Deciphering the “obesity paradox” in the elderly: A systematic review and meta‐analysis of sarcopenic obesity

Definition and diagnostic criteria for sarcopenic obesity: ESPEN and EASO consensus statement

(2022) Lorenzo M. Donini et al.   CLINICAL NUTRITION

Age-Related Skeletal Muscle Dysfunction Is Aggravated by Obesity: An Investigation of Contractile Function, Implications and Treatment

(2021) Jason Tallis et al.   Biomolecules

Updated systematic review and meta-analysis on diagnostic issues and the prognostic impact of myosteatosis: A new paradigm beyond sarcopenia

(2021) Hyemin Ahn et al.   AGEING RESEARCH REVIEWS

Global prevalence of sarcopenic obesity in older adults: A systematic review and meta-analysis

(2021) Qianqian Gao et al.   CLINICAL NUTRITION

Body-mass index and obesity in urban and rural China: findings from consecutive nationally representative surveys during 2004–18

(2021) Limin Wang et al.   LANCET

Periodontal disease and the risk of Alzheimer's disease and mild cognitive impairment: a systematic review and meta‐analysis

(2021) Xin Hu et al.   Psychogeriatrics

Mitochondrial dysfunction in skeletal muscle contributes to the development of acute insulin resistance in mice

(2021) Hyunjung Lee et al.   Journal of Cachexia Sarcopenia and Muscle

Diagnosis of sarcopenia by evaluating skeletal muscle mass by adjusted bioimpedance analysis validated with dual‐energy X‐ray absorptiometry

(2021) Keith Yu‐Kin Cheng et al.   Journal of Cachexia Sarcopenia and Muscle

Higher Serum Leptin Levels are Associated with a Reduced Risk of Sarcopenia but a Higher Risk of Dynapenia Among Older Adults

(2021) Tung-Wei Kao et al.   Journal of Inflammation Research

Sarcopenia, Obesity and Sarcopenia Obesity in Comparison: Prevalence, Metabolic Profile, and Key Differences: Results from WCHAT Study

(2020) X. Liu et al.   Journal of Nutrition Health & Aging

Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment

(2020) Liang-Kung Chen et al.   Journal of the American Medical Directors Association

Obesity and ageing: Two sides of the same coin

(2020) Bjorn T. Tam et al.   Obesity Reviews

Sarcopenic obesity and its association with respiratory disease incidence and mortality

(2020) Fanny Petermann-Rocha et al.   CLINICAL NUTRITION

Effect of sarcopenic obesity on deterioration of physical function in the elderly

(2020) Hyun Ho Kong et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Prevalence and Associated Factors of Sarcopenia in Singaporean Adults—The Yishun Study

(2020) Benedict Wei Jun Pang et al.   Journal of the American Medical Directors Association

The Relationship Between Intermuscular Fat and Physical Performance Is Moderated by Muscle Area in Older Adults

(2020) Samaneh Farsijani et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Worsening Disability and Hospitalization Risk in Sarcopenic Obese and Dynapenic Abdominal Obese: A 5.5 Years Follow-Up Study in Elderly Men and Women

(2020) Andrea P. Rossi et al.   Frontiers in Endocrinology

Sarcopenic obesity: Myokines as potential diagnostic biomarkers and therapeutic targets?

(2020) Ai Guo et al.   EXPERIMENTAL GERONTOLOGY

Incident Impaired Cognitive Function in Sarcopenic Obesity: Data From the National Health and Aging Trends Survey

(2020) John A. Batsis et al.   Journal of the American Medical Directors Association

The Influence of Age and Obesity-Altered Muscle Tissue Composition on Muscular Dimensional Changes: Impact on Strength and Function

(2020) Hayden K Giuliani et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Comparisons of Muscle Quality and Muscle Growth Factor Between Sarcopenic and Non-Sarcopenic Older Women

(2020) Myong-Won Seo et al.   International Journal of Environmental Research and Public Health

Validation of a description of sarcopenic obesity defined as excess adiposity and low lean mass relative to adiposity

(2020) Joshua F. Baker et al.   Journal of Cachexia Sarcopenia and Muscle

Exploring the Impact of Obesity on Skeletal Muscle Function in Older Age

(2020) Paul T. Morgan et al.   Frontiers in Nutrition

Examining the association between muscle mass, muscle function, and fat indexes in an elderly population

(2020) Yuan-Ping Chao et al.   NUTRITION

Sedentary behaviour, physical activity, and sarcopenia among older adults in the TSHA: isotemporal substitution model

(2019) Juan Luis Sánchez‐Sánchez et al.   Journal of Cachexia Sarcopenia and Muscle

Prognostic value of sarcopenic obesity estimated by computed tomography in patients with cardiovascular disease and undergoing surgery

(2019) Masashi Yamashita et al.   Journal of Cardiology

Sarcopenia and its association with falls and fractures in older adults: A systematic review and meta‐analysis

(2019) Suey S.Y. Yeung et al.   Journal of Cachexia Sarcopenia and Muscle

Mechanical loading stimulates hypertrophy in tissue‐engineered skeletal muscle: Molecular and phenotypic responses

(2019) Kathryn W. Aguilar‐Agon et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Sarcopenia

(2019) Alfonso J Cruz-Jentoft et al.   LANCET

Association of sarcopenic obesity with the risk of all-cause mortality among adults over a broad range of different settings: a updated meta-analysis

(2019) Xiaoming Zhang et al.   BMC Geriatrics

Balancing Weight Loss and Sarcopenia in Elderly Patients With Peripheral Artery Disease

(2019) Damianos G. Kokkinidis et al.   Journal of the American Heart Association

Associations Between Measures of Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Cohort Study and Mendelian Randomization Analysis Using the UK Biobank

(2019) Ruth E. Farmer et al.   Journal of the American Heart Association

Adipose lipid turnover and long-term changes in body weight

(2019) P. Arner et al.   NATURE MEDICINE

Critical appraisal of definitions and diagnostic criteria for sarcopenic obesity based on a systematic review

(2019) Lorenzo M. Donini et al.   CLINICAL NUTRITION

Sex differences in the prevalence and adverse outcomes of sarcopenia and sarcopenic obesity in community dwelling elderly in East China using the AWGS criteria

(2019) Yanping Du et al.   BMC Endocrine Disorders

Health Related Quality of Life and Fall Risk Associated with Age Related Body Composition Changes; Sarcopenia, Obesity and Sarcopenic Obesity

(2018) Zeynel Abidin Öztürk et al.   INTERNAL MEDICINE JOURNAL

Oxidative stress is increased in sarcopenia and associated with cardiovascular disease risk in sarcopenic obesity

(2018) Francesco Bellanti et al.   MATURITAS

Muscle mass, BMI, and mortality among adults in the United States: A population-based cohort study

(2018) Matthew K. Abramowitz et al.   PLoS One

Predicted lean body mass, fat mass, and all cause and cause specific mortality in men: prospective US cohort study

(2018) Dong Hoon Lee et al.   BMJ-British Medical Journal

Predicted lean body mass, fat mass, and all cause and cause specific mortality in men: prospective US cohort study

(2018) Dong Hoon Lee et al.   BMJ-British Medical Journal

OUP accepted manuscript

(2018)   AGE AND AGEING

Muscle-specific Perilipin2 down-regulation affects lipid metabolism and induces myofiber hypertrophy

(2018) Maria Conte et al.   Journal of Cachexia Sarcopenia and Muscle

Inter-muscular adipose tissue is associated with adipose tissue inflammation and poorer functional performance in central adiposity

(2018) Jun Pei Lim et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Differences in body composition and physical function related to pure sarcopenia and sarcopenic obesity: A study of community-dwelling older adults in Japan

(2017) Takeshi Kera et al.   Geriatrics & Gerontology International

Age-Related Anabolic Resistance of Myofibrillar Protein Synthesis Is Exacerbated in Obese Inactive Individuals

(2017) Benoit Smeuninx et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Skeletal muscle inflammation and insulin resistance in obesity

(2017) Huaizhu Wu et al.   JOURNAL OF CLINICAL INVESTIGATION

Low Lean Mass With and Without Obesity, and Mortality: Results From the 1999–2004 National Health and Nutrition Examination Survey

(2017) John A Batsis et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The most effective factors to offset sarcopenia and obesity in the older Korean: Physical activity, vitamin D, and protein intake

(2017) Chorong Oh et al.   NUTRITION

Obesity paradox in stroke – Myth or reality? A systematic review

(2017) Lisa Oesch et al.   PLoS One

Phenotype of sarcopenic obesity in older individuals with a history of falling

(2016) Ya Ruth Huo et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Associations of Sarcopenic Obesity and Dynapenic Obesity with Bone Mineral Density and Incident Fractures Over 5–10 Years in Community-Dwelling Older Adults

(2016) David Scott et al.   CALCIFIED TISSUE INTERNATIONAL

Running-Induced Systemic Cathepsin B Secretion Is Associated with Memory Function

(2016) Hyo Youl Moon et al.   Cell Metabolism

Sarcopenia, sarcopenic obesity and inflammation: Results from the 1999–2004 National Health and Nutrition Examination Survey

(2016) John A. Batsis et al.   CLINICAL NUTRITION

Relationship between thigh intermuscular adipose tissue accumulation and number of metabolic syndrome risk factors in middle-aged and older Japanese adults

(2016) Eunji Bang et al.   EXPERIMENTAL GERONTOLOGY

Sarcopenic Obesity and Its Temporal Associations With Changes in Bone Mineral Density, Incident Falls, and Fractures in Older Men: The Concord Health and Ageing in Men Project

(2016) David Scott et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Mid-adulthood cardiometabolic risk factor profiles of sarcopenic obesity

(2016) Jiantao Ma et al.   Obesity

The Association between Sarcopenic Obesity and Depressive Symptoms in Older Japanese Adults

(2016) Shinya Ishii et al.   PLoS One

The impact of obesity on skeletal muscle strength and structure through adolescence to old age

(2015) D. J. Tomlinson et al.   BIOGERONTOLOGY

Relationship between sarcopenic obesity-related phenotypes and inflammatory markers in postmenopausal women

(2015) Maurílio Tiradentes Dutra et al.   CLINICAL PHYSIOLOGY AND FUNCTIONAL IMAGING

Sarcopenic obesity and risk of new onset depressive symptoms in older adults: English Longitudinal Study of Ageing

(2015) M Hamer et al.   INTERNATIONAL JOURNAL OF OBESITY

Implication of Sarcopenia and Sarcopenic Obesity on Lung Function in Healthy Elderly: Using Korean National Health and Nutrition Examination Survey

(2015) Ji Hyun Moon et al.   JOURNAL OF KOREAN MEDICAL SCIENCE

Stroke-Related Sarcopenia: Specific Characteristics

(2015) Nadja Scherbakov et al.   Journal of the American Medical Directors Association

Intramyocellular Lipid and Impaired Myofiber Contraction in Normal Weight and Obese Older Adults

(2015) Seung J. Choi et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Abdominal Obesity and Low Skeletal Muscle Mass Jointly Predict Total Mortality and Cardiovascular Mortality in an Elderly Asian Population

(2015) Shao-Yuan Chuang et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Muscle Quality and Muscle Fat Infiltration in Relation to Incident Mobility Disability and Gait Speed Decline: the Age, Gene/Environment Susceptibility-Reykjavik Study

(2015) Ilse Reinders et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Skeletal muscle myotubes in severe obesity exhibit altered ubiquitin-proteasome and autophagic/lysosomal proteolytic flux

(2015) Lance M. Bollinger et al.   Obesity

The impacts of sarcopenia and obesity on physical performance in the elderly

(2015) Ching-I Chang et al.   Obesity Research & Clinical Practice

Association of Sarcopenic Obesity with Higher Serum High-Sensitivity C-Reactive Protein Levels in Chinese Older Males - A Community-Based Study (Taichung Community Health Study-Elderly, TCHS-E)

(2015) Chuan-Wei Yang et al.   PLoS One

Body mass index and risk of knee osteoarthritis: systematic review and meta-analysis of prospective studies

(2015) Huaqing Zheng et al.   BMJ Open

Sarcopenia and sarcopenic obesity classifications and cardiometabolic risks in older women

(2014) Enivaldo Pereira dos Santos et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Adiponectin: a manifold therapeutic target for metabolic syndrome, diabetes, and coronary disease?

(2014) Enrique Z Fisman et al.   Cardiovascular Diabetology

Sarcopenic Obesity and Risk of Cardiovascular Disease and Mortality: A Population-Based Cohort Study of Older Men

(2014) Janice L. Atkins et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Sarcopenia in Asia: Consensus Report of the Asian Working Group for Sarcopenia

(2014) Liang-Kung Chen et al.   Journal of the American Medical Directors Association

Sarcopenia: An Independent Predictor of Mortality in Community-Dwelling Older Korean Men

(2014) Jung Hee Kim et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

The FNIH Sarcopenia Project: Rationale, Study Description, Conference Recommendations, and Final Estimates

(2014) Stephanie A. Studenski et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Sarcopenia as a Determinant of Blood Pressure in Older Koreans: Findings from the Korea National Health and Nutrition Examination Surveys (KNHANES) 2008–2010

(2014) Kyungdo Han et al.   PLoS One

Sarcopenia and sarcopenic obesity and their association with dyslipidemia in Korean elderly men: the 2008–2010 Korea National Health and Nutrition Examination Survey

(2014) S. J. Baek et al.   JOURNAL OF ENDOCRINOLOGICAL INVESTIGATION

Association of physical activity with sarcopenia and sarcopenic obesity in community-dwelling older adults: the Fourth Korea National Health and Nutrition Examination Survey

(2013) M. Ryu et al.   AGE AND AGEING

Myosteatosis and myofibrosis: Relationship with aging, inflammation and insulin resistance

(2013) Elena Zoico et al.   ARCHIVES OF GERONTOLOGY AND GERIATRICS

Circulating levels of adipokines and IGF-1 are associated with skeletal muscle strength of young and old healthy subjects

(2013) Laura Bucci et al.   BIOGERONTOLOGY

Obesity Paradox Does Exist

(2013) V. Hainer et al.   DIABETES CARE

Increased Plin2 Expression in Human Skeletal Muscle Is Associated with Sarcopenia and Muscle Weakness

(2013) Maria Conte et al.   PLoS One

Sarcopenic obesity

(2013) Matthew F. Bouchonville et al.   Current Opinion in Endocrinology Diabetes and Obesity

Sarcopenic obesity is more closely associated with knee osteoarthritis than is nonsarcopenic obesity: A cross-sectional study

(2012) Sunggun Lee et al.   ARTHRITIS AND RHEUMATISM

Sarcopenia in the aging high-fat fed rat: a pilot study for modeling sarcopenic obesity in rodents

(2012) L. Cornelius Bollheimer et al.   BIOGERONTOLOGY

Thigh muscle attenuation measured by computed tomography was associated with the risk of low bone density in community-dwelling elderly population

(2012) Jung Hee Kim et al.   CLINICAL ENDOCRINOLOGY

Prevalence, Pathophysiology, Health Consequences and Treatment Options of Obesity in the Elderly: A Guideline

(2012) Elisabeth M.H. Mathus-Vliegen et al.   Obesity Facts

Sarcopenic obesity is closely associated with metabolic syndrome

(2012) Chia-Wen Lu et al.   Obesity Research & Clinical Practice

Identification of sarcopenic obesity in postmenopausal women: a cutoff proposal

(2011) R.J. Oliveira et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Age-related differences in lower extremity tissue compartments and associations with physical function in older adults

(2011) Thomas W. Buford et al.   EXPERIMENTAL GERONTOLOGY

Does the Amount of Fat Mass Predict Age-Related Loss of Lean Mass, Muscle Strength, and Muscle Quality in Older Adults?

(2011) A. Koster et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Muscle Quality As a Potential Explanation of the Metabolically Healthy but Obese and Sarcopenic Obese Paradoxes

(2011) Sébastien Barbat-Artigas et al.   Metabolic Syndrome and Related Disorders

Leptin in Sarcopenic Visceral Obesity: Possible Link between Adipocytes and Myocytes

(2011) Katsuhiko Kohara et al.   PLoS One

Asian women have greater abdominal and visceral adiposity than Caucasian women with similar body mass index

(2011) U Lim et al.   Nutrition & Diabetes

Sarcopenia: European consensus on definition and diagnosis: Report of the European Working Group on Sarcopenia in Older People

(2010) A. J. Cruz-Jentoft et al.   AGE AND AGEING

Sarcopenic Obesity: Prevalence and Association With Metabolic Syndrome in the Korean Longitudinal Study on Health and Aging (KLoSHA)

(2010) S. Lim et al.   DIABETES CARE

Longitudinal study of muscle strength, quality, and adipose tissue infiltration

(2009) et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Prevalence of sarcopenia and sarcopenic obesity in Korean adults: the Korean sarcopenic obesity study

(2009) T N Kim et al.   INTERNATIONAL JOURNAL OF OBESITY

Computed tomographic measurements of thigh muscle cross-sectional area and attenuation coefficient predict hip fracture: The health, aging, and body composition study

(2009) Thomas Lang et al.   JOURNAL OF BONE AND MINERAL RESEARCH

Do Muscle Mass, Muscle Density, Strength, and Physical Function Similarly Influence Risk of Hospitalization in Older Adults?

(2009) Peggy Mannen Cawthon et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Skeletal Muscle and Mortality Results From the InCHIANTI Study

(2009) M. Cesari et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Racial differences in body fat distribution among reproductive-aged women

(2009) Mahbubur Rahman et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Sarcopenic/Obesity and Physical Capacity in Older Men and Women: Data From the Nutrition as a Determinant of Successful Aging (NuAge)—the Quebec Longitudinal Study

(2009) Danielle R. Bouchard et al.   Obesity

Preferred Reporting Items for Systematic Reviews and Meta-Analyses: The PRISMA Statement

(2009) David Moher et al.   PLOS MEDICINE