Skeletal muscle myotubes in severe obesity exhibit altered ubiquitin-proteasome and autophagic/lysosomal proteolytic flux

Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

(2016) J. Julie Wu et al.   Aging-US

Proteasome inhibition in skeletal muscle cells unmasks metabolic derangements in type 2 diabetes

(2014) Lubna Al-Khalili et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Autoubiquitination of the 26S Proteasome on Rpn13 Regulates Breakdown of Ubiquitin Conjugates

(2014) H. C. Besche et al.   EMBO JOURNAL

Apoptosis in differentiating C2C12 muscle cells selectively targets Bcl-2-deficient myotubes

(2013) Christian Schöneich et al.   APOPTOSIS

Are cultured human myotubes far from home?

(2013) Vigdis Aas et al.   CELL AND TISSUE RESEARCH

Mechanisms of muscle growth and atrophy in mammals andDrosophila

(2013) Rosanna Piccirillo et al.   DEVELOPMENTAL DYNAMICS

Deubiquitinases in skeletal muscle atrophy

(2013) Simon S. Wing   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Protein breakdown in muscle wasting: Role of autophagy-lysosome and ubiquitin-proteasome

(2013) Marco Sandri   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Association of All-Cause Mortality With Overweight and Obesity Using Standard Body Mass Index Categories

(2013) Katherine M. Flegal et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Severe Obesity

(2012) Joseph A. Houmard et al.   EXERCISE AND SPORT SCIENCES REVIEWS

Mitochondrial lipid oxidation is impaired in cultured myotubes from obese humans

(2011) K E Boyle et al.   INTERNATIONAL JOURNAL OF OBESITY

Lipid-induced insulin resistance is prevented in lean and obese myotubes by AICAR treatment

(2010) Benjamin T. Bikman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Peroxisome Proliferator-Activated Receptor-  Coactivator-1  Overexpression Increases Lipid Oxidation in Myocytes From Extremely Obese Individuals

(2010) L. A. Consitt et al.   DIABETES

Peroxisome Proliferator-activated Receptor γ Coactivator 1α or 1β Overexpression Inhibits Muscle Protein Degradation, Induction of Ubiquitin Ligases, and Disuse Atrophy

(2010) Jeffrey J. Brault et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Protein Metabolism in Human Obesity: A Shift in Focus From Whole-Body to Skeletal Muscle

(2010) Christos S. Katsanos et al.   Obesity

Sarcopenia Exacerbates Obesity-Associated Insulin Resistance and Dysglycemia: Findings from the National Health and Nutrition Examination Survey III

(2010) Preethi Srikanthan et al.   PLoS One

Myostatin reduces Akt/TORC1/p70S6K signaling, inhibiting myoblast differentiation and myotube size

(2009) Anne Ulrike Trendelenburg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Smad2 and 3 transcription factors control muscle mass in adulthood

(2009) Roberta Sartori et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

A Branched-Chain Amino Acid-Related Metabolic Signature that Differentiates Obese and Lean Humans and Contributes to Insulin Resistance

(2009) Christopher B. Newgard et al.   Cell Metabolism

Sarcopenia in an Overweight or Obese Patient Is an Adverse Prognostic Factor in Pancreatic Cancer

(2009) B. H.L. Tan et al.   CLINICAL CANCER RESEARCH

During muscle atrophy, thick, but not thin, filament components are degraded by MuRF1-dependent ubiquitylation

(2009) Shenhav Cohen et al.   JOURNAL OF CELL BIOLOGY

Sarcopenic-obesity and cardiovascular disease risk in the elderly

(2009) W. C. Stephen et al.   Journal of Nutrition Health & Aging

Protocol for high-resolution separation of rodent myosin heavy chain isoforms in a mini-gel electrophoresis system

(2008) Wataru Mizunoya et al.   ANALYTICAL BIOCHEMISTRY

Increased Secretion and Expression of Myostatin in Skeletal Muscle From Extremely Obese Women

(2008) D. S. Hittel et al.   DIABETES

Prevalence and clinical implications of sarcopenic obesity in patients with solid tumours of the respiratory and gastrointestinal tracts: a population-based study

(2008) Carla MM Prado et al.   LANCET ONCOLOGY

Ordered Organelle Degradation during Starvation-induced Autophagy

(2008) Anders Riis Kristensen et al.   MOLECULAR & CELLULAR PROTEOMICS