Hydrophobicity of arginine leads to reentrant liquid-liquid phase separation behaviors of arginine-rich proteins

Evidence for Entropically Controlled Interfacial Hydration in Mesoporous Organosilicas

(2022) Hyunjin Moon et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phase-separating peptides for direct cytosolic delivery and redox-activated release of macromolecular therapeutics

(2022) Yue Sun et al.   Nature Chemistry

Biomolecular Condensates: Sequence Determinants of Phase Separation, Microstructural Organization, Enzymatic Activity, and Material Properties

(2021) Benjamin S. Schuster et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Reentrant liquid condensate phase of proteins is stabilized by hydrophobic and non-ionic interactions

(2021) Georg Krainer et al.   Nature Communications

Physics-based computational and theoretical approaches to intrinsically disordered proteins

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Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

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Label‐Free Quantitative Analysis of Coacervates via 3D Phase Imaging

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Unexpected aqueous UCST behavior of a cationic comb polymer with pentaarginine side chains

(2020) Nicolas Zydziak et al.   EUROPEAN POLYMER JOURNAL

Arginine-Enriched Mixed-Charge Domains Provide Cohesion for Nuclear Speckle Condensation

(2020) Jamie A. Greig et al.   MOLECULAR CELL

Biomolecular Phase Separation: From Molecular Driving Forces to Macroscopic Properties

(2020) Gregory L. Dignon et al.   Annual Review of Physical Chemistry

G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules

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Identifying sequence perturbations to an intrinsically disordered protein that determine its phase-separation behavior

(2020) Benjamin S. Schuster et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein Encapsulation Using Complex Coacervates: What Nature Has to Teach Us

(2020) Whitney C. Blocher McTigue et al.   Small

Dehydration entropy drives liquid-liquid phase separation by molecular crowding

(2020) Sohee Park et al.   Communications Chemistry

Unraveling Molecular Interactions in Liquid–Liquid Phase Separation of Disordered Proteins by Atomistic Simulations

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Tunable multiphase dynamics of arginine and lysine liquid condensates

(2020) Rachel S. Fisher et al.   Nature Communications

Liquid-Liquid Phase Separation of Tau Driven by Hydrophobic Interaction Facilitates Fibrillization of Tau

(2020) Yanxian Lin et al.   JOURNAL OF MOLECULAR BIOLOGY

Complete Phase Diagram for Liquid–Liquid Phase Separation of Intrinsically Disordered Proteins

(2019) James McCarty et al.   Journal of Physical Chemistry Letters

Characterizing Solvent Density Fluctuations in Dynamical Observation Volumes

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Aqueous Liquid-Liquid Phase Separation of Natural and Synthetic Polyguanidiniums

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Upper Critical Solution Temperature (UCST) Behavior of Coacervate of Cationic Protamine and Multivalent Anions

(2019) Hyungbin Kim et al.   Polymers

Arginine “Magic”: Guanidinium Like-Charge Ion Pairing from Aqueous Salts to Cell Penetrating Peptides

(2018) Mario Vazdar et al.   ACCOUNTS OF CHEMICAL RESEARCH

A Molecular Grammar Governing the Driving Forces for Phase Separation of Prion-like RNA Binding Proteins

(2018) Jie Wang et al.   CELL

FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions

(2018) Seema Qamar et al.   CELL

RGG/RG Motif Regions in RNA Binding and Phase Separation

(2018) P. Andrew Chong et al.   JOURNAL OF MOLECULAR BIOLOGY

Protein Phase Separation: A New Phase in Cell Biology

(2018) Steven Boeynaems et al.   TRENDS IN CELL BIOLOGY

Pi-Pi contacts are an overlooked protein feature relevant to phase separation

(2018) Robert McCoy Vernon et al.   eLife

Controllable protein phase separation and modular recruitment to form responsive membraneless organelles

(2018) Benjamin S. Schuster et al.   Nature Communications

Protamine nanocapsules as carriers for oral peptide delivery

(2018) Lungile Nomcebo Thwala et al.   JOURNAL OF CONTROLLED RELEASE

Stratified UWHAM and Its Stochastic Approximation for Multicanonical Simulations Which Are Far from Equilibrium

(2017) Bin W. Zhang et al.   Journal of Chemical Theory and Computation

Quinary Interactions Weaken the Electric Field Generated by Protein Side-Chain Charges in the Cell-like Environment

(2017) Ning Zhang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Phase Separation of C9orf72 Dipeptide Repeats Perturbs Stress Granule Dynamics

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Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Intrinsically Disordered Proteome of Human Membrane-Less Organelles

(2017) April L. Darling et al.   PROTEOMICS

Sequence and entropy-based control of complex coacervates

(2017) Li-Wei Chang et al.   Nature Communications

Bicontinuous Fluid Structure with Low Cohesive Energy: Molecular Basis for Exceptionally Low Interfacial Tension of Complex Coacervate Fluids

(2016) Kuo-Ying Huang et al.   ACS Nano

C9orf72 Dipeptide Repeats Impair the Assembly, Dynamics, and Function of Membrane-Less Organelles

(2016) Kyung-Ha Lee et al.   CELL

Consensus on the solubility of NaCl in water from computer simulations using the chemical potential route

(2016) A. L. Benavides et al.   JOURNAL OF CHEMICAL PHYSICS

An mRNA Vaccine Encoding Rabies Virus Glycoprotein Induces Protection against Lethal Infection in Mice and Correlates of Protection in Adult and Newborn Pigs

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Phase Separation by Low Complexity Domains Promotes Stress Granule Assembly and Drives Pathological Fibrillization

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A Liquid-to-Solid Phase Transition of the ALS Protein FUS Accelerated by Disease Mutation

(2015) Avinash Patel et al.   CELL

Anomalously Rapid Hydration Water Diffusion Dynamics Near DNA Surfaces

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Classification of Intrinsically Disordered Regions and Proteins

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Balanced Protein–Water Interactions Improve Properties of Disordered Proteins and Non-Specific Protein Association

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Hydration of Guanidinium: Second Shell Formation at Small Cluster Size

(2014) Richard J. Cooper et al.   JOURNAL OF PHYSICAL CHEMISTRY A

Surface Behavior of Hydrated Guanidinium and Ammonium Ions: A Comparative Study by Photoelectron Spectroscopy and Molecular Dynamics

(2014) Josephina Werner et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Efficient Method To Characterize the Context-Dependent Hydrophobicity of Proteins

(2014) Amish J. Patel et al.   JOURNAL OF PHYSICAL CHEMISTRY B

A mussel-derived one component adhesive coacervate

(2013) Wei Wei et al.   Acta Biomaterialia

Defining the RGG/RG Motif

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A nuclear F-actin scaffold stabilizes ribonucleoprotein droplets against gravity in large cells

(2013) Marina Feric et al.   NATURE CELL BIOLOGY

Quantitative cw Overhauser effect dynamic nuclear polarization for the analysis of local water dynamics

(2013) John M. Franck et al.   PROGRESS IN NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY

Fluidity and water in nanoscale domains define coacervate hydrogels

(2013) Julia H. Ortony et al.   Chemical Science

Intrinsically disordered proteins: a 10-year recap

(2012) Peter Tompa   TRENDS IN BIOCHEMICAL SCIENCES

Quantifying Density Fluctuations in Volumes of All Shapes and Sizes Using Indirect Umbrella Sampling

(2011) Amish J. Patel et al.   JOURNAL OF STATISTICAL PHYSICS

Analysis of the Complex Formation of Heparin with Protamine by Light Scattering and Analytical Ultracentrifugation: Implications for Blood Coagulation Management

(2010) Jürgen Maurer et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Isothermal-isobaric molecular dynamics using stochastic velocity rescaling

(2009) Giovanni Bussi et al.   JOURNAL OF CHEMICAL PHYSICS

Protonated Arginine and Protonated Lysine: Hydration and Its Effect on the Stability of Salt-Bridge Structures

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The Molecular Origin of Like-Charge Arginine−Arginine Pairing in Water

(2009) Jiří Vondrášek et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Overhauser Dynamic Nuclear Polarization To Study Local Water Dynamics

(2009) Brandon D. Armstrong et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

GROMACS 4:  Algorithms for Highly Efficient, Load-Balanced, and Scalable Molecular Simulation

(2008) Berk Hess et al.   Journal of Chemical Theory and Computation

Water as an Active Constituent in Cell Biology

(2007) Philip Ball   CHEMICAL REVIEWS