Neglected no more: B cell-mediated anti-tumor immunity

TGF-β-mediated silencing of genomic organizer SATB1 promotes Tfh cell differentiation and formation of intra-tumoral tertiary lymphoid structures

(2022) Ricardo A. Chaurio et al.   IMMUNITY

Tertiary lymphoid structures in cancer

(2022) Ton N. Schumacher et al.   SCIENCE

Intratumoral plasma cells predict outcomes to PD-L1 blockade in non-small cell lung cancer

(2022) Namrata S. Patil et al.   CANCER CELL

Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells

(2022) Carmen M. Anadon et al.   CANCER CELL

Tumor-reactive antibodies evolve from non-binding and autoreactive precursors

(2022) Roei D. Mazor et al.   CELL

Tertiary lymphoid structures generate and propagate anti-tumor antibody-producing plasma cells in renal cell cancer

(2022) Maxime Meylan et al.   IMMUNITY

Olfactory Receptor OR2H1 is an effective target for CAR T cells in human epithelial tumors

(2022) Alexandra L. Martin et al.   MOLECULAR CANCER THERAPEUTICS

B cells and tertiary lymphoid structures as determinants of tumour immune contexture and clinical outcome

(2022) Wolf H. Fridman et al.   Nature Reviews Clinical Oncology

Leucine-tRNA-synthetase-2-expressing B cells contribute to colorectal cancer immunoevasion

(2022) Zhiqiang Wang et al.   IMMUNITY

IgA transcytosis and antigen recognition govern ovarian cancer immunity

(2021) Subir Biswas et al.   NATURE

STINGing the Tumor Microenvironment to Promote Therapeutic Tertiary Lymphoid Structure Development

(2021) Jessica N. Filderman et al.   Frontiers in Immunology

Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes in Triple-Negative Breast Cancer

(2021) Robert J. Harris et al.   CANCER RESEARCH

Using oncolytic viruses to ignite the tumour immune microenvironment in bladder cancer

(2021) Roger Li et al.   Nature Reviews Urology

B cells and cancer

(2021) Victor Engelhard et al.   CANCER CELL

IgA-dominated humoral immune responses govern patients' outcome in endometrial cancer

(2021) Gunjan Mandal et al.   CANCER RESEARCH

Microbiota-specific T follicular helper cells drive tertiary lymphoid structures and anti-tumor immunity against colorectal cancer

(2021) Abigail E. Overacre-Delgoffe et al.   IMMUNITY

Immune Landscape of Viral- and Carcinogen-Driven Head and Neck Cancer

(2020) Anthony R. Cillo et al.   IMMUNITY

B cells are associated with survival and immunotherapy response in sarcoma

(2020) Florent Petitprez et al.   NATURE

Tertiary lymphoid structures improve immunotherapy and survival in melanoma

(2020) Rita Cabrita et al.   NATURE

B cells and tertiary lymphoid structures promote immunotherapy response

(2020) Beth A. Helmink et al.   NATURE

The dangers of déjà vu: Memory B-cells as the cell-of-origin of ABC-DLBCLs

(2020) Leandro Venturutti et al.   BLOOD

BTK signaling drives CD1dhiCD5+ regulatory B-cell differentiation to promote pancreatic carcinogenesis

(2019) Shipra Das et al.   ONCOGENE

Landscape of infiltrating B cells and their clinical significance in human hepatocellular carcinoma

(2019) Zhao Zhang et al.   OncoImmunology

Landscape of B cell immunity and related immune evasion in human cancers

(2019) Xihao Hu et al.   NATURE GENETICS

The Tumor Immune Microenvironment Drives a Prognostic Relevance that Correlates with Bladder Cancer Subtypes

(2019) Carolin Pfannstiel et al.   Cancer Immunology Research

Human Colorectal Carcinoma Infiltrating B Lymphocytes Are Active Secretors of the Immunoglobulin Isotypes A, G, and M

(2019) Christina Susanne Mullins et al.   Cancers

B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer

(2019) Daniel P. Hollern et al.   CELL

Exosomes Produced by Mesenchymal Stem Cells Drive Differentiation of Myeloid Cells into Immunosuppressive M2-Polarized Macrophages in Breast Cancer

(2019) Subir Biswas et al.   JOURNAL OF IMMUNOLOGY

B Regulatory Cells: Players in Pregnancy and Early Life

(2018) Ana Esteve-Solé et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Immune Cell Infiltration and Tertiary Lymphoid Structures as Determinants of Antitumor Immunity

(2018) Victor H. Engelhard et al.   JOURNAL OF IMMUNOLOGY

Presence of tertiary lymphoid structures determines the level of tumor-infiltrating lymphocytes in primary breast cancer and metastasis

(2018) Miseon Lee et al.   MODERN PATHOLOGY

Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy

(2018) Terry R. Medler et al.   CANCER CELL

Gene landscape and correlation between B-cell infiltration and programmed death ligand 1 expression in lung adenocarcinoma patients from The Cancer Genome Atlas data set

(2018) Kuo-Hao Ho et al.   PLoS One

Antigen Specificity and Clinical Significance of IgG and IgA Autoantibodies Produced in situ by Tumor-Infiltrating B Cells in Breast Cancer

(2018) Soizic Garaud et al.   Frontiers in Immunology

Polymeric immunoglobulin receptor promotes tumor growth in hepatocellular carcinoma

(2017) Xihua Yue et al.   HEPATOLOGY

Inflammation-induced IgA+ cells dismantle anti-liver cancer immunity

(2017) Shabnam Shalapour et al.   NATURE

Expression of polymeric immunoglobulin receptor and stromal activity in pancreatic ductal adenocarcinoma

(2017) Prabhu Arumugam et al.   PANCREATOLOGY

Immune Checkpoint Molecules on Tumor-Infiltrating Lymphocytes and Their Association with Tertiary Lymphoid Structures in Human Breast Cancer

(2017) Cinzia Solinas et al.   Frontiers in Immunology

IL-10+ regulatory B cells are enriched in cord blood and may protect against cGVHD after cord blood transplantation

(2016) A. Sarvaria et al.   BLOOD

Tumor-Infiltrating Plasma Cells Are Associated with Tertiary Lymphoid Structures, Cytolytic T-Cell Responses, and Superior Prognosis in Ovarian Cancer

(2016) D. R. Kroeger et al.   CLINICAL CANCER RESEARCH

Tertiary lymphoid structures, drivers of the anti-tumor responses in human cancers

(2016) Marie-Caroline Dieu-Nosjean et al.   IMMUNOLOGICAL REVIEWS

Mammary-tumor-educated B cells acquire LAP/TGF-β and PD-L1 expression and suppress anti-tumor immune responses

(2016) Yu Zhang et al.   INTERNATIONAL IMMUNOLOGY

Plasma cells in primary melanoma. Prognostic significance and possible role of IgA

(2016) Francesca M Bosisio et al.   MODERN PATHOLOGY

Tertiary Lymphoid Structures in Cancers: Prognostic Value, Regulation, and Manipulation for Therapeutic Intervention

(2016) Catherine Sautès-Fridman et al.   Frontiers in Immunology

Intratumoral tertiary lymphoid organ is a favourable prognosticator in patients with pancreatic cancer

(2015) N Hiraoka et al.   BRITISH JOURNAL OF CANCER

Immunosuppressive and Prometastatic Functions of Myeloid-Derived Suppressive Cells Rely upon Education from Tumor-Associated B Cells

(2015) M. Bodogai et al.   CANCER RESEARCH

Regulatory B Cells: Origin, Phenotype, and Function

(2015) Elizabeth C. Rosser et al.   IMMUNITY

Regulatory B10 cell development and function: Fig. 1.

(2015) Jacquelyn M. Lykken et al.   INTERNATIONAL IMMUNOLOGY

The expanding family of regulatory B cells

(2015) Claudia Mauri et al.   INTERNATIONAL IMMUNOLOGY

Tertiary lymphoid structures: prognostic significance and relationship with tumour-infiltrating lymphocytes in triple-negative breast cancer

(2015) Hee Jin Lee et al.   JOURNAL OF CLINICAL PATHOLOGY

Prognostic and predictive significance of immune cells infiltrating cutaneous melanoma

(2015) Andrea Ladányi   Pigment Cell & Melanoma Research

Hif1a Deletion Reveals Pro-Neoplastic Function of B Cells in Pancreatic Neoplasia

(2015) K. E. Lee et al.   Cancer Discovery

Regulatory B cells preferentially accumulate in tumor-draining lymph nodes and promote tumor growth

(2015) Sheila N. Ganti et al.   Scientific Reports

Tumor infiltration by Tbet+ effector T cells and CD20+ B cells is associated with survival in gastric cancer patients

(2015) Audrey Hennequin et al.   OncoImmunology

Occurrence of Tertiary Lymphoid Tissue Is Associated with T-Cell Infiltration and Predicts Better Prognosis in Early-Stage Colorectal Cancers

(2014) G. Di Caro et al.   CLINICAL CANCER RESEARCH

Germinal center reentries of BCL2-overexpressing B cells drive follicular lymphoma progression

(2014) Stéphanie Sungalee et al.   JOURNAL OF CLINICAL INVESTIGATION

IL-35-producing B cells are critical regulators of immunity during autoimmune and infectious diseases

(2014) Ping Shen et al.   NATURE

B Cells and Ectopic Follicular Structures: Novel Players in Anti-Tumor Programming with Prognostic Power for Patients with Metastatic Colorectal Cancer

(2014) Anastasia Meshcheryakova et al.   PLoS One

Immune Regulatory Function of B Cells

(2012) Claudia Mauri et al.   Annual Review of Immunology

The relationships between cellular components of the peritumoural inflammatory response, clinicopathological characteristics and survival in patients with primary operable colorectal cancer

(2012) C H Richards et al.   BRITISH JOURNAL OF CANCER

Neogenesis of Lymphoid Structures and Antibody Responses Occur in Human Melanoma Metastases

(2012) Arcadi Cipponi et al.   CANCER RESEARCH

12-Chemokine Gene Signature Identifies Lymph Node-like Structures in Melanoma: Potential for Patient Selection for Immunotherapy?

(2012) Jane L. Messina et al.   Scientific Reports

B regulatory cells and the tumor-promoting actions of TNF-  during squamous carcinogenesis

(2011) T. Schioppa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FcRγ Activation Regulates Inflammation-Associated Squamous Carcinogenesis

(2010) Pauline Andreu et al.   CANCER CELL

Survival in rectal cancer is predicted by T cell infiltration of tumour-associated lymphoid nodules

(2010) T. P. W. McMullen et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

CD19+CD24hiCD38hi B Cells Exhibit Regulatory Capacity in Healthy Individuals but Are Functionally Impaired in Systemic Lupus Erythematosus Patients

(2010) Paul A. Blair et al.   IMMUNITY

Modulation of the antitumor immune response by complement

(2008) Maciej M Markiewski et al.   NATURE IMMUNOLOGY