FRMD3 inhibits the growth and metastasis of breast cancer through the ubiquitination-mediated degradation of vimentin and subsequent impairment of focal adhesion

Vimentin tunes cell migration on collagen by controlling β1 integrin activation and clustering

(2021) Zofia Ostrowska-Podhorodecka et al.   JOURNAL OF CELL SCIENCE

PLK1/vimentin signaling facilitates immune escape by recruiting Smad2/3 to PD-L1 promoter in metastatic lung adenocarcinoma

(2021) Hay-Ran Jang et al.   CELL DEATH AND DIFFERENTIATION

The role of filamins in mechanically stressed podocytes

(2021) Jonas K. Greiten et al.   FASEB JOURNAL

Breast cancer

(2021) Sibylle Loibl et al.   LANCET

WD40 repeat 43 mediates cell survival, proliferation, migration and invasion via vimentin in colorectal cancer

(2021) Zijian Li et al.   Cancer Cell International

Metastatic Breast Cancer, Organotropism and Therapeutics: A Review

(2021) Ajaz Ahmad Waza et al.   CURRENT CANCER DRUG TARGETS

High FRMD3 expression is prognostic for worse survival in rectal cancer patients treated with CCRT

(2021) Tzu-Ju Chen et al.   International Journal of Clinical Oncology

Role of Extracellular Vimentin in Cancer-Cell Functionality and Its Influence on Cell Monolayer Permeability Changes Induced by SARS-CoV-2 Receptor Binding Domain

(2021) Divyendu Goud Thalla et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Vimentin intermediate filaments stabilize dynamic microtubules by direct interactions

(2021) Laura Schaedel et al.   Nature Communications

Hsa-miR-3651 could serve as a novel predictor for in-breast recurrence via FRMD3

(2021) Barbara Zellinger et al.   Breast Cancer

Dysregulation of Cytoskeleton Remodeling Drives Invasive Leading Cells Detachment

(2021) Jei-Ming Peng et al.   Cancers

Genetic associated complications of type 2 diabetes mellitus

(2021) Yee H. WONG et al.   PANMINERVA MEDICA

Vimentin Intermediate Filaments as Potential Target for Cancer Treatment

(2020) Katerina Strouhalova et al.   Cancers

Regulation of the Actin Cytoskeleton in Podocytes

(2020) Judith Blaine et al.   Cells

Cooperative roles of PAK1 and filamin A in regulation of vimentin assembly and cell extension formation

(2020) Isabel Ding et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

AKT-induced lncRNA VAL promotes EMT-independent metastasis through diminishing Trim16-dependent Vimentin degradation

(2020) Han Tian et al.   Nature Communications

Involvement of Actin and Actin-Binding Proteins in Carcinogenesis

(2020) Magdalena Izdebska et al.   Cells

Regulatory mechanisms and clinical significance of vimentin in breast cancer

(2020) Zhilong Chen et al.   BIOMEDICINE & PHARMACOTHERAPY

ORAI2 Promotes Gastric Cancer Tumorigenicity and Metastasis Through PI3K/Akt Signaling and MAPK-dependent Focal Adhesion Disassembly

(2020) Shayi Wu et al.   CANCER RESEARCH

Characterization of Triple-Negative Breast Cancer Preclinical Models Provides Functional Evidence of Metastatic Progression

(2019) Juan J. Arroyo-Crespo et al.   INTERNATIONAL JOURNAL OF CANCER

SEPT9_i1 regulates human breast cancer cell motility through cytoskeletal and RhoA/FAK signaling pathway regulation

(2019) Yongqiu Zeng et al.   Cell Death & Disease

Breast cancer

(2019) Nadia Harbeck et al.   Nature Reviews Disease Primers

The Multifaceted p21 (Cip1/Waf1/CDKN1A) in Cell Differentiation, Migration and Cancer Therapy

(2019) Kreis et al.   Cancers

Characterization of the Roles of Vimentin in Regulating the Proliferation and Migration of HSCs during Hepatic Fibrogenesis

(2019) Pei-Wen Wang et al.   Cells

RNF208, an estrogen-inducible E3 ligase, targets soluble Vimentin to suppress metastasis in triple-negative breast cancers

(2019) Kyoungwha Pang et al.   Nature Communications

The MTM1–UBQLN2–HSP complex mediates degradation of misfolded intermediate filaments in skeletal muscle

(2018) Christos Gavriilidis et al.   NATURE CELL BIOLOGY

IRE1α governs cytoskeleton remodelling and cell migration through a direct interaction with filamin A

(2018) Hery Urra et al.   NATURE CELL BIOLOGY

MiR-22 suppresses epithelial–mesenchymal transition in bladder cancer by inhibiting Snail and MAPK1/Slug/vimentin feedback loop

(2018) Mingjie Xu et al.   Cell Death & Disease

Quantitative in vivo whole genome motility screen reveals novel therapeutic targets to block cancer metastasis

(2018) Konstantin Stoletov et al.   Nature Communications

Integrin activation by talin, kindlin and mechanical forces

(2018) Zhiqi Sun et al.   NATURE CELL BIOLOGY

The ubiquitin ligase TRIM56 inhibits ovarian cancer progression by targeting vimentin

(2017) Lei Zhao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Upholding a role for EMT in breast cancer metastasis

(2017) Xin Ye et al.   NATURE

Mechanical Properties of the Cytoskeleton and Cells

(2017) Adrian F. Pegoraro et al.   Cold Spring Harbor Perspectives in Biology

UALCAN: A Portal for Facilitating Tumor Subgroup Gene Expression and Survival Analyses

(2017) Darshan S. Chandrashekar et al.   NEOPLASIA

Vimentin coordinates fibroblast proliferation and keratinocyte differentiation in wound healing via TGF-β–Slug signaling

(2016) Fang Cheng et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein 4.1G Regulates Cell Adhesion, Spreading, and Migration of Mouse Embryonic Fibroblasts through the β1 Integrin Pathway

(2015) Lixiang Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Testes-specific protease 50 promotes cell invasion and metastasis by increasing NF-kappaB-dependent matrix metalloproteinase-9 expression

(2015) Z B Song et al.   Cell Death & Disease

FRMD3 gene: its role in diabetic kidney disease. A narrative review

(2015) Marjoriê Piuco Buffon et al.   Diabetology & Metabolic Syndrome

Vimentin contributes to epithelial-mesenchymal transition cancer cell mechanics by mediating cytoskeletal organization and focal adhesion maturation

(2015) Ching-Yi Liu et al.   Oncotarget

FERM family proteins and their importance in cellular movements and wound healing (Review)

(2014) DAVID C. BOSANQUET et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Vimentin regulates lung cancer cell adhesion through a VAV2–Rac1 pathway to control focal adhesion kinase activity

(2014) L S Havel et al.   ONCOGENE

The Protein 4.1 family: Hub proteins in animals for organizing membrane proteins

(2013) Anthony J. Baines et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

FRMD3 in diabetic nephropathy—guilt by association

(2013) Nicholette D. Palmer et al.   Nature Reviews Nephrology

Vimentin in cancer and its potential as a molecular target for cancer therapy

(2011) Arun Satelli et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The FERM domain: organizing the structure and function of FAK

(2010) Margaret C. Frame et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY