Synthesis of warfarin analogs: conjugate addition reactions of alkenyl-substituted N-heterocycles with 4-hydroxycoumarin and related substrates

Double Addition Reactions Involving Vinyl-Substituted N-Heterocycles and Active Methylene Compounds

(2022) Jacob C. Hood et al.   JOURNAL OF ORGANIC CHEMISTRY

Enantioselective [3 + 2] Cycloaddition of Vinylcyclopropanes with Alkenyl N-Heteroarenes Enabled by Palladium Catalysis

(2022) Wen-Dao Chu et al.   ORGANIC LETTERS

Enantioselective Conjugate Addition of Alkenyl Trifluoroborates to Alkenyl-Substituted Benzimidazoles Catalyzed by Chiral Binaphthols

(2022) Bin Mao et al.   ORGANIC LETTERS

Development of a DABCO-Succinic Acid Based Catalytic System for the Aza-Michael Addition and Aza-Michael/Knoevenagel Tandem Reaction of Thiazolidine-2,4-dione to Electron Deficient Alkenes

(2021) Kilsoo Jung et al.   JOURNAL OF ORGANIC CHEMISTRY

Scandium-catalyzed Michael addition of quinazolinones and vinylazaarenes

(2020) Zhiguang Zhang et al.   TETRAHEDRON LETTERS

An insight into the therapeutic applications of coumarin compounds and their mechanisms of action

(2020) Sourbh Suren Garg et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Michael Addition with an Olefinic Pyridine: Organometallic Nucleophiles and Carbon Electrophiles

(2020) Michael R. Stentzel et al.   JOURNAL OF ORGANIC CHEMISTRY

Organocatalytic aza-Michael Reaction to 3-Vinyl-1,2,4-triazines as a Valuable Bifunctional Platform

(2019) Floris Buttard et al.   JOURNAL OF ORGANIC CHEMISTRY

New selective cyclooxygenase-2 inhibitors from cyclocoumarol: Synthesis, characterization, biological evaluation and molecular modeling

(2018) Anita Marie Rayar et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Michael Additions Involving Amino Acid Esters with Alkenyl N-Heterocycles

(2017) Sean H. Kennedy et al.   JOURNAL OF ORGANIC CHEMISTRY

Highly enantioselective catalytic synthesis of chiral pyridines

(2017) Ravindra P. Jumde et al.   Nature Communications

Catalytic asymmetric addition of Grignard reagents to alkenyl-substituted aromatic N-heterocycles

(2016) R. P. Jumde et al.   SCIENCE

Enantioselective Aza Michael-Type Addition to Alkenyl Benzimidazoles Catalyzed by a Chiral Phosphoric Acid

(2015) Ya-Yi Wang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Organocatalytic Enantioselective Direct Additions of Aldehydes to 4-Vinylpyridines and Electron-Deficient Vinylarenes and Their Synthetic Applications

(2015) Sinan Wang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Highly enantioselective synthesis of Warfarin and its analogs catalysed by primary amine–phosphinamide bifunctional catalysts

(2012) Juan Dong et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

Conjugate Additions to Vinyl-Substituted Aromatic N-Heterocycles

(2012) Douglas Klumpp   SYNLETT

The story of the discovery of heparin and warfarin

(2008) Douglas Wardrop et al.   BRITISH JOURNAL OF HAEMATOLOGY