as a result of cervical vagus nerve stimulation

(2009) Kieran E. Brack et al.   JOURNAL OF PHYSIOLOGY-LONDON

Localization of multiple neurotransmitters in surgically derived specimens of human atrial ganglia

(2009) D.B. Hoover et al.   NEUROSCIENCE

Calmodulin kinase II is required for fight or flight sinoatrial node physiology

(2009) Y. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The   isoform of CaM kinase II is required for pathological cardiac hypertrophy and remodeling after pressure overload

(2009) J. Backs et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Membrane Fusion: Grappling with SNARE and SM Proteins

(2009) T. C. Sudhof et al.   SCIENCE

Cardiac cholinergic NO-cGMP signaling following acute myocardial infarction and nNOS gene transfer

(2008) T. A. Dawson et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Autonomic Neurotransmission: 60 Years Since Sir Henry Dale

(2008) Geoffrey Burnstock   Annual Review of Pharmacology and Toxicology

Regulation of cardiac innervation and function via the p75 neurotrophin receptor

(2008) Beth A. Habecker et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Neurochemical diversity of afferent neurons that transduce sensory signals from dog ventricular myocardium

(2008) Donald B. Hoover et al.   AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL

Chemical sympathetic denervation, suppression of myocardial transient outward potassium current, and ventricular fibrillation in the rat

(2008) Juan Bai et al.   CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY

A Dynamic Pathway for Calcium-Independent Activation of CaMKII by Methionine Oxidation

(2008) Jeffrey R. Erickson et al.   CELL

Autonomic innervation of the developing heart: Origins and function

(2008) Victoria Hildreth et al.   CLINICAL ANATOMY

Target-dependent inhibition of sympathetic neuron growth via modulation of a BMP signaling pathway

(2008) Jung-Il Moon et al.   DEVELOPMENTAL BIOLOGY

Repeated Arterial Occlusion, Delta-Opioid Receptor (DOR) Plasticity and Vagal Transmission Within the Sinoatrial Node of the Anesthetized Dog

(2008) Shekhar H. Deo et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Regulation of nerve growth factor in the heart: The role of the calcineurin–NFAT pathway

(2008) Obaida R. Rana et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Cholinergic neurons of mouse intrinsic cardiac ganglia contain noradrenergic enzymes, norepinephrine transporters, and the neurotrophin receptors tropomyosin-related kinase A and p75

(2008) J.L. Hoard et al.   NEUROSCIENCE

Deficiency of M2 muscarinic acetylcholine receptors increases susceptibility of ventricular function to chronic adrenergic stress

(2007) Carly LaCroix et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Calcium Cycling and Signaling in Cardiac Myocytes

(2007) Donald M. Bers   Annual Review of Physiology

Potential clinical relevance of the ‘little brain’ on the mammalian heart

(2007) J. A. Armour   EXPERIMENTAL PHYSIOLOGY

Neuropeptide Y reduces acetylcholine release and vagal bradycardia via a Y2 receptor-mediated, protein kinase C-dependent pathway

(2007) Neil Herring et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY