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Title
Therapy with oncolytic viruses: progress and challenges
Authors
Keywords
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Journal
Nature Reviews Clinical Oncology
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2023-01-11
DOI
10.1038/s41571-022-00719-w
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- (2022) Patrick M. Forde et al. NEW ENGLAND JOURNAL OF MEDICINE
- Neoadjuvant Intravenous Oncolytic Vaccinia Virus Therapy Promotes Anticancer Immunity in Patients
- (2022) Adel Samson et al. Cancer Immunology Research
- Single agent Talimogene Laherparepvec for stage IIIB-IVM1c melanoma patients: A systematic review and meta-analysis
- (2022) Emma H.A. Stahlie et al. CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY
- CORE1: Phase 2, single-arm study of CG0070 combined with pembrolizumab in patients with nonmuscle-invasive bladder cancer (NMIBC) unresponsive to bacillus Calmette-Guerin (BCG).
- (2022) Roger Li et al. JOURNAL OF CLINICAL ONCOLOGY
- Intratumoral oncolytic herpes virus G47∆ for residual or recurrent glioblastoma: a phase 2 trial
- (2022) Tomoki Todo et al. NATURE MEDICINE
- PD-1 Blockade in Mismatch Repair–Deficient, Locally Advanced Rectal Cancer
- (2022) Andrea Cercek et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oncolytic DNX-2401 Virus for Pediatric Diffuse Intrinsic Pontine Glioma
- (2022) Jaime Gállego Pérez-Larraya et al. NEW ENGLAND JOURNAL OF MEDICINE
- Randomized, Double-Blind, Placebo-Controlled, Global Phase III Trial of Talimogene Laherparepvec Combined With Pembrolizumab for Advanced Melanoma
- (2022) Jason A. Chesney et al. JOURNAL OF CLINICAL ONCOLOGY
- Neoadjuvant Cemiplimab for Stage II to IV Cutaneous Squamous-Cell Carcinoma
- (2022) Neil D. Gross et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oncolytic virotherapy-mediated anti-tumor response: a single-cell perspective
- (2021) Egle Ramelyte et al. CANCER CELL
- Interleukin-7-loaded oncolytic adenovirus improves CAR-T cell therapy for glioblastoma
- (2021) Jianhan Huang et al. CANCER IMMUNOLOGY IMMUNOTHERAPY
- Mutations in the IFNγ-JAK-STAT pathway causing resistance to immune checkpoint inhibitors in melanoma increase sensitivity to oncolytic virus treatment.
- (2021) Tan-Trieu Nguyen et al. CLINICAL CANCER RESEARCH
- Cell death as part of Innate Immunity: cause or consequence?
- (2021) Mario Riera‐Romo IMMUNOLOGY
- Can Biomarkers Guide Oncolytic Virus Immunotherapy?
- (2021) Howard L. Kaufman CLINICAL CANCER RESEARCH
- Oncolytic HSV-1 G207 Immunovirotherapy for Pediatric High-Grade Gliomas
- (2021) Gregory K. Friedman et al. NEW ENGLAND JOURNAL OF MEDICINE
- Phase I trial of intratumoral PVSRIPO in patients with unresectable, treatment-refractory melanoma
- (2021) Georgia M Beasley et al. Journal for ImmunoTherapy of Cancer
- Phase I dose-escalation study of endoscopic intratumoral injection of OBP-301 (Telomelysin) with radiotherapy in oesophageal cancer patients unfit for standard treatments
- (2021) Yasuhiro Shirakawa et al. EUROPEAN JOURNAL OF CANCER
- Real-World Experience of Talimogene Laherparepvec (T-VEC) in Old and Oldest-Old Patients with Melanoma: A Retrospective Single Center Study
- (2021) Johannes Kleemann et al. Cancer Management and Research
- Talimogene Laherparepvec (T-VEC) for the Treatment of Advanced Locoregional Melanoma After Failure of Immunotherapy: An International Multi-Institutional Experience
- (2021) Michael J. Carr et al. ANNALS OF SURGICAL ONCOLOGY
- Neoadjuvant talimogene laherparepvec plus surgery versus surgery alone for resectable stage IIIB–IVM1a melanoma: a randomized, open-label, phase 2 trial
- (2021) R. Dummer et al. NATURE MEDICINE
- Combined immunotherapy with controlled interleukin-12 gene therapy and immune checkpoint blockade in recurrent glioblastoma: An open-label, multi-institutional phase I trial
- (2021) E Antonio Chiocca et al. NEURO-ONCOLOGY
- Targeting matrix metalloproteinase MMP3 greatly enhances oncolytic virus mediated tumor therapy
- (2021) Minglong Liang et al. Translational Oncology
- Oncolytic adenovirus targeting TGF-β enhances anti-tumor responses of mesothelin-targeted chimeric antigen receptor T cell therapy against breast cancer
- (2020) Yuxiang Li et al. CELLULAR IMMUNOLOGY
- Real-world use of talimogene laherparepvec in Germany: a retrospective observational study using a prescription database
- (2020) Karly S Louie et al. Future Oncology
- Neoadjuvant checkpoint blockade for cancer immunotherapy
- (2020) Suzanne L. Topalian et al. SCIENCE
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- (2020) Mark R. Middleton et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2020) Myriam Chalabi et al. NATURE MEDICINE
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- (2020) Ruwan Parakrama et al. BMC CANCER
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- (2020) Mathilde Feist et al. CANCER GENE THERAPY
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- (2020) Gregory V. Goldmacher et al. JOURNAL OF CLINICAL ONCOLOGY
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- (2020) Eva Crespo-Rodriguez et al. Journal for ImmunoTherapy of Cancer
- Clinical landscape of oncolytic virus research in 2020
- (2020) Nicholas Macedo et al. Journal for ImmunoTherapy of Cancer
- A Retrospective Chart Review Study of Real-World Use of Talimogene Laherparepvec in Unresectable Stage IIIB–IVM1a Melanoma in Four European Countries
- (2020) Alexander C. J. van Akkooi et al. ADVANCES IN THERAPY
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- The advent of oncolytic virotherapy in oncology: The Rigvir® story
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- Arming an Oncolytic Herpes Simplex Virus Type 1 with a Single-chain Fragment Variable Antibody against PD-1 for Experimental Glioblastoma Therapy
- (2018) Carmela Passaro et al. CLINICAL CANCER RESEARCH
- MEK inhibition enhances oncolytic virus immunotherapy through increased tumor cell killing and T cell activation
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- (2016) Robert H. I. Andtbacka et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
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- (2014) D. W. Sborov et al. CLINICAL CANCER RESEARCH
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- (2014) James M Markert et al. MOLECULAR THERAPY
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- From Scourge to Cure: Tumour-Selective Viral Pathogenesis as a New Strategy against Cancer
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- (2013) J N Kyula et al. ONCOGENE
- Macrophage Delivery of an Oncolytic Virus Abolishes Tumor Regrowth and Metastasis after Chemotherapy or Irradiation
- (2012) M. Muthana et al. CANCER RESEARCH
- Using clinically approved cyclophosphamide regimens to control the humoral immune response to oncolytic viruses
- (2012) K-W Peng et al. GENE THERAPY
- REO-001: A phase I trial of percutaneous intralesional administration of reovirus type 3 dearing (Reolysin®) in patients with advanced solid tumors
- (2012) Don G. Morris et al. INVESTIGATIONAL NEW DRUGS
- A First in Human Phase 1 Study of CG0070, a GM-CSF Expressing Oncolytic Adenovirus, for the Treatment of Nonmuscle Invasive Bladder Cancer
- (2012) James M. Burke et al. JOURNAL OF UROLOGY
- Reovirus: A Targeted Therapeutic--Progress And Potential
- (2012) R. Maitra et al. MOLECULAR CANCER RESEARCH
- Oncolytic virotherapy
- (2012) Stephen J Russell et al. NATURE BIOTECHNOLOGY
- Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma
- (2012) Michael A. Postow et al. NEW ENGLAND JOURNAL OF MEDICINE
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- Phase I/II Study of Oncolytic HSVGM-CSF in Combination with Radiotherapy and Cisplatin in Untreated Stage III/IV Squamous Cell Cancer of the Head and Neck
- (2010) K. J. Harrington et al. CLINICAL CANCER RESEARCH
- Clinical trials with oncolytic reovirus: Moving beyond phase I into combinations with standard therapeutics
- (2010) K.J. Harrington et al. CYTOKINE & GROWTH FACTOR REVIEWS
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Mesenchymal Stem Cell Carriers Protect Oncolytic Measles Viruses from Antibody Neutralization in an Orthotopic Ovarian Cancer Therapy Model
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- Phase II Clinical Trial of a Granulocyte-Macrophage Colony-Stimulating Factor–Encoding, Second-Generation Oncolytic Herpesvirus in Patients With Unresectable Metastatic Melanoma
- (2009) Neil N. Senzer et al. JOURNAL OF CLINICAL ONCOLOGY
- Recombinant Human Granulocyte-macrophage Colony-stimulating Factor (GM-CSF, Sargramostim) Administered for 3 Years as Adjuvant Therapy of Stages II(T4), III, and IV Melanoma
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- (2008) D. Dhar et al. JOURNAL OF VIROLOGY
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