DNMT3B overexpression downregulates genes with CpG islands, common motifs, and transcription factor binding sites that interact with DNMT3B
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Title
DNMT3B overexpression downregulates genes with CpG islands, common motifs, and transcription factor binding sites that interact with DNMT3B
Authors
Keywords
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Journal
Scientific Reports
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2022-12-02
DOI
10.1038/s41598-022-24186-6
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Note: Only part of the references are listed.- DNA methyltransferase 3 beta regulates promoter methylation of microRNA-149 to augment esophageal squamous cell carcinoma development through the ring finger protein 2/Wnt/β-catenin axis
- (2022) Junfeng Yang et al. Bioengineered
- Intragenic CpG Islands and Their Impact on Gene Regulation
- (2022) James A. Cain et al. Frontiers in Cell and Developmental Biology
- Hepatocellular carcinoma evades RB1-induced senescence by activating the FOXM1–FOXO1 axis
- (2022) Vaibhav Chand et al. ONCOGENE
- Structure of the DNMT3B ADD domain suggests the absence of a DNMT3A-like autoinhibitory mechanism
- (2022) Konstantin Boyko et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- PCDH17 is regulated by methylation of DNMT3B and affects the malignant biological behavior of HCC through EMT
- (2022) Yan Liu et al. EXPERIMENTAL CELL RESEARCH
- Dnmt3b catalytic activity is critical for its tumour suppressor function in lymphomagenesis and is associated with c-Met oncogenic signalling
- (2021) Katarina Lopusna et al. EBioMedicine
- FOXC1 promotes HCC proliferation and metastasis by Upregulating DNMT3B to induce DNA Hypermethylation of CTH promoter
- (2021) Zhuoying Lin et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- QSER1 protects DNA methylation valleys from de novo methylation
- (2021) Gary Dixon et al. SCIENCE
- Interaction between DNMT3B and MYH11 via hypermethylation regulates gastric cancer progression
- (2021) Jianhua Wang et al. BMC CANCER
- TCF3 is epigenetically silenced by EZH2 and DNMT3B and functions as a tumor suppressor in endometrial cancer
- (2021) Tao Gui et al. CELL DEATH AND DIFFERENTIATION
- Deep Enzymology Studies on DNA Methyltransferases Reveal Novel Connections between Flanking Sequences and Enzyme Activity
- (2021) Albert Jeltsch et al. JOURNAL OF MOLECULAR BIOLOGY
- REX-1 Represses RASSF1a and Activates the MEK/ERK Pathway to Promote Tumorigenesis in Prostate Cancer
- (2021) Weijing Liu et al. MOLECULAR CANCER RESEARCH
- ZEB1 Induces Ddr1 Promoter Hypermethylation and Contributes to the Chronic Pain in Spinal Cord in Rats Following Oxaliplatin Treatment
- (2021) Yi-Ying Chen et al. NEUROCHEMICAL RESEARCH
- DNMT3A and DNMT3B Targeting as an Effective Radiosensitizing Strategy in Embryonal Rhabdomyosarcoma
- (2021) Simona Camero et al. Cells
- Structural insights into CpG-specific DNA methylation by human DNA methyltransferase 3B
- (2020) Chien-Chu Lin et al. NUCLEIC ACIDS RESEARCH
- Transcription of intragenic CpG islands influences spatiotemporal host gene pre-mRNA processing
- (2020) Samuele M Amante et al. NUCLEIC ACIDS RESEARCH
- Identification of distinct loci for de novo DNA methylation by DNMT3A and DNMT3B during mammalian development
- (2020) Masaki Yagi et al. Nature Communications
- Comprehensive structure-function characterization of DNMT3B and DNMT3A reveals distinctive de novo DNA methylation mechanisms
- (2020) Linfeng Gao et al. Nature Communications
- Promoter CpG Density Predicts Downstream Gene Loss-of-Function Intolerance
- (2020) Leandros Boukas et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Complex DNA sequence readout mechanisms of the DNMT3B DNA methyltransferase
- (2020) Michael Dukatz et al. NUCLEIC ACIDS RESEARCH
- DNMT3B Expression Might Contribute to Abnormal Methylation of RASSF1A in Lager Colorectal Adenomatous Polyps
- (2020) Xianmei Meng et al. Gastroenterology Research and Practice
- Landscape of Genome-Wide DNA Methylation of Colorectal Cancer Metastasis
- (2020) Carmen Ili et al. Cancers
- DNMT3B silencing suppresses migration and invasion by epigenetically promoting miR-34a in bladder cancer
- (2020) Kai Xu et al. Aging-US
- Flanking sequence preference modulates de novo DNA methylation in the mouse genome
- (2020) Izaskun Mallona et al. NUCLEIC ACIDS RESEARCH
- miR-29c-3p regulates DNMT3B and LATS1 methylation to inhibit tumor progression in hepatocellular carcinoma
- (2019) Hao Wu et al. Cell Death & Disease
- TBX2 interacts with heterochromatin protein 1 to recruit a novel repression complex to EGR1-targeted promoters to drive the proliferation of breast cancer cells
- (2019) N. T. Crawford et al. ONCOGENE
- Sensitivity of transcription factors to DNA methylation
- (2019) Éléa Héberlé et al. Essays in Biochemistry
- Catalytically inactive Dnmt3b rescues mouse embryonic development by accessory and repressive functions
- (2019) Pawel Nowialis et al. Nature Communications
- Telomerase reverse transcriptase regulates DNMT3B expression/aberrant DNA methylation phenotype and AKT activation in hepatocellular carcinoma
- (2018) Jingya Yu et al. CANCER LETTERS
- OUP accepted manuscript
- (2018) NUCLEIC ACIDS RESEARCH
- Targets and genomic constraints of ectopic Dnmt3b expression
- (2018) Yingying Zhang et al. eLife
- Epigenetic restriction of extraembryonic lineages mirrors the somatic transition to cancer
- (2017) Zachary D. Smith et al. NATURE
- A DNA methylation map of human cancer at single base-pair resolution
- (2017) E Vidal et al. ONCOGENE
- Intragenic CpG islands play important roles in bivalent chromatin assembly of developmental genes
- (2017) Sun-Min Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA methylation of intragenic CpG islands depends on their transcriptional activity during differentiation and disease
- (2017) Danuta M. Jeziorska et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dnmt3b Methylates DNA by a Noncooperative Mechanism, and Its Activity Is Unaffected by Manipulations at the Predicted Dimer Interface
- (2016) Allison B. Norvil et al. BIOCHEMISTRY
- Increased DNA methylation of Dnmt3b targets impairs leukemogenesis
- (2016) I. Schulze et al. BLOOD
- Dnmt3a and Dnmt3b Associate with Enhancers to Regulate Human Epidermal Stem Cell Homeostasis
- (2016) Lorenzo Rinaldi et al. Cell Stem Cell
- Loss of Dnmt3b accelerates MLL-AF9 leukemia progression
- (2016) Y Zheng et al. LEUKEMIA
- Lin28A Binds Active Promoters and Recruits Tet1 to Regulate Gene Expression
- (2016) Yaxue Zeng et al. MOLECULAR CELL
- Mapping of Variable DNA Methylation Across Multiple Cell Types Defines a Dynamic Regulatory Landscape of the Human Genome
- (2016) Junchen Gu et al. G3-Genes Genomes Genetics
- Establishment of a DNA methylation marker to evaluate cancer cell fraction in gastric cancer
- (2015) Liang Zong et al. Gastric Cancer
- Genomic profiling of DNA methyltransferases reveals a role for DNMT3B in genic methylation
- (2015) Tuncay Baubec et al. NATURE
- Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells
- (2015) Jing Liao et al. NATURE GENETICS
- Genome-wide profiling of DNA methylation reveals preferred sequences of DNMTs in hepatocellular carcinoma cells
- (2015) Hong Fan et al. TUMOR BIOLOGY
- Aberrant DNA hypermethylation reduces the expression of the desmosome-related molecule periplakin in esophageal squamous cell carcinoma
- (2015) Takeshi Otsubo et al. Cancer Medicine
- Reprogramming the Methylome: Erasing Memory and Creating Diversity
- (2014) Heather J. Lee et al. Cell Stem Cell
- The BRAF Oncoprotein Functions through the Transcriptional Repressor MAFG to Mediate the CpG Island Methylator Phenotype
- (2014) Minggang Fang et al. MOLECULAR CELL
- Global identification of genes targeted by DNMT3b for epigenetic silencing in lung cancer
- (2014) I Teneng et al. ONCOGENE
- Notes on the role of dynamic DNA methylation in mammalian development
- (2014) Timothy H. Bestor et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Analysis of DNA methylation change induced by Dnmt3b in mouse hepatocytes
- (2013) Mayumi Takahashi et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Charting a dynamic DNA methylation landscape of the human genome
- (2013) Michael J. Ziller et al. NATURE
- DNA methylation presents distinct binding sites for human transcription factors
- (2013) Shaohui Hu et al. eLife
- LRpath analysis reveals common pathways dysregulated via DNA methylation across cancer types
- (2012) Jung H Kim et al. BMC GENOMICS
- Clinicopathologic significance of DNA methyltransferase 1, 3a, and 3b overexpression in Tunisian breast cancers
- (2012) Riadh Ben Gacem et al. HUMAN PATHOLOGY
- Genes methylated by DNA methyltransferase 3b are similar in mouse intestine and human colon cancer
- (2011) Eveline J. Steine et al. JOURNAL OF CLINICAL INVESTIGATION
- DNA-binding factors shape the mouse methylome at distal regulatory regions
- (2011) Michael B. Stadler et al. NATURE
- Identification of genetic elements that autonomously determine DNA methylation states
- (2011) Florian Lienert et al. NATURE GENETICS
- Cis-regulatory elements: molecular mechanisms and evolutionary processes underlying divergence
- (2011) Patricia J. Wittkopp et al. NATURE REVIEWS GENETICS
- DNA methyltransferase 3b preferentially associates with condensed chromatin
- (2011) Katsunobu Kashiwagi et al. NUCLEIC ACIDS RESEARCH
- MTSS1, a novel target of DNA methyltransferase 3B, functions as a tumor suppressor in hepatocellular carcinoma
- (2011) H Fan et al. ONCOGENE
- Prediction of epigenetically regulated genes in breast cancer cell lines
- (2010) Leandro A Loss et al. BMC BIOINFORMATICS
- Dnmt3/transcription factor interactions as crucial players in targeted DNA methylation
- (2010) Eric Hervouet et al. Epigenetics
- HOXB13, a Target of DNMT3B, Is Methylated at an Upstream CpG Island, and Functions as a Tumor Suppressor in Primary Colorectal Tumors
- (2010) Kalpana Ghoshal et al. PLoS One
- DNMT3L Modulates Significant and Distinct Flanking Sequence Preference for DNA Methylation by DNMT3A and DNMT3B In Vivo
- (2010) Bethany L. Wienholz et al. PLoS Genetics
- Frequent loss of heterozygosity at the interferon regulatory factor-1 gene locus in breast cancer
- (2009) Luciane R. Cavalli et al. BREAST CANCER RESEARCH AND TREATMENT
- Profiling the Human Protein-DNA Interactome Reveals ERK2 as a Transcriptional Repressor of Interferon Signaling
- (2009) Shaohui Hu et al. CELL
- CpG islands - ‘A rough guide’
- (2009) Robert S. Illingworth et al. FEBS LETTERS
- Selective Anchoring of DNA Methyltransferases 3A and 3B to Nucleosomes Containing Methylated DNA
- (2009) S. Jeong et al. MOLECULAR AND CELLULAR BIOLOGY
- Epigenetic Silencing of the RASSF1A Tumor Suppressor Gene through HOXB3-Mediated Induction of DNMT3B Expression
- (2009) Rajendra Kumar Palakurthy et al. MOLECULAR CELL
- The IRF Family Transcription Factors in Immunity and Oncogenesis
- (2008) Tomohiko Tamura et al. Annual Review of Immunology
- DNMT3b overexpression contributes to a hypermethylator phenotype in human breast cancer cell lines
- (2008) J Devon Roll et al. Molecular Cancer
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